The Genome of the North American Brown Bear or Grizzly: Ursus arctos ssp. horribilis ...
The grizzly bear (Ursus arctos ssp. horribilis) represents the largest population of brown bears in North America. Its genome was sequenced using a microfluidic partitioning library construction technique, and these data were supplemented with sequencing from a nanopore-based long read platform. The...
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ftdatacite:10.14288/1.0379352 2024-04-28T08:41:02+00:00 The Genome of the North American Brown Bear or Grizzly: Ursus arctos ssp. horribilis ... Taylor, Gregory A. Kirk, Heather Coombe, Lauren Jackman, Shaun D. Chu, Justin Tse, Kane Cheng, Dean Chuah, Eric Pandoh, Pawan Carlsen, Rebecca Zhao, Yongjun Mungall, Andrew J. Moore, Richard Birol, Inanc Franke, Maria Marra, Marco, 1966- Dutton, Christopher Jones, Steven J. M. 2019 https://dx.doi.org/10.14288/1.0379352 https://doi.library.ubc.ca/10.14288/1.0379352 en eng Multidisciplinary Digital Publishing Institute https://dx.doi.org/10.3390/genes9120598 article-journal Text ScholarlyArticle 2019 ftdatacite https://doi.org/10.14288/1.037935210.3390/genes9120598 2024-04-02T09:53:47Z The grizzly bear (Ursus arctos ssp. horribilis) represents the largest population of brown bears in North America. Its genome was sequenced using a microfluidic partitioning library construction technique, and these data were supplemented with sequencing from a nanopore-based long read platform. The final assembly was 2.33 Gb with a scaffold N50 of 36.7 Mb, and the genome is of comparable size to that of its close relative the polar bear (2.30 Gb). An analysis using 4104 highly conserved mammalian genes indicated that 96.1% were found to be complete within the assembly. An automated annotation of the genome identified 19,848 protein coding genes. Our study shows that the combination of the two sequencing modalities that we used is sufficient for the construction of highly contiguous reference quality mammalian genomes. The assembled genome sequence and the supporting raw sequence reads are available from the NCBI (National Center for Biotechnology Information) under the bioproject identifier PRJNA493656, and ... Text Ursus arctos DataCite Metadata Store (German National Library of Science and Technology) |
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Open Polar |
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DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
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English |
description |
The grizzly bear (Ursus arctos ssp. horribilis) represents the largest population of brown bears in North America. Its genome was sequenced using a microfluidic partitioning library construction technique, and these data were supplemented with sequencing from a nanopore-based long read platform. The final assembly was 2.33 Gb with a scaffold N50 of 36.7 Mb, and the genome is of comparable size to that of its close relative the polar bear (2.30 Gb). An analysis using 4104 highly conserved mammalian genes indicated that 96.1% were found to be complete within the assembly. An automated annotation of the genome identified 19,848 protein coding genes. Our study shows that the combination of the two sequencing modalities that we used is sufficient for the construction of highly contiguous reference quality mammalian genomes. The assembled genome sequence and the supporting raw sequence reads are available from the NCBI (National Center for Biotechnology Information) under the bioproject identifier PRJNA493656, and ... |
format |
Text |
author |
Taylor, Gregory A. Kirk, Heather Coombe, Lauren Jackman, Shaun D. Chu, Justin Tse, Kane Cheng, Dean Chuah, Eric Pandoh, Pawan Carlsen, Rebecca Zhao, Yongjun Mungall, Andrew J. Moore, Richard Birol, Inanc Franke, Maria Marra, Marco, 1966- Dutton, Christopher Jones, Steven J. M. |
spellingShingle |
Taylor, Gregory A. Kirk, Heather Coombe, Lauren Jackman, Shaun D. Chu, Justin Tse, Kane Cheng, Dean Chuah, Eric Pandoh, Pawan Carlsen, Rebecca Zhao, Yongjun Mungall, Andrew J. Moore, Richard Birol, Inanc Franke, Maria Marra, Marco, 1966- Dutton, Christopher Jones, Steven J. M. The Genome of the North American Brown Bear or Grizzly: Ursus arctos ssp. horribilis ... |
author_facet |
Taylor, Gregory A. Kirk, Heather Coombe, Lauren Jackman, Shaun D. Chu, Justin Tse, Kane Cheng, Dean Chuah, Eric Pandoh, Pawan Carlsen, Rebecca Zhao, Yongjun Mungall, Andrew J. Moore, Richard Birol, Inanc Franke, Maria Marra, Marco, 1966- Dutton, Christopher Jones, Steven J. M. |
author_sort |
Taylor, Gregory A. |
title |
The Genome of the North American Brown Bear or Grizzly: Ursus arctos ssp. horribilis ... |
title_short |
The Genome of the North American Brown Bear or Grizzly: Ursus arctos ssp. horribilis ... |
title_full |
The Genome of the North American Brown Bear or Grizzly: Ursus arctos ssp. horribilis ... |
title_fullStr |
The Genome of the North American Brown Bear or Grizzly: Ursus arctos ssp. horribilis ... |
title_full_unstemmed |
The Genome of the North American Brown Bear or Grizzly: Ursus arctos ssp. horribilis ... |
title_sort |
genome of the north american brown bear or grizzly: ursus arctos ssp. horribilis ... |
publisher |
Multidisciplinary Digital Publishing Institute |
publishDate |
2019 |
url |
https://dx.doi.org/10.14288/1.0379352 https://doi.library.ubc.ca/10.14288/1.0379352 |
genre |
Ursus arctos |
genre_facet |
Ursus arctos |
op_relation |
https://dx.doi.org/10.3390/genes9120598 |
op_doi |
https://doi.org/10.14288/1.037935210.3390/genes9120598 |
_version_ |
1797571452397944832 |