Effects of dietary additives on growth performance, immunity and mucosal barrier defences of salmonids ...

• Main Author: Pontefract, Nicola
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: University of Plymouth 2021
• Subjects: Feed additives; Salmonids; Aquacutlure; Mucosal associated lymphoid tissues; Sea lice; qPCR; PhD; Atlantic salmon; Salmo salar
• Online Access: https://dx.doi.org/10.24382/1041; https://pearl-prod.plymouth.ac.uk/handle/10026.1/17114

Chapter 4 publication: E, Leclercq., N, Pontefract., M, Rawling., V, Valdenegro., E, Aasum., L, Vera., H, Migaud., M, Castex., D, Merrifield (2020). Dietary supplementation with a specific mannan-rich yeast parietal fraction enhances the gut and skin mucosal barriers of Atlantic salmon (Salmo salar) and reduces its susceptibility to sea lice (Lepeophtheirus salmonis). Aquaculture 529. DOI: https://doi.org/10.1016/j.aquaculture.2020.735701 ... : The mucosal surfaces of fish are considered highly active immunological sites that work to maintain homeostasis and play a key role in the defence against pathogens (Yu et al., 2020). While disease represents a major constraint to the aquaculture industry, the potential influence of dietary additives upon the mucosal barriers and defences of fish is the subject of increasing amounts of research. RT-q-PCR gene expression analysis and histological examinations of experiment one jointly indicate the potential of a dietary prebiotic mixture, a parabiotic and their synbiotic to positively influence the mucosal barrier defences of the Gill-(GIALT), Skin-(SALT) and Gut- associated lymphoid tissues (GALT) of rainbow trout. Significant increases in goblet cell area fraction (CAF) were observed in the SALT, in addition to significantly elevated expressions of tight junction-, mucosal- and immunity-associated genes, within the GIALT, SALT and GALT. Similar results were observed for Atlantic salmon fed prebiotic- and ...