Concentrations of phthtalates and their potential to transactivate nuclear receptors in marine mammals from the Norwegian Arctic
Phthalate diester concentrations were measured in blubber/adipose tissue of blue whales (Balaenoptera musculus), fin whales (Balaenoptera physalus), bowhead whales (Balaena mysticetus) and polar bears (Ursus maritimus) sampled from the Barents and Greenland seas. Additionally, plasma samples from po...
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2021
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ftdatacite:10.21334/npolar.2021.5499f1ad 2023-05-15T14:59:39+02:00 Concentrations of phthtalates and their potential to transactivate nuclear receptors in marine mammals from the Norwegian Arctic Routti, Heli Harju, Mikael Luhmann, Katharina Aars, Jon Goksøyr, Anders Kovacs, Kit M. Lydersen, Christian 2021 https://dx.doi.org/10.21334/npolar.2021.5499f1ad https://data.npolar.no/dataset/5499f1ad-cbca-4aa5-b986-5891f0c60ad2 unknown npolar.no https://data.npolar.no/dataset/5499f1ad-cbca-4aa5-b986-5891f0c60ad2 Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 CC-BY dataset Dataset 2021 ftdatacite https://doi.org/10.21334/npolar.2021.5499f1ad 2021-11-05T12:55:41Z Phthalate diester concentrations were measured in blubber/adipose tissue of blue whales (Balaenoptera musculus), fin whales (Balaenoptera physalus), bowhead whales (Balaena mysticetus) and polar bears (Ursus maritimus) sampled from the Barents and Greenland seas. Additionally, plasma samples from polar bears were analysed for total concentrations of phthalate monoester metabolites including their free and glucuronated forms. In vitro reporter gene assays were used to assess transcriptional activity of fin whale nuclear receptors by selected phthalates. Membrane integrity and metabolic activity were monitored as a measure for the viability of the cells used for reportor gene assays. Dataset Arctic Balaena mysticetus Balaenoptera musculus Balaenoptera physalus Fin whale Greenland Ursus maritimus DataCite Metadata Store (German National Library of Science and Technology) Arctic Greenland |
institution |
Open Polar |
collection |
DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
ftdatacite |
language |
unknown |
description |
Phthalate diester concentrations were measured in blubber/adipose tissue of blue whales (Balaenoptera musculus), fin whales (Balaenoptera physalus), bowhead whales (Balaena mysticetus) and polar bears (Ursus maritimus) sampled from the Barents and Greenland seas. Additionally, plasma samples from polar bears were analysed for total concentrations of phthalate monoester metabolites including their free and glucuronated forms. In vitro reporter gene assays were used to assess transcriptional activity of fin whale nuclear receptors by selected phthalates. Membrane integrity and metabolic activity were monitored as a measure for the viability of the cells used for reportor gene assays. |
format |
Dataset |
author |
Routti, Heli Harju, Mikael Luhmann, Katharina Aars, Jon Goksøyr, Anders Kovacs, Kit M. Lydersen, Christian |
spellingShingle |
Routti, Heli Harju, Mikael Luhmann, Katharina Aars, Jon Goksøyr, Anders Kovacs, Kit M. Lydersen, Christian Concentrations of phthtalates and their potential to transactivate nuclear receptors in marine mammals from the Norwegian Arctic |
author_facet |
Routti, Heli Harju, Mikael Luhmann, Katharina Aars, Jon Goksøyr, Anders Kovacs, Kit M. Lydersen, Christian |
author_sort |
Routti, Heli |
title |
Concentrations of phthtalates and their potential to transactivate nuclear receptors in marine mammals from the Norwegian Arctic |
title_short |
Concentrations of phthtalates and their potential to transactivate nuclear receptors in marine mammals from the Norwegian Arctic |
title_full |
Concentrations of phthtalates and their potential to transactivate nuclear receptors in marine mammals from the Norwegian Arctic |
title_fullStr |
Concentrations of phthtalates and their potential to transactivate nuclear receptors in marine mammals from the Norwegian Arctic |
title_full_unstemmed |
Concentrations of phthtalates and their potential to transactivate nuclear receptors in marine mammals from the Norwegian Arctic |
title_sort |
concentrations of phthtalates and their potential to transactivate nuclear receptors in marine mammals from the norwegian arctic |
publisher |
npolar.no |
publishDate |
2021 |
url |
https://dx.doi.org/10.21334/npolar.2021.5499f1ad https://data.npolar.no/dataset/5499f1ad-cbca-4aa5-b986-5891f0c60ad2 |
geographic |
Arctic Greenland |
geographic_facet |
Arctic Greenland |
genre |
Arctic Balaena mysticetus Balaenoptera musculus Balaenoptera physalus Fin whale Greenland Ursus maritimus |
genre_facet |
Arctic Balaena mysticetus Balaenoptera musculus Balaenoptera physalus Fin whale Greenland Ursus maritimus |
op_relation |
https://data.npolar.no/dataset/5499f1ad-cbca-4aa5-b986-5891f0c60ad2 |
op_rights |
Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.21334/npolar.2021.5499f1ad |
_version_ |
1766331759957377024 |