Continental-Scale Footprint of Balancing and Positive Selection in a Small Rodent (Microtus arvalis) ...
Genetic adaptation to different environmental conditions is expected to lead to large differences between populations at selected loci, thus providing a signature of positive selection. Whereas balancing selection can maintain polymorphisms over long evolutionary periods and even geographic scale, t...
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Online Access: | https://dx.doi.org/10.3929/ethz-b-000091526 http://hdl.handle.net/20.500.11850/91526 |
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ftdatacite:10.3929/ethz-b-000091526 2024-04-28T08:16:13+00:00 Continental-Scale Footprint of Balancing and Positive Selection in a Small Rodent (Microtus arvalis) ... Fischer, Martin C. Foll, Matthieu Heckel, Gerald Excoffier, Laurent 2014 application/pdf https://dx.doi.org/10.3929/ethz-b-000091526 http://hdl.handle.net/20.500.11850/91526 en eng ETH Zurich info:eu-repo/semantics/openAccess Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 article-journal Text ScholarlyArticle Journal Article 2014 ftdatacite https://doi.org/10.3929/ethz-b-000091526 2024-04-02T12:33:25Z Genetic adaptation to different environmental conditions is expected to lead to large differences between populations at selected loci, thus providing a signature of positive selection. Whereas balancing selection can maintain polymorphisms over long evolutionary periods and even geographic scale, thus leads to low levels of divergence between populations at selected loci. However, little is known about the relative importance of these two selective forces in shaping genomic diversity, partly due to difficulties in recognizing balancing selection in species showing low levels of differentiation. Here we address this problem by studying genomic diversity in the European common vole (Microtus arvalis) presenting high levels of differentiation between populations (average FST = 0.31). We studied 3,839 Amplified Fragment Length Polymorphism (AFLP) markers genotyped in 444 individuals from 21 populations distributed across the European continent and hence over different environmental conditions. Our statistical ... : PLoS ONE, 9 (11) ... Article in Journal/Newspaper Common vole Microtus arvalis DataCite Metadata Store (German National Library of Science and Technology) |
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Open Polar |
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DataCite Metadata Store (German National Library of Science and Technology) |
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ftdatacite |
language |
English |
description |
Genetic adaptation to different environmental conditions is expected to lead to large differences between populations at selected loci, thus providing a signature of positive selection. Whereas balancing selection can maintain polymorphisms over long evolutionary periods and even geographic scale, thus leads to low levels of divergence between populations at selected loci. However, little is known about the relative importance of these two selective forces in shaping genomic diversity, partly due to difficulties in recognizing balancing selection in species showing low levels of differentiation. Here we address this problem by studying genomic diversity in the European common vole (Microtus arvalis) presenting high levels of differentiation between populations (average FST = 0.31). We studied 3,839 Amplified Fragment Length Polymorphism (AFLP) markers genotyped in 444 individuals from 21 populations distributed across the European continent and hence over different environmental conditions. Our statistical ... : PLoS ONE, 9 (11) ... |
format |
Article in Journal/Newspaper |
author |
Fischer, Martin C. Foll, Matthieu Heckel, Gerald Excoffier, Laurent |
spellingShingle |
Fischer, Martin C. Foll, Matthieu Heckel, Gerald Excoffier, Laurent Continental-Scale Footprint of Balancing and Positive Selection in a Small Rodent (Microtus arvalis) ... |
author_facet |
Fischer, Martin C. Foll, Matthieu Heckel, Gerald Excoffier, Laurent |
author_sort |
Fischer, Martin C. |
title |
Continental-Scale Footprint of Balancing and Positive Selection in a Small Rodent (Microtus arvalis) ... |
title_short |
Continental-Scale Footprint of Balancing and Positive Selection in a Small Rodent (Microtus arvalis) ... |
title_full |
Continental-Scale Footprint of Balancing and Positive Selection in a Small Rodent (Microtus arvalis) ... |
title_fullStr |
Continental-Scale Footprint of Balancing and Positive Selection in a Small Rodent (Microtus arvalis) ... |
title_full_unstemmed |
Continental-Scale Footprint of Balancing and Positive Selection in a Small Rodent (Microtus arvalis) ... |
title_sort |
continental-scale footprint of balancing and positive selection in a small rodent (microtus arvalis) ... |
publisher |
ETH Zurich |
publishDate |
2014 |
url |
https://dx.doi.org/10.3929/ethz-b-000091526 http://hdl.handle.net/20.500.11850/91526 |
genre |
Common vole Microtus arvalis |
genre_facet |
Common vole Microtus arvalis |
op_rights |
info:eu-repo/semantics/openAccess Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 |
op_doi |
https://doi.org/10.3929/ethz-b-000091526 |
_version_ |
1797581394364334080 |