The immune response of bats differs between pre-migration and migration seasons
Maintaining a competent immune system is energetically costly and thus immunity may be traded against other costly traits such as seasonal migration. Here, we tested in long-distance migratory Nathusius' pipistrelles (Pipistrellus nathusii), if selected branches of immunity are expressed differ...
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ftdatacite:10.17169/refubium-29043 2023-05-15T17:59:46+02:00 The immune response of bats differs between pre-migration and migration seasons Voigt, Christian C. Fritze, Marcus Lindecke, Oliver Costantini, David Petersons, Gunars Czirják, Gábor Á. 2020 https://dx.doi.org/10.17169/refubium-29043 https://refubium.fu-berlin.de/handle/fub188/29296 unknown Freie Universität Berlin https://doi.org/10.1038/s41598-020-74473-3 https://dx.doi.org/10.1038/s41598-020-74473-3 https://doi.org/10.1038/s41598-020-74473-3 Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 CC-BY oxidative stress costs immunology longevity defenses thrushes diseases flight 500 Naturwissenschaften und Mathematik570 Biowissenschaften; Biologie570 Biowissenschaften; Biologie Text article-journal Wissenschaftlicher Artikel ScholarlyArticle 2020 ftdatacite https://doi.org/10.17169/refubium-29043 https://doi.org/10.1038/s41598-020-74473-3 2021-11-05T12:55:41Z Maintaining a competent immune system is energetically costly and thus immunity may be traded against other costly traits such as seasonal migration. Here, we tested in long-distance migratory Nathusius' pipistrelles (Pipistrellus nathusii), if selected branches of immunity are expressed differently in response to the energy demands and oxidative stress of aerial migration. During the migration period, we observed higher baseline lymphocyte and lower neutrophil levels than during the pre-migration period, but no stronger response of cellular effectors to an antigen challenge. Baseline plasma haptoglobin, as a component of the humoral innate immunity, remained similar during both seasons, yet baseline plasma haptoglobin levels increased by a factor of 7.8 in migratory bats during an immune challenge, whereas they did not change during the pre-migration period. Oxidative stress was higher during migration than during pre-migration, yet there was no association between blood oxidative status and immune parameters, and immune challenge did not trigger any changes in oxidative stress, irrespective of season. Our findings suggest that humoral effectors of the acute phase response may play a stronger role in the first-line defense against infections for migrating bats compared to non-migrating bats. We conclude that Nathusius' pipistrelles allocate resources differently into the branches of their immune system, most likely following current demands resulting from tight energy budgets during migration. Text Pipistrellus nathusii DataCite Metadata Store (German National Library of Science and Technology) |
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DataCite Metadata Store (German National Library of Science and Technology) |
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topic |
oxidative stress costs immunology longevity defenses thrushes diseases flight 500 Naturwissenschaften und Mathematik570 Biowissenschaften; Biologie570 Biowissenschaften; Biologie |
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oxidative stress costs immunology longevity defenses thrushes diseases flight 500 Naturwissenschaften und Mathematik570 Biowissenschaften; Biologie570 Biowissenschaften; Biologie Voigt, Christian C. Fritze, Marcus Lindecke, Oliver Costantini, David Petersons, Gunars Czirják, Gábor Á. The immune response of bats differs between pre-migration and migration seasons |
topic_facet |
oxidative stress costs immunology longevity defenses thrushes diseases flight 500 Naturwissenschaften und Mathematik570 Biowissenschaften; Biologie570 Biowissenschaften; Biologie |
description |
Maintaining a competent immune system is energetically costly and thus immunity may be traded against other costly traits such as seasonal migration. Here, we tested in long-distance migratory Nathusius' pipistrelles (Pipistrellus nathusii), if selected branches of immunity are expressed differently in response to the energy demands and oxidative stress of aerial migration. During the migration period, we observed higher baseline lymphocyte and lower neutrophil levels than during the pre-migration period, but no stronger response of cellular effectors to an antigen challenge. Baseline plasma haptoglobin, as a component of the humoral innate immunity, remained similar during both seasons, yet baseline plasma haptoglobin levels increased by a factor of 7.8 in migratory bats during an immune challenge, whereas they did not change during the pre-migration period. Oxidative stress was higher during migration than during pre-migration, yet there was no association between blood oxidative status and immune parameters, and immune challenge did not trigger any changes in oxidative stress, irrespective of season. Our findings suggest that humoral effectors of the acute phase response may play a stronger role in the first-line defense against infections for migrating bats compared to non-migrating bats. We conclude that Nathusius' pipistrelles allocate resources differently into the branches of their immune system, most likely following current demands resulting from tight energy budgets during migration. |
format |
Text |
author |
Voigt, Christian C. Fritze, Marcus Lindecke, Oliver Costantini, David Petersons, Gunars Czirják, Gábor Á. |
author_facet |
Voigt, Christian C. Fritze, Marcus Lindecke, Oliver Costantini, David Petersons, Gunars Czirják, Gábor Á. |
author_sort |
Voigt, Christian C. |
title |
The immune response of bats differs between pre-migration and migration seasons |
title_short |
The immune response of bats differs between pre-migration and migration seasons |
title_full |
The immune response of bats differs between pre-migration and migration seasons |
title_fullStr |
The immune response of bats differs between pre-migration and migration seasons |
title_full_unstemmed |
The immune response of bats differs between pre-migration and migration seasons |
title_sort |
immune response of bats differs between pre-migration and migration seasons |
publisher |
Freie Universität Berlin |
publishDate |
2020 |
url |
https://dx.doi.org/10.17169/refubium-29043 https://refubium.fu-berlin.de/handle/fub188/29296 |
genre |
Pipistrellus nathusii |
genre_facet |
Pipistrellus nathusii |
op_relation |
https://doi.org/10.1038/s41598-020-74473-3 https://dx.doi.org/10.1038/s41598-020-74473-3 https://doi.org/10.1038/s41598-020-74473-3 |
op_rights |
Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.17169/refubium-29043 https://doi.org/10.1038/s41598-020-74473-3 |
_version_ |
1766168644036853760 |