DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018
A custom DNA methylation array was used to measure methylation levels at 37,488 cytosine-guanine sites (CpGs) in the beluga genome using a calibration dataset of deceased beluga whales with estimated chronological ages (n=69) using tooth growth layers. Data were generated on a bead array using Illum...
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Axiom Data Science
2021
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Online Access: | https://dx.doi.org/10.24431/rw1k57m https://search.dataone.org/#view/10.24431/rw1k57m |
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ftdatacite:10.24431/rw1k57m 2023-05-15T15:41:40+02:00 DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018 Baker, Charles Scott Bors, Eleanor Wade, Paul Horvath, Steve 2021 https://dx.doi.org/10.24431/rw1k57m https://search.dataone.org/#view/10.24431/rw1k57m en eng Axiom Data Science dataset Dataset 2021 ftdatacite https://doi.org/10.24431/rw1k57m 2021-11-05T12:55:41Z A custom DNA methylation array was used to measure methylation levels at 37,488 cytosine-guanine sites (CpGs) in the beluga genome using a calibration dataset of deceased beluga whales with estimated chronological ages (n=69) using tooth growth layers. Data were generated on a bead array using Illumina Infinium technology. IDAT files (with measures of fluorescence from the iScan machine) were produced and normalized data were uploaded here. Data were normalized using the SeSAMe pipeline (Zhou et al., 2018). Date files are uploaded for (1) the epigenetic clock calibration dataset and (2) a dataset of whales of unkown age, or the "biopsy dataset." The calibration dataset is for whales that have chronological ages derived from tooth growth layer group counts. The biopsy dataset consists of whales of unknown age that are living in Cook Inlet and were sampled by biopsy dart in 2016-2018. All samples were of skin tissue. Data here includes (1) beta values for each sample for each probe on the array and (2) detection p-values describing the confidence in those beta values. Dataset Beluga Beluga* Alaska DataCite Metadata Store (German National Library of Science and Technology) |
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Open Polar |
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DataCite Metadata Store (German National Library of Science and Technology) |
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ftdatacite |
language |
English |
description |
A custom DNA methylation array was used to measure methylation levels at 37,488 cytosine-guanine sites (CpGs) in the beluga genome using a calibration dataset of deceased beluga whales with estimated chronological ages (n=69) using tooth growth layers. Data were generated on a bead array using Illumina Infinium technology. IDAT files (with measures of fluorescence from the iScan machine) were produced and normalized data were uploaded here. Data were normalized using the SeSAMe pipeline (Zhou et al., 2018). Date files are uploaded for (1) the epigenetic clock calibration dataset and (2) a dataset of whales of unkown age, or the "biopsy dataset." The calibration dataset is for whales that have chronological ages derived from tooth growth layer group counts. The biopsy dataset consists of whales of unknown age that are living in Cook Inlet and were sampled by biopsy dart in 2016-2018. All samples were of skin tissue. Data here includes (1) beta values for each sample for each probe on the array and (2) detection p-values describing the confidence in those beta values. |
format |
Dataset |
author |
Baker, Charles Scott Bors, Eleanor Wade, Paul Horvath, Steve |
spellingShingle |
Baker, Charles Scott Bors, Eleanor Wade, Paul Horvath, Steve DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018 |
author_facet |
Baker, Charles Scott Bors, Eleanor Wade, Paul Horvath, Steve |
author_sort |
Baker, Charles Scott |
title |
DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018 |
title_short |
DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018 |
title_full |
DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018 |
title_fullStr |
DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018 |
title_full_unstemmed |
DNA methylation beta values at 37,488 CpG sites for beluga whales collected in Cook Inlet, Alaska, between 1992 and 2018 |
title_sort |
dna methylation beta values at 37,488 cpg sites for beluga whales collected in cook inlet, alaska, between 1992 and 2018 |
publisher |
Axiom Data Science |
publishDate |
2021 |
url |
https://dx.doi.org/10.24431/rw1k57m https://search.dataone.org/#view/10.24431/rw1k57m |
genre |
Beluga Beluga* Alaska |
genre_facet |
Beluga Beluga* Alaska |
op_doi |
https://doi.org/10.24431/rw1k57m |
_version_ |
1766374553644171264 |