DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018

A custom DNA methylation array was used to measure methylation levels at 37,488 cytosine-guanine sites (CpGs) in the beluga genome using a calibration dataset of deceased beluga whales with estimated chronological ages (n=69) using tooth growth layers. Data were generated on a bead array using Illum...

Full description

Bibliographic Details
Main Authors: Baker, Charles Scott, Bors, Eleanor, Wade, Paul, Horvath, Steve
Format: Dataset
Language:English
Published: Axiom Data Science 2021
Subjects:
Beluga
Beluga*
Alaska
Online Access:https://dx.doi.org/10.24431/rw1k57n
https://search.dataone.org/#view/10.24431/rw1k57n
id ftdatacite:10.24431/rw1k57n
record_format openpolar
spelling ftdatacite:10.24431/rw1k57n 2023-05-15T15:41:40+02:00 DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018 Baker, Charles Scott Bors, Eleanor Wade, Paul Horvath, Steve 2021 https://dx.doi.org/10.24431/rw1k57n https://search.dataone.org/#view/10.24431/rw1k57n en eng Axiom Data Science dataset Dataset 2021 ftdatacite https://doi.org/10.24431/rw1k57n 2021-11-05T12:55:41Z A custom DNA methylation array was used to measure methylation levels at 37,488 cytosine-guanine sites (CpGs) in the beluga genome using a calibration dataset of deceased beluga whales with estimated chronological ages (n=69) using tooth growth layers. Data were generated on a bead array using Illumina Infinium technology. IDAT files (with measures of fluorescence from the iScan machine) were produced and normalized data were uploaded here. Data were normalized using the SeSAMe pipeline (Zhou et al., 2018). Date files are uploaded for (1) the epigenetic clock calibration dataset and (2) a dataset of whales of unkown age, or the "biopsy dataset." The calibration dataset is for whales that have chronological ages derived from tooth growth layer group counts. The biopsy dataset consists of whales of unknown age that are living in Cook Inlet and were sampled by biopsy dart in 2016-2018. All samples were of skin tissue. Data here includes (1) beta values for each sample for each probe on the array and (2) detection p-values describing the confidence in those beta values. Dataset Beluga Beluga* Alaska DataCite Metadata Store (German National Library of Science and Technology)
institution Open Polar
collection DataCite Metadata Store (German National Library of Science and Technology)
op_collection_id ftdatacite
language English
description A custom DNA methylation array was used to measure methylation levels at 37,488 cytosine-guanine sites (CpGs) in the beluga genome using a calibration dataset of deceased beluga whales with estimated chronological ages (n=69) using tooth growth layers. Data were generated on a bead array using Illumina Infinium technology. IDAT files (with measures of fluorescence from the iScan machine) were produced and normalized data were uploaded here. Data were normalized using the SeSAMe pipeline (Zhou et al., 2018). Date files are uploaded for (1) the epigenetic clock calibration dataset and (2) a dataset of whales of unkown age, or the "biopsy dataset." The calibration dataset is for whales that have chronological ages derived from tooth growth layer group counts. The biopsy dataset consists of whales of unknown age that are living in Cook Inlet and were sampled by biopsy dart in 2016-2018. All samples were of skin tissue. Data here includes (1) beta values for each sample for each probe on the array and (2) detection p-values describing the confidence in those beta values.
format Dataset
author Baker, Charles Scott
Bors, Eleanor
Wade, Paul
Horvath, Steve
spellingShingle Baker, Charles Scott
Bors, Eleanor
Wade, Paul
Horvath, Steve
DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018
author_facet Baker, Charles Scott
Bors, Eleanor
Wade, Paul
Horvath, Steve
author_sort Baker, Charles Scott
title DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018
title_short DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018
title_full DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018
title_fullStr DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018
title_full_unstemmed DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018
title_sort dna methylation beta values at 37,488 cpg sites for beluga whales collected in cook inlet, alaska, between 1992 and 2018
publisher Axiom Data Science
publishDate 2021
url https://dx.doi.org/10.24431/rw1k57n
https://search.dataone.org/#view/10.24431/rw1k57n
genre Beluga
Beluga*
Alaska
genre_facet Beluga
Beluga*
Alaska
op_doi https://doi.org/10.24431/rw1k57n
_version_ 1766374553840254976

Similar Items