(Table 2) Mercury and selenium concentration in the brain stem of wild polar bears (Ursus maritimus), east Greenland, supplement to: Basu, Niladri; Scheuhammer, Anton M; Sonne, Christian; Letcher, Robert J; Born, Erik W; Dietz, Rune (2009): Is dietary mercury of neurotoxicological concern to wild polar bears (Ursus maritimus)? Environmental Toxicology and Chemistry, 28(1), 133-140
Polar bears (Ursus maritimus) are exposed to high concentrations of mercury because they are apex predators in the Arctic ecosystem. Although mercury is a potent neurotoxic heavy metal, it is not known whether current exposures are of neurotoxicological concern to polar bears. We tested the hypothes...
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Online Access: | https://dx.doi.org/10.1594/pangaea.807159 https://doi.pangaea.de/10.1594/PANGAEA.807159 |
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ftdatacite:10.1594/pangaea.807159 2023-05-15T15:16:02+02:00 (Table 2) Mercury and selenium concentration in the brain stem of wild polar bears (Ursus maritimus), east Greenland, supplement to: Basu, Niladri; Scheuhammer, Anton M; Sonne, Christian; Letcher, Robert J; Born, Erik W; Dietz, Rune (2009): Is dietary mercury of neurotoxicological concern to wild polar bears (Ursus maritimus)? Environmental Toxicology and Chemistry, 28(1), 133-140 Basu, Niladri Scheuhammer, Anton M Sonne, Christian Letcher, Robert J Born, Erik W Dietz, Rune 2009 text/tab-separated-values https://dx.doi.org/10.1594/pangaea.807159 https://doi.pangaea.de/10.1594/PANGAEA.807159 en eng PANGAEA - Data Publisher for Earth & Environmental Science https://dx.doi.org/10.1897/08-251.1 Creative Commons Attribution 3.0 Unported https://creativecommons.org/licenses/by/3.0/legalcode cc-by-3.0 CC-BY Category Parameter Sample amount Mercury Mercury, standard deviation Selenium Selenium, standard deviation Ratio Standard deviation Biological sample Advanced Mercury Analyser AMA-254, LECO International Polar Year 2007-2008 IPY Supplementary Dataset dataset Dataset 2009 ftdatacite https://doi.org/10.1594/pangaea.807159 https://doi.org/10.1897/08-251.1 2021-11-05T12:55:41Z Polar bears (Ursus maritimus) are exposed to high concentrations of mercury because they are apex predators in the Arctic ecosystem. Although mercury is a potent neurotoxic heavy metal, it is not known whether current exposures are of neurotoxicological concern to polar bears. We tested the hypotheses that polar bears accumulate levels of mercury in their brains that exceed the estimated lowest observable adverse effect level (20 µg/g dry wt) for mammalian wildlife and that such exposures are associated with subtle neurological damage, as determined by measuring neurochemical biomarkers previously shown to be disrupted by mercury in other high-trophic wildlife. Brain stem (medulla oblongata) tissues from 82 polar bears subsistence hunted in East Greenland were studied. Despite surprisingly low levels of mercury in the brain stem region (total mercury = 0.36 ± 0.12 µg/g dry wt), a significant negative correlation was measured between N-methyl-D-aspartate (NMDA) receptor levels and both total mercury (r = -0.34, p < 0.01) and methylmercury (r = -0.89, p < 0.05). No relationships were observed among mercury, selenium, and several other neurochemical biomarkers (dopamine-2, gamma-aminobutyric acid type A, muscarinic cholinergic, and nicotinic cholinergic receptors; cholinesterase and monoamine oxidase enzymes). These data show that East Greenland polar bears do not accumulate high levels of mercury in their brain stems. However, decreased levels of NMDA receptors could be one of the most sensitive indicators of mercury's subclinical and early effects. : Data extracted in the frame of a joint ICSTI/PANGAEA IPY effort, see http://doi.pangaea.de/10.1594/PANGAEA.150150 Dataset Arctic East Greenland Greenland International Polar Year IPY Ursus maritimus DataCite Metadata Store (German National Library of Science and Technology) Arctic Dietz ENVELOPE(-153.167,-153.167,-86.267,-86.267) Greenland |
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Open Polar |
collection |
DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
ftdatacite |
language |
English |
topic |
Category Parameter Sample amount Mercury Mercury, standard deviation Selenium Selenium, standard deviation Ratio Standard deviation Biological sample Advanced Mercury Analyser AMA-254, LECO International Polar Year 2007-2008 IPY |
spellingShingle |
Category Parameter Sample amount Mercury Mercury, standard deviation Selenium Selenium, standard deviation Ratio Standard deviation Biological sample Advanced Mercury Analyser AMA-254, LECO International Polar Year 2007-2008 IPY Basu, Niladri Scheuhammer, Anton M Sonne, Christian Letcher, Robert J Born, Erik W Dietz, Rune (Table 2) Mercury and selenium concentration in the brain stem of wild polar bears (Ursus maritimus), east Greenland, supplement to: Basu, Niladri; Scheuhammer, Anton M; Sonne, Christian; Letcher, Robert J; Born, Erik W; Dietz, Rune (2009): Is dietary mercury of neurotoxicological concern to wild polar bears (Ursus maritimus)? Environmental Toxicology and Chemistry, 28(1), 133-140 |
topic_facet |
