Grey wolf genomic history reveals a dual ancestry of dogs. ...
The grey wolf (Canis lupus) was the first species to give rise to a domestic population, and they remained widespread throughout the last Ice Age when many other large mammal species went extinct. Little is known, however, about the history and possible extinction of past wolf populations or when an...
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Online Access: | https://dx.doi.org/10.17863/cam.87108 https://www.repository.cam.ac.uk/handle/1810/339689 |
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ftdatacite:10.17863/cam.87108 2024-02-27T08:39:33+00:00 Grey wolf genomic history reveals a dual ancestry of dogs. ... Bergström, Anders Stanton, David WG Taron, Ulrike H Frantz, Laurent Sinding, Mikkel-Holger S Ersmark, Erik Pfrengle, Saskia Cassatt-Johnstone, Molly Lebrasseur, Ophélie Girdland-Flink, Linus Fernandes, Daniel M Ollivier, Morgane Speidel, Leo Gopalakrishnan, Shyam Westbury, Michael V Ramos-Madrigal, Jazmin Feuerborn, Tatiana R Reiter, Ella Gretzinger, Joscha Münzel, Susanne C Swali, Pooja Conard, Nicholas J Carøe, Christian Haile, James Linderholm, Anna Androsov, Semyon Barnes, Ian Baumann, Chris Benecke, Norbert Bocherens, Hervé Brace, Selina Carden, Ruth F Drucker, Dorothée G Fedorov, Sergey Gasparik, Mihály Germonpré, Mietje Grigoriev, Semyon Groves, Pam Hertwig, Stefan T Ivanova, Varvara V Janssens, Luc Jennings, Richard P Kasparov, Aleksei K Kirillova, Irina V Kurmaniyazov, Islam Kuzmin, Yaroslav V Kosintsev, Pavel A Lázničková-Galetová, Martina Leduc, Charlotte Nikolskiy, Pavel 2022 https://dx.doi.org/10.17863/cam.87108 https://www.repository.cam.ac.uk/handle/1810/339689 en eng Springer Science and Business Media LLC open.access Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 http://purl.org/coar/access_right/c_abf2 Africa Animals DNA, Ancient Dogs Domestication Europe Genome Genomics History, Ancient Middle East Mutation North America Phylogeny Selection, Genetic Siberia Tumor Suppressor Proteins Wolves article-journal ScholarlyArticle JournalArticle Article 2022 ftdatacite https://doi.org/10.17863/cam.87108 2024-02-01T15:02:59Z The grey wolf (Canis lupus) was the first species to give rise to a domestic population, and they remained widespread throughout the last Ice Age when many other large mammal species went extinct. Little is known, however, about the history and possible extinction of past wolf populations or when and where the wolf progenitors of the present-day dog lineage (Canis familiaris) lived1-8. Here we analysed 72 ancient wolf genomes spanning the last 100,000 years from Europe, Siberia and North America. We found that wolf populations were highly connected throughout the Late Pleistocene, with levels of differentiation an order of magnitude lower than they are today. This population connectivity allowed us to detect natural selection across the time series, including rapid fixation of mutations in the gene IFT88 40,000-30,000 years ago. We show that dogs are overall more closely related to ancient wolves from eastern Eurasia than to those from western Eurasia, suggesting a domestication process in the east. However, ... Article in Journal/Newspaper Canis lupus Siberia DataCite Metadata Store (German National Library of Science and Technology) |
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Open Polar |
collection |
DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
ftdatacite |
language |
English |
topic |
Africa Animals DNA, Ancient Dogs Domestication Europe Genome Genomics History, Ancient Middle East Mutation North America Phylogeny Selection, Genetic Siberia Tumor Suppressor Proteins Wolves |
spellingShingle |
Africa Animals DNA, Ancient Dogs Domestication Europe Genome Genomics History, Ancient Middle East Mutation North America Phylogeny Selection, Genetic Siberia Tumor Suppressor Proteins Wolves Bergström, Anders Stanton, David WG Taron, Ulrike H Frantz, Laurent Sinding, Mikkel-Holger S Ersmark, Erik Pfrengle, Saskia Cassatt-Johnstone, Molly Lebrasseur, Ophélie Girdland-Flink, Linus Fernandes, Daniel M Ollivier, Morgane Speidel, Leo Gopalakrishnan, Shyam Westbury, Michael V Ramos-Madrigal, Jazmin Feuerborn, Tatiana R Reiter, Ella Gretzinger, Joscha Münzel, Susanne C Swali, Pooja Conard, Nicholas J Carøe, Christian Haile, James Linderholm, Anna Androsov, Semyon Barnes, Ian Baumann, Chris Benecke, Norbert Bocherens, Hervé Brace, Selina Carden, Ruth F Drucker, Dorothée G Fedorov, Sergey Gasparik, Mihály Germonpré, Mietje Grigoriev, Semyon Groves, Pam Hertwig, Stefan T Ivanova, Varvara V Janssens, Luc Jennings, Richard P Kasparov, Aleksei K Kirillova, Irina V Kurmaniyazov, Islam Kuzmin, Yaroslav V Kosintsev, Pavel A Lázničková-Galetová, Martina Leduc, Charlotte Nikolskiy, Pavel Grey wolf genomic history reveals a dual ancestry of dogs. ... |
