Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ...

The Qinghai-Tibet Plateau (QTP), possesses a climate as cold as that of the Arctic, and also presents uniquely low oxygen concentrations and intense ultraviolet (UV) radiation. QTP animals have adapted to these extreme conditions, but whether they obtained genetic variations from the Arctic during c...

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Main Authors: Hu, L, Long, J, Lin, Y, Gu, Z, Su, H, Dong, X, Lin, Z, Xiao, Q, Batbayar, N, Bold, B, Deutschová, L, Ganusevich, S, Sokolov, V, Sokolov, A, Patel, HR, Waters, PD, Graves, Jennifer, Dixon, A, Pan, S, Zhan, X
Format: Text
Language:unknown
Published: La Trobe 2022
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Online Access:https://dx.doi.org/10.26181/21569649.v1
https://opal.latrobe.edu.au/articles/journal_contribution/Arctic_introgression_and_chromatin_regulation_facilitated_rapid_Qinghai-Tibet_Plateau_colonization_by_an_avian_predator/21569649/1
id ftdatacite:10.26181/21569649.v1
record_format openpolar
spelling ftdatacite:10.26181/21569649.v1 2024-04-28T08:06:08+00:00 Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ... Hu, L Long, J Lin, Y Gu, Z Su, H Dong, X Lin, Z Xiao, Q Batbayar, N Bold, B Deutschová, L Ganusevich, S Sokolov, V Sokolov, A Patel, HR Waters, PD Graves, Jennifer Dixon, A Pan, S Zhan, X 2022 https://dx.doi.org/10.26181/21569649.v1 https://opal.latrobe.edu.au/articles/journal_contribution/Arctic_introgression_and_chromatin_regulation_facilitated_rapid_Qinghai-Tibet_Plateau_colonization_by_an_avian_predator/21569649/1 unknown La Trobe https://dx.doi.org/10.26181/21569649 https://dx.doi.org/10.1038/s41467-022-34138-3 Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 Ecology not elsewhere classified Genetics not elsewhere classified Journal contribution article-journal Text ScholarlyArticle 2022 ftdatacite https://doi.org/10.26181/21569649.v110.26181/2156964910.1038/s41467-022-34138-3 2024-04-02T09:29:06Z The Qinghai-Tibet Plateau (QTP), possesses a climate as cold as that of the Arctic, and also presents uniquely low oxygen concentrations and intense ultraviolet (UV) radiation. QTP animals have adapted to these extreme conditions, but whether they obtained genetic variations from the Arctic during cold adaptation, and how genomic mutations in non-coding regions regulate gene expression under hypoxia and intense UV environment, remain largely unknown. Here, we assemble a high-quality saker falcon genome and resequence populations across Eurasia. We identify female-biased hybridization with Arctic gyrfalcons in the last glacial maximum, that endowed eastern sakers with alleles conveying larger body size and changes in fat metabolism, predisposing their QTP cold adaptation. We discover that QTP hypoxia and UV adaptations mainly involve independent changes in non-coding genomic variants. Our study highlights key roles of gene flow from Arctic relatives during QTP hypothermia adaptation, and cis-regulatory ... Text Arctic DataCite Metadata Store (German National Library of Science and Technology)
institution Open Polar
collection DataCite Metadata Store (German National Library of Science and Technology)
op_collection_id ftdatacite
language unknown
topic Ecology not elsewhere classified
Genetics not elsewhere classified
spellingShingle Ecology not elsewhere classified
Genetics not elsewhere classified
Hu, L
Long, J
Lin, Y
Gu, Z
Su, H
Dong, X
Lin, Z
Xiao, Q
Batbayar, N
Bold, B
Deutschová, L
Ganusevich, S
Sokolov, V
Sokolov, A
Patel, HR
Waters, PD
Graves, Jennifer
Dixon, A
Pan, S
Zhan, X
Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ...
topic_facet Ecology not elsewhere classified
Genetics not elsewhere classified
description The Qinghai-Tibet Plateau (QTP), possesses a climate as cold as that of the Arctic, and also presents uniquely low oxygen concentrations and intense ultraviolet (UV) radiation. QTP animals have adapted to these extreme conditions, but whether they obtained genetic variations from the Arctic during cold adaptation, and how genomic mutations in non-coding regions regulate gene expression under hypoxia and intense UV environment, remain largely unknown. Here, we assemble a high-quality saker falcon genome and resequence populations across Eurasia. We identify female-biased hybridization with Arctic gyrfalcons in the last glacial maximum, that endowed eastern sakers with alleles conveying larger body size and changes in fat metabolism, predisposing their QTP cold adaptation. We discover that QTP hypoxia and UV adaptations mainly involve independent changes in non-coding genomic variants. Our study highlights key roles of gene flow from Arctic relatives during QTP hypothermia adaptation, and cis-regulatory ...
format Text
author Hu, L
Long, J
Lin, Y
Gu, Z
Su, H
Dong, X
Lin, Z
Xiao, Q
Batbayar, N
Bold, B
Deutschová, L
Ganusevich, S
Sokolov, V
Sokolov, A
Patel, HR
Waters, PD
Graves, Jennifer
Dixon, A
Pan, S
Zhan, X
author_facet Hu, L
Long, J
Lin, Y
Gu, Z
Su, H
Dong, X
Lin, Z
Xiao, Q
Batbayar, N
Bold, B
Deutschová, L
Ganusevich, S
Sokolov, V
Sokolov, A
Patel, HR
Waters, PD
Graves, Jennifer
Dixon, A
Pan, S
Zhan, X
author_sort Hu, L
title Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ...
title_short Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ...
title_full Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ...
title_fullStr Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ...
title_full_unstemmed Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator ...
title_sort arctic introgression and chromatin regulation facilitated rapid qinghai-tibet plateau colonization by an avian predator ...
publisher La Trobe
publishDate 2022
url https://dx.doi.org/10.26181/21569649.v1
https://opal.latrobe.edu.au/articles/journal_contribution/Arctic_introgression_and_chromatin_regulation_facilitated_rapid_Qinghai-Tibet_Plateau_colonization_by_an_avian_predator/21569649/1
genre Arctic
genre_facet Arctic
op_relation https://dx.doi.org/10.26181/21569649
https://dx.doi.org/10.1038/s41467-022-34138-3
op_rights Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
cc-by-4.0
op_doi https://doi.org/10.26181/21569649.v110.26181/2156964910.1038/s41467-022-34138-3
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