Benzo[a]pyrene exposure under future ocean acidification scenarios weakens the immune responses of blood clam, Tegillarca granosa ...

• Main Authors: Su, Wenhao, Zha, Shanjie, Wang, Yichen, Shi, Wei, Xiao, Guoqiang, Chai, Xueliang, Wu, Hongxi, Liu, Guangxu
• Format: Dataset
• Language: English
• Published: PANGAEA 2017
• Subjects: Animalia; Benthic animals; Benthos; Brackish waters; Containers and aquaria 20-1000 L or < 1 m**2; Gene expression incl. proteomics; Immunology/Self-protection; Laboratory experiment; Mollusca; North Pacific; Organic toxins; Single species; Tegillarca granosa; Temperate; Type; Species; Registration number of species; Uniform resource locator/link to reference; Experiment duration; Figure; Mass; Mass, standard error; Tissues; Date; Treatment; Gene expression; Gene expression, standard error; pH; pH, standard deviation; Partial pressure of carbon dioxide water at sea surface temperature wet air; Partial pressure of carbon dioxide, standard deviation; Salinity; Salinity, standard deviation; Temperature, water; Temperature, water, standard deviation; Alkalinity, total; Alkalinity, total, standard deviation; Carbon, inorganic, dissolved; Carbon, inorganic, dissolved, standard error; Aragonite saturation state; Aragonite saturation state, standard deviation; Calcite saturation state; Calcite saturation state, standard deviation; Hemocyte count; Hemocyte count, standard error; Granulocyte, red; Granulocyte, red, standard error; Granulocyte, basophil; Granulocyte, basophil, standard error; Hyalinocyte; Pacific; Ocean acidification
• Online Access: https://dx.doi.org/10.1594/pangaea.875000; https://doi.pangaea.de/10.1594/PANGAEA.875000

Persistent organic pollutants (POPs) are known to converge into the ocean and accumulate in the sediment, posing great threats to marine organisms such as the sessile bottom burrowing bivalves. However, the immune toxicity of POPs, such as B[a]P, under future ocean acidification scenarios remains poorly understood to date. Therefore, in the present study, the impacts of B[a]P exposure on the immune responses of a bivalve species, Tegillarca granosa, under present and future ocean acidification scenarios were investigated. Results obtained revealed an increased immune toxicity of B[a]P under future ocean acidification scenarios in terms of reduced THC, altered haemocyte composition, and hampered phagocytosis, which may attribute to the synergetic effects of B[a]P and ocean acidification. In addition, the gene expressions of pathogen pattern recognition receptors (TLR1, TLR2, TLR4, TLR6), pathway mediators (TRAF6, TAK1, TAB2, IKKalpha and Myd88), and effectors (NF-kB) of the important immune related pathways ... : In order to allow full comparability with other ocean acidification data sets, the R package seacarb (Gattuso et al, 2016) was used to compute a complete and consistent set of carbonate system variables, as described by Nisumaa et al. (2010). In this dataset the original values were archived in addition with the recalculated parameters (see related PI). The date of carbonate chemistry calculation by seacarb is 2017-04-26. ...