Molecular assessment of resistance to amoebic gill disease ...

• Main Author: Wynne, JW
• Format: Thesis
• Language: unknown
• Published: University Of Tasmania 2023
• Subjects: Atlantic salmon; Salmo salar
• Online Access: https://dx.doi.org/10.25959/23248295; https://figshare.utas.edu.au/articles/thesis/Molecular_assessment_of_resistance_to_amoebic_gill_disease/23248295

Amoebic gill disease (AGD) is the most significant health issue affecting the culture of Atlantic salmon (Salmo salar L.) in Tasmania, Australia. Recent research has suggested that heritable variation in AGD resistance exists within the Tasmanian Atlantic salmon population. Subsequently, enhancing this resistance through selective breeding has become a major research focus in Tasmania. The mechanisms controlling this commercially important trait remain poorly understood. To this end, an investigation of the molecular mechanisms controlling AGD resistance was conducted. Due to their high polymorphism and important immune function genes of the major histocompatibility complex (MHC) - known as the MH genes in Atlantic salmon - represent some of the best candidate loci with a possible influence upon AGD resistance. With this in mind, the amount of MH variation and its association with resistance to AGD was investigated. In contrast to what has been previously reported at non-coding microsatellite loci, a high ...