Balloon Compression Spinal Cord Injury in Animal Model Using Canine and Capra ...
Purpose: This study aims to observe the feasibility of canines and capra as large animal models for the use in SCI in vivo research. Components observed in this study include daily activity, and neurological function. Methods: This research incorporated the use of goats (Capra aegagrus hircus) and d...
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2023
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Online Access: | https://dx.doi.org/10.17632/mwytjyjd5t.1 https://data.mendeley.com/datasets/mwytjyjd5t/1 |
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ftdatacite:10.17632/mwytjyjd5t.1 2023-12-31T10:05:45+01:00 Balloon Compression Spinal Cord Injury in Animal Model Using Canine and Capra ... Sakti, Yudha Mathan 2023 https://dx.doi.org/10.17632/mwytjyjd5t.1 https://data.mendeley.com/datasets/mwytjyjd5t/1 unknown Mendeley Data https://dx.doi.org/10.17632/mwytjyjd5t Creative Commons Attribution 4.0 International info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 Spinal Cord Injury Animal Study Goat Canine Dataset dataset 2023 ftdatacite https://doi.org/10.17632/mwytjyjd5t.110.17632/mwytjyjd5t 2023-12-01T12:20:54Z Purpose: This study aims to observe the feasibility of canines and capra as large animal models for the use in SCI in vivo research. Components observed in this study include daily activity, and neurological function. Methods: This research incorporated the use of goats (Capra aegagrus hircus) and dogs (Canis lupus familiaris) as the animal model of choice due to similarities in spine and vertebral structures with humans. To stimulate SCI in animals, ballooning compression was done in animals to mimic the compression-stimulated SCI common in human. Results: The induction procedure was successfully done in all animals. Directly following the induction procedure, motoric and sensory functions were absent in all dogs and goats. Decreased physical activity was observed in goats. Compromised urinary function was observed in both goats and dogs. Both animals retained defecation function. Inflammation, hemorrhaging, and necrosis was observed in histopathological investigations. Conclusion: In our observations, the ... Dataset Canis lupus DataCite Metadata Store (German National Library of Science and Technology) |
institution |
Open Polar |
collection |
DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
ftdatacite |
language |
unknown |
topic |
Spinal Cord Injury Animal Study Goat Canine |
spellingShingle |
Spinal Cord Injury Animal Study Goat Canine Sakti, Yudha Mathan Balloon Compression Spinal Cord Injury in Animal Model Using Canine and Capra ... |
topic_facet |
Spinal Cord Injury Animal Study Goat Canine |
description |
Purpose: This study aims to observe the feasibility of canines and capra as large animal models for the use in SCI in vivo research. Components observed in this study include daily activity, and neurological function. Methods: This research incorporated the use of goats (Capra aegagrus hircus) and dogs (Canis lupus familiaris) as the animal model of choice due to similarities in spine and vertebral structures with humans. To stimulate SCI in animals, ballooning compression was done in animals to mimic the compression-stimulated SCI common in human. Results: The induction procedure was successfully done in all animals. Directly following the induction procedure, motoric and sensory functions were absent in all dogs and goats. Decreased physical activity was observed in goats. Compromised urinary function was observed in both goats and dogs. Both animals retained defecation function. Inflammation, hemorrhaging, and necrosis was observed in histopathological investigations. Conclusion: In our observations, the ... |
format |
Dataset |
author |
Sakti, Yudha Mathan |
author_facet |
Sakti, Yudha Mathan |
author_sort |
Sakti, Yudha Mathan |
title |
Balloon Compression Spinal Cord Injury in Animal Model Using Canine and Capra ... |
title_short |
Balloon Compression Spinal Cord Injury in Animal Model Using Canine and Capra ... |
title_full |
Balloon Compression Spinal Cord Injury in Animal Model Using Canine and Capra ... |
title_fullStr |
Balloon Compression Spinal Cord Injury in Animal Model Using Canine and Capra ... |
title_full_unstemmed |
Balloon Compression Spinal Cord Injury in Animal Model Using Canine and Capra ... |
title_sort |
balloon compression spinal cord injury in animal model using canine and capra ... |
publisher |
Mendeley Data |
publishDate |
2023 |
url |
https://dx.doi.org/10.17632/mwytjyjd5t.1 https://data.mendeley.com/datasets/mwytjyjd5t/1 |
genre |
Canis lupus |
genre_facet |
Canis lupus |
op_relation |
https://dx.doi.org/10.17632/mwytjyjd5t |
op_rights |
Creative Commons Attribution 4.0 International info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 |
op_doi |
https://doi.org/10.17632/mwytjyjd5t.110.17632/mwytjyjd5t |
_version_ |
1786837443783163904 |