Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ...
The Qinghai-Tibet Plateau (QTP), possesses a climate as cold as that of the Arctic, and also presents uniquely low oxygen concentrations and intense ultraviolet (UV) radiation. QTP animals have adapted to these extreme conditions, but whether they obtained genetic variations from the Arctic during c...
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La Trobe
2022
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ftdatacite:10.26181/21569649.v1 2024-04-28T08:06:08+00:00 Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ... Hu, L Long, J Lin, Y Gu, Z Su, H Dong, X Lin, Z Xiao, Q Batbayar, N Bold, B Deutschová, L Ganusevich, S Sokolov, V Sokolov, A Patel, HR Waters, PD Graves, Jennifer Dixon, A Pan, S Zhan, X 2022 https://dx.doi.org/10.26181/21569649.v1 https://opal.latrobe.edu.au/articles/journal_contribution/Arctic_introgression_and_chromatin_regulation_facilitated_rapid_Qinghai-Tibet_Plateau_colonization_by_an_avian_predator/21569649/1 unknown La Trobe https://dx.doi.org/10.26181/21569649 https://dx.doi.org/10.1038/s41467-022-34138-3 Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 Ecology not elsewhere classified Genetics not elsewhere classified Journal contribution article-journal Text ScholarlyArticle 2022 ftdatacite https://doi.org/10.26181/21569649.v110.26181/2156964910.1038/s41467-022-34138-3 2024-04-02T09:29:06Z The Qinghai-Tibet Plateau (QTP), possesses a climate as cold as that of the Arctic, and also presents uniquely low oxygen concentrations and intense ultraviolet (UV) radiation. QTP animals have adapted to these extreme conditions, but whether they obtained genetic variations from the Arctic during cold adaptation, and how genomic mutations in non-coding regions regulate gene expression under hypoxia and intense UV environment, remain largely unknown. Here, we assemble a high-quality saker falcon genome and resequence populations across Eurasia. We identify female-biased hybridization with Arctic gyrfalcons in the last glacial maximum, that endowed eastern sakers with alleles conveying larger body size and changes in fat metabolism, predisposing their QTP cold adaptation. We discover that QTP hypoxia and UV adaptations mainly involve independent changes in non-coding genomic variants. Our study highlights key roles of gene flow from Arctic relatives during QTP hypothermia adaptation, and cis-regulatory ... Text Arctic DataCite Metadata Store (German National Library of Science and Technology) |
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Open Polar |
collection |
DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
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language |
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topic |
Ecology not elsewhere classified Genetics not elsewhere classified |
spellingShingle |
Ecology not elsewhere classified Genetics not elsewhere classified Hu, L Long, J Lin, Y Gu, Z Su, H Dong, X Lin, Z Xiao, Q Batbayar, N Bold, B Deutschová, L Ganusevich, S Sokolov, V Sokolov, A Patel, HR Waters, PD Graves, Jennifer Dixon, A Pan, S Zhan, X Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ... |
topic_facet |
Ecology not elsewhere classified Genetics not elsewhere classified |
description |
The Qinghai-Tibet Plateau (QTP), possesses a climate as cold as that of the Arctic, and also presents uniquely low oxygen concentrations and intense ultraviolet (UV) radiation. QTP animals have adapted to these extreme conditions, but whether they obtained genetic variations from the Arctic during cold adaptation, and how genomic mutations in non-coding regions regulate gene expression under hypoxia and intense UV environment, remain largely unknown. Here, we assemble a high-quality saker falcon genome and resequence populations across Eurasia. We identify female-biased hybridization with Arctic gyrfalcons in the last glacial maximum, that endowed eastern sakers with alleles conveying larger body size and changes in fat metabolism, predisposing their QTP cold adaptation. We discover that QTP hypoxia and UV adaptations mainly involve independent changes in non-coding genomic variants. Our study highlights key roles of gene flow from Arctic relatives during QTP hypothermia adaptation, and cis-regulatory ... |
format |
Text |
author |
Hu, L Long, J Lin, Y Gu, Z Su, H Dong, X Lin, Z Xiao, Q Batbayar, N Bold, B Deutschová, L Ganusevich, S Sokolov, V Sokolov, A Patel, HR Waters, PD Graves, Jennifer Dixon, A Pan, S Zhan, X |
author_facet |
Hu, L Long, J Lin, Y Gu, Z Su, H Dong, X Lin, Z Xiao, Q Batbayar, N Bold, B Deutschová, L Ganusevich, S Sokolov, V Sokolov, A Patel, HR Waters, PD Graves, Jennifer Dixon, A Pan, S Zhan, X |
author_sort |
Hu, L |
title |
Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ... |
title_short |
Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ... |
title_full |
Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ... |
title_fullStr |
Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ... |
title_full_unstemmed |
Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ... |
title_sort |
arctic introgression and chromatin regulation facilitated rapid qinghai-tibet plateau colonization by an avian predator ... |
publisher |
La Trobe |
publishDate |
2022 |
url |
https://dx.doi.org/10.26181/21569649.v1 https://opal.latrobe.edu.au/articles/journal_contribution/Arctic_introgression_and_chromatin_regulation_facilitated_rapid_Qinghai-Tibet_Plateau_colonization_by_an_avian_predator/21569649/1 |
genre |
Arctic |
genre_facet |
Arctic |
op_relation |
https://dx.doi.org/10.26181/21569649 https://dx.doi.org/10.1038/s41467-022-34138-3 |
op_rights |
Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 |
op_doi |
https://doi.org/10.26181/21569649.v110.26181/2156964910.1038/s41467-022-34138-3 |
_version_ |
1797575788543868928 |