topic_facet |
Africa Animals DNA, Ancient Dogs Domestication Europe Genome Genomics History, Ancient Middle East Mutation North America Phylogeny Selection, Genetic Siberia Tumor Suppressor Proteins Wolves |
description |
The grey wolf (Canis lupus) was the first species to give rise to a domestic population, and they remained widespread throughout the last Ice Age when many other large mammal species went extinct. Little is known, however, about the history and possible extinction of past wolf populations or when and where the wolf progenitors of the present-day dog lineage (Canis familiaris) lived1-8. Here we analysed 72 ancient wolf genomes spanning the last 100,000 years from Europe, Siberia and North America. We found that wolf populations were highly connected throughout the Late Pleistocene, with levels of differentiation an order of magnitude lower than they are today. This population connectivity allowed us to detect natural selection across the time series, including rapid fixation of mutations in the gene IFT88 40,000-30,000 years ago. We show that dogs are overall more closely related to ancient wolves from eastern Eurasia than to those from western Eurasia, suggesting a domestication process in the east. However, ... |
format |
Article in Journal/Newspaper |
author |
Bergström, Anders Stanton, David WG Taron, Ulrike H Frantz, Laurent Sinding, Mikkel-Holger S Ersmark, Erik Pfrengle, Saskia Cassatt-Johnstone, Molly Lebrasseur, Ophélie Girdland-Flink, Linus Fernandes, Daniel M Ollivier, Morgane Speidel, Leo Gopalakrishnan, Shyam Westbury, Michael V Ramos-Madrigal, Jazmin Feuerborn, Tatiana R Reiter, Ella Gretzinger, Joscha Münzel, Susanne C Swali, Pooja Conard, Nicholas J Carøe, Christian Haile, James Linderholm, Anna Androsov, Semyon Barnes, Ian Baumann, Chris Benecke, Norbert Bocherens, Hervé Brace, Selina Carden, Ruth F Drucker, Dorothée G Fedorov, Sergey Gasparik, Mihály Germonpré, Mietje Grigoriev, Semyon Groves, Pam Hertwig, Stefan T Ivanova, Varvara V Janssens, Luc Jennings, Richard P Kasparov, Aleksei K Kirillova, Irina V Kurmaniyazov, Islam Kuzmin, Yaroslav V Kosintsev, Pavel A Lázničková-Galetová, Martina Leduc, Charlotte Nikolskiy, Pavel |
author_facet |
Bergström, Anders Stanton, David WG Taron, Ulrike H Frantz, Laurent Sinding, Mikkel-Holger S Ersmark, Erik Pfrengle, Saskia Cassatt-Johnstone, Molly Lebrasseur, Ophélie Girdland-Flink, Linus Fernandes, Daniel M Ollivier, Morgane Speidel, Leo Gopalakrishnan, Shyam Westbury, Michael V Ramos-Madrigal, Jazmin Feuerborn, Tatiana R Reiter, Ella Gretzinger, Joscha Münzel, Susanne C Swali, Pooja Conard, Nicholas J Carøe, Christian Haile, James Linderholm, Anna Androsov, Semyon Barnes, Ian Baumann, Chris Benecke, Norbert Bocherens, Hervé Brace, Selina Carden, Ruth F Drucker, Dorothée G Fedorov, Sergey Gasparik, Mihály Germonpré, Mietje Grigoriev, Semyon Groves, Pam Hertwig, Stefan T Ivanova, Varvara V Janssens, Luc Jennings, Richard P Kasparov, Aleksei K Kirillova, Irina V Kurmaniyazov, Islam Kuzmin, Yaroslav V Kosintsev, Pavel A Lázničková-Galetová, Martina Leduc, Charlotte Nikolskiy, Pavel |
author_sort |
Bergström, Anders |
title |
Grey wolf genomic history reveals a dual ancestry of dogs. ... |
title_short |
Grey wolf genomic history reveals a dual ancestry of dogs. ... |
title_full |
Grey wolf genomic history reveals a dual ancestry of dogs. ... |
title_fullStr |
Grey wolf genomic history reveals a dual ancestry of dogs. ... |
title_full_unstemmed |
Grey wolf genomic history reveals a dual ancestry of dogs. ... |
title_sort |
grey wolf genomic history reveals a dual ancestry of dogs. ... |
publisher |
Springer Science and Business Media LLC |
publishDate |
2022 |
url |
https://dx.doi.org/10.17863/cam.87108 https://www.repository.cam.ac.uk/handle/1810/339689 |
genre |
Canis lupus Siberia |
genre_facet |
Canis lupus Siberia |
op_rights |
open.access Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 http://purl.org/coar/access_right/c_abf2 |
op_doi |
https://doi.org/10.17863/cam.87108 |
_version_ |
1792046586215268352 |