PAH/PFAS mixture toxicity in vivo

BERGEN PUBLICATION Location: UiB Duration: 14 days, injections at day 0 and day 7 Sampling dates: 29-30 March 2017 Compounds tested: Polycyclic aromatic hydrocarbons (PAHs)/ Per- and polyfluoroalkyl substances (PFAS) No. of test groups: 10 No. of fish per group: 21-22 No. of dead fish: Aim: *To inve...

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Bibliographic Details
Main Author: Dale, Karina
Format: Report
Language:unknown
Published: FAIRDOMHub 2020
Subjects:
Bergen
atlantic cod
Gadus morhua
Online Access:https://dx.doi.org/10.15490/fairdomhub.1.study.753.1
https://fairdomhub.org/studies/753/snapshots/1
id ftdatacite:10.15490/fairdomhub.1.study.753.1
record_format openpolar
spelling ftdatacite:10.15490/fairdomhub.1.study.753.1 2023-05-15T15:27:23+02:00 PAH/PFAS mixture toxicity in vivo Dale, Karina 2020 https://dx.doi.org/10.15490/fairdomhub.1.study.753.1 https://fairdomhub.org/studies/753/snapshots/1 unknown FAIRDOMHub Collection article Study 2020 ftdatacite https://doi.org/10.15490/fairdomhub.1.study.753.1 2021-11-05T12:55:41Z BERGEN PUBLICATION Location: UiB Duration: 14 days, injections at day 0 and day 7 Sampling dates: 29-30 March 2017 Compounds tested: Polycyclic aromatic hydrocarbons (PAHs)/ Per- and polyfluoroalkyl substances (PFAS) No. of test groups: 10 No. of fish per group: 21-22 No. of dead fish: Aim: *To investigate biological responses in Atlantic cod ( Gadus morhua) after in vivo exposure to a mixture of PAHs and PFASs, either singly or combined, at low (1x) or high (20x) doses. *PFAS concentrations were determined in cod liver, and PAH metabolites were measured in bile as a biomarker of PAH exposure. *Various biomarkers were determined at transcript and protein levels in the liver, and lipidomics and proteomics analyses were performed on liver tissue to study responses on lipid metabolism. Report atlantic cod Gadus morhua DataCite Metadata Store (German National Library of Science and Technology) Bergen
institution Open Polar
collection DataCite Metadata Store (German National Library of Science and Technology)
op_collection_id ftdatacite
language unknown
description BERGEN PUBLICATION Location: UiB Duration: 14 days, injections at day 0 and day 7 Sampling dates: 29-30 March 2017 Compounds tested: Polycyclic aromatic hydrocarbons (PAHs)/ Per- and polyfluoroalkyl substances (PFAS) No. of test groups: 10 No. of fish per group: 21-22 No. of dead fish: Aim: *To investigate biological responses in Atlantic cod ( Gadus morhua) after in vivo exposure to a mixture of PAHs and PFASs, either singly or combined, at low (1x) or high (20x) doses. *PFAS concentrations were determined in cod liver, and PAH metabolites were measured in bile as a biomarker of PAH exposure. *Various biomarkers were determined at transcript and protein levels in the liver, and lipidomics and proteomics analyses were performed on liver tissue to study responses on lipid metabolism.
format Report
author Dale, Karina
spellingShingle Dale, Karina
PAH/PFAS mixture toxicity in vivo
author_facet Dale, Karina
author_sort Dale, Karina
title PAH/PFAS mixture toxicity in vivo
title_short PAH/PFAS mixture toxicity in vivo
title_full PAH/PFAS mixture toxicity in vivo
title_fullStr PAH/PFAS mixture toxicity in vivo
title_full_unstemmed PAH/PFAS mixture toxicity in vivo
title_sort pah/pfas mixture toxicity in vivo
publisher FAIRDOMHub
publishDate 2020
url https://dx.doi.org/10.15490/fairdomhub.1.study.753.1
https://fairdomhub.org/studies/753/snapshots/1
geographic Bergen
geographic_facet Bergen
genre atlantic cod
Gadus morhua
genre_facet atlantic cod
Gadus morhua
op_doi https://doi.org/10.15490/fairdomhub.1.study.753.1
_version_ 1766357832131674112

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