Category Parameter Sample amount Mercury Mercury, standard deviation Selenium Selenium, standard deviation Ratio Standard deviation Biological sample Advanced Mercury Analyser AMA-254, LECO International Polar Year 2007-2008 IPY |
description |
Polar bears (Ursus maritimus) are exposed to high concentrations of mercury because they are apex predators in the Arctic ecosystem. Although mercury is a potent neurotoxic heavy metal, it is not known whether current exposures are of neurotoxicological concern to polar bears. We tested the hypotheses that polar bears accumulate levels of mercury in their brains that exceed the estimated lowest observable adverse effect level (20 µg/g dry wt) for mammalian wildlife and that such exposures are associated with subtle neurological damage, as determined by measuring neurochemical biomarkers previously shown to be disrupted by mercury in other high-trophic wildlife. Brain stem (medulla oblongata) tissues from 82 polar bears subsistence hunted in East Greenland were studied. Despite surprisingly low levels of mercury in the brain stem region (total mercury = 0.36 ± 0.12 µg/g dry wt), a significant negative correlation was measured between N-methyl-D-aspartate (NMDA) receptor levels and both total mercury (r = -0.34, p < 0.01) and methylmercury (r = -0.89, p < 0.05). No relationships were observed among mercury, selenium, and several other neurochemical biomarkers (dopamine-2, gamma-aminobutyric acid type A, muscarinic cholinergic, and nicotinic cholinergic receptors; cholinesterase and monoamine oxidase enzymes). These data show that East Greenland polar bears do not accumulate high levels of mercury in their brain stems. However, decreased levels of NMDA receptors could be one of the most sensitive indicators of mercury's subclinical and early effects. : Data extracted in the frame of a joint ICSTI/PANGAEA IPY effort, see http://doi.pangaea.de/10.1594/PANGAEA.150150 |
format |
Dataset |
author |
Basu, Niladri Scheuhammer, Anton M Sonne, Christian Letcher, Robert J Born, Erik W Dietz, Rune |
author_facet |
Basu, Niladri Scheuhammer, Anton M Sonne, Christian Letcher, Robert J Born, Erik W Dietz, Rune |
author_sort |
Basu, Niladri |
title |
(Table 2) Mercury and selenium concentration in the brain stem of wild polar bears (Ursus maritimus), east Greenland, supplement to: Basu, Niladri; Scheuhammer, Anton M; Sonne, Christian; Letcher, Robert J; Born, Erik W; Dietz, Rune (2009): Is dietary mercury of neurotoxicological concern to wild polar bears (Ursus maritimus)? Environmental Toxicology and Chemistry, 28(1), 133-140 |
title_short |
(Table 2) Mercury and selenium concentration in the brain stem of wild polar bears (Ursus maritimus), east Greenland, supplement to: Basu, Niladri; Scheuhammer, Anton M; Sonne, Christian; Letcher, Robert J; Born, Erik W; Dietz, Rune (2009): Is dietary mercury of neurotoxicological concern to wild polar bears (Ursus maritimus)? Environmental Toxicology and Chemistry, 28(1), 133-140 |
title_full |
(Table 2) Mercury and selenium concentration in the brain stem of wild polar bears (Ursus maritimus), east Greenland, supplement to: Basu, Niladri; Scheuhammer, Anton M; Sonne, Christian; Letcher, Robert J; Born, Erik W; Dietz, Rune (2009): Is dietary mercury of neurotoxicological concern to wild polar bears (Ursus maritimus)? Environmental Toxicology and Chemistry, 28(1), 133-140 |
title_fullStr |
(Table 2) Mercury and selenium concentration in the brain stem of wild polar bears (Ursus maritimus), east Greenland, supplement to: Basu, Niladri; Scheuhammer, Anton M; Sonne, Christian; Letcher, Robert J; Born, Erik W; Dietz, Rune (2009): Is dietary mercury of neurotoxicological concern to wild polar bears (Ursus maritimus)? Environmental Toxicology and Chemistry, 28(1), 133-140 |
title_full_unstemmed |
(Table 2) Mercury and selenium concentration in the brain stem of wild polar bears (Ursus maritimus), east Greenland, supplement to: Basu, Niladri; Scheuhammer, Anton M; Sonne, Christian; Letcher, Robert J; Born, Erik W; Dietz, Rune (2009): Is dietary mercury of neurotoxicological concern to wild polar bears (Ursus maritimus)? Environmental Toxicology and Chemistry, 28(1), 133-140 |
title_sort |
(table 2) mercury and selenium concentration in the brain stem of wild polar bears (ursus maritimus), east greenland, supplement to: basu, niladri; scheuhammer, anton m; sonne, christian; letcher, robert j; born, erik w; dietz, rune (2009): is dietary mercury of neurotoxicological concern to wild polar bears (ursus maritimus)? environmental toxicology and chemistry, 28(1), 133-140 |
publisher |
PANGAEA - Data Publisher for Earth & Environmental Science |
publishDate |
2009 |
url |
https://dx.doi.org/10.1594/pangaea.807159 https://doi.pangaea.de/10.1594/PANGAEA.807159 |
long_lat |
ENVELOPE(-153.167,-153.167,-86.267,-86.267) |
geographic |
Arctic Dietz Greenland |
geographic_facet |
Arctic Dietz Greenland |
genre |
Arctic East Greenland Greenland International Polar Year IPY Ursus maritimus |
genre_facet |
Arctic East Greenland Greenland International Polar Year IPY Ursus maritimus |
op_relation |
https://dx.doi.org/10.1897/08-251.1 |
op_rights |
Creative Commons Attribution 3.0 Unported https://creativecommons.org/licenses/by/3.0/legalcode cc-by-3.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1594/pangaea.807159 https://doi.org/10.1897/08-251.1 |
_version_ |
1766346353274781696 |