PAH/PFAS mixture toxicity in vivo
BERGEN PUBLICATION Location: UiB Duration: 14 days, injections at day 0 and day 7 Sampling dates: 29-30 March 2017 Compounds tested: Polycyclic aromatic hydrocarbons (PAHs)/ Per- and polyfluoroalkyl substances (PFAS) No. of test groups: 10 No. of fish per group: 21-22 No. of dead fish: Aim: *To inve...
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ftdatacite:10.15490/fairdomhub.1.study.753.1 2023-05-15T15:27:23+02:00 PAH/PFAS mixture toxicity in vivo Dale, Karina 2020 https://dx.doi.org/10.15490/fairdomhub.1.study.753.1 https://fairdomhub.org/studies/753/snapshots/1 unknown FAIRDOMHub Collection article Study 2020 ftdatacite https://doi.org/10.15490/fairdomhub.1.study.753.1 2021-11-05T12:55:41Z BERGEN PUBLICATION Location: UiB Duration: 14 days, injections at day 0 and day 7 Sampling dates: 29-30 March 2017 Compounds tested: Polycyclic aromatic hydrocarbons (PAHs)/ Per- and polyfluoroalkyl substances (PFAS) No. of test groups: 10 No. of fish per group: 21-22 No. of dead fish: Aim: *To investigate biological responses in Atlantic cod ( Gadus morhua) after in vivo exposure to a mixture of PAHs and PFASs, either singly or combined, at low (1x) or high (20x) doses. *PFAS concentrations were determined in cod liver, and PAH metabolites were measured in bile as a biomarker of PAH exposure. *Various biomarkers were determined at transcript and protein levels in the liver, and lipidomics and proteomics analyses were performed on liver tissue to study responses on lipid metabolism. Report atlantic cod Gadus morhua DataCite Metadata Store (German National Library of Science and Technology) Bergen |
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DataCite Metadata Store (German National Library of Science and Technology) |
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ftdatacite |
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description |
BERGEN PUBLICATION Location: UiB Duration: 14 days, injections at day 0 and day 7 Sampling dates: 29-30 March 2017 Compounds tested: Polycyclic aromatic hydrocarbons (PAHs)/ Per- and polyfluoroalkyl substances (PFAS) No. of test groups: 10 No. of fish per group: 21-22 No. of dead fish: Aim: *To investigate biological responses in Atlantic cod ( Gadus morhua) after in vivo exposure to a mixture of PAHs and PFASs, either singly or combined, at low (1x) or high (20x) doses. *PFAS concentrations were determined in cod liver, and PAH metabolites were measured in bile as a biomarker of PAH exposure. *Various biomarkers were determined at transcript and protein levels in the liver, and lipidomics and proteomics analyses were performed on liver tissue to study responses on lipid metabolism. |
format |
Report |
author |
Dale, Karina |
spellingShingle |
Dale, Karina PAH/PFAS mixture toxicity in vivo |
author_facet |
Dale, Karina |
author_sort |
Dale, Karina |
title |
PAH/PFAS mixture toxicity in vivo |
title_short |
PAH/PFAS mixture toxicity in vivo |
title_full |
PAH/PFAS mixture toxicity in vivo |
title_fullStr |
PAH/PFAS mixture toxicity in vivo |
title_full_unstemmed |
PAH/PFAS mixture toxicity in vivo |
title_sort |
pah/pfas mixture toxicity in vivo |
publisher |
FAIRDOMHub |
publishDate |
2020 |
url |
https://dx.doi.org/10.15490/fairdomhub.1.study.753.1 https://fairdomhub.org/studies/753/snapshots/1 |
geographic |
Bergen |
geographic_facet |
Bergen |
genre |
atlantic cod Gadus morhua |
genre_facet |
atlantic cod Gadus morhua |
op_doi |
https://doi.org/10.15490/fairdomhub.1.study.753.1 |
_version_ |
1766357832131674112 |