Demographic History, Adaptation, and NRAP Convergent Evolution at Amino Acid Residue 100 in the World Northernmost Cattle from Siberia ...

• Main Authors: Buggiotti, L, Yurchenko, AA, Yudin, NS, Jagt, CJ Vander, Vorobieva, NV, Kusliy, MA, Vasiliev, SK, Rodionov, AN, Boronetskaya, OI, Zinovieva, NA, Graphodatsky, AS, Daetwyler, Hans, Larkin, DM
• Format: Text
• Language: unknown
• Published: La Trobe 2021
• Subjects: Uncategorized; Kholmogory; Yakut; Siberia
• Online Access: https://dx.doi.org/10.26181/6136bfc30a595; https://opal.latrobe.edu.au/articles/journal_contribution/Demographic_History_Adaptation_and_NRAP_Convergent_Evolution_at_Amino_Acid_Residue_100_in_the_World_Northernmost_Cattle_from_Siberia/16575221

Native cattle breeds represent an important cultural heritage. They are a reservoir of genetic variation useful for properly responding to agriculture needs in the light of ongoing climate changes. Evolutionary processes that occur in response to extreme environmental conditions could also be better understood using adapted local populations. Herein, different evolutionary histories of the world northernmost native cattle breeds from Russia were investigated. They highlighted Kholmogory as a typical taurine cattle, whereas Yakut cattle separated from European taurines approximately 5,000 years ago and contain numerous ancestral and some novel genetic variants allowing their adaptation to harsh conditions of living above the Polar Circle. Scans for selection signatures pointed to several common gene pathways related to adaptation to harsh climates in both breeds. But genes affected by selection from these pathways were mostly different. A Yakut cattle breed-specific missense mutation in a highly conserved ...