Ancient human genome sequence of an extinct Palaeo-Eskimo

We report the first ancient human genome. Obtained from ~4000 year old hair preserved in the Greenlandic permafrost, the genome represents a male individual from the first known culture to have settled the New World Arctic. Through the application of biochemical and statistical approaches, we ensure...

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Bibliographic Details
Main Author: BGI
Format: Dataset
Language:English
Published: CNGB 2010
Subjects:
Online Access:https://dx.doi.org/10.26036/cnphis0000118
https://db.cngb.org/search/project/CNPhis0000118/
Description
Summary:We report the first ancient human genome. Obtained from ~4000 year old hair preserved in the Greenlandic permafrost, the genome represents a male individual from the first known culture to have settled the New World Arctic. Through the application of biochemical and statistical approaches, we ensured that the effect of DNA-damage and sequencing derived errors is negligible. Sequenced to an average depth of 20x, we recover 79% of the diploid genome, an amount close to the practical limit of current sequencing technologies.