Biochemical studies on the expression of overdominance at the phosphoglucomutase-2 locus in the Pacific oyster, Crassostrea gigas (Thunberg) ...
Numerous studies have documented significant associations between multiple-locus heterozygosity and fitness-related traits in natural populations, but the explanations for these patterns remain unknown. The objective of the present study was to examine the merits of the overdominance hypothesis as t...
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ftdatacite:10.14288/1.0098360 2024-04-28T08:16:24+00:00 Biochemical studies on the expression of overdominance at the phosphoglucomutase-2 locus in the Pacific oyster, Crassostrea gigas (Thunberg) ... Pogson, Grant H. 2010 https://dx.doi.org/10.14288/1.0098360 https://doi.library.ubc.ca/10.14288/1.0098360 en eng University of British Columbia article-journal Text ScholarlyArticle 2010 ftdatacite https://doi.org/10.14288/1.0098360 2024-04-02T09:39:20Z Numerous studies have documented significant associations between multiple-locus heterozygosity and fitness-related traits in natural populations, but the explanations for these patterns remain unknown. The objective of the present study was to examine the merits of the overdominance hypothesis as the mechanism responsible for a positive correlation between adult body weight and heterozygosity involving the phosphoglucomutase-2 (Pgm-2) locus in the Pacific oyster, Crassostrea gigas. The kinetic and structural properties of seven Pgm-2 genotypes were examined over physiological ranges of temperature and pH. Significant differences were detected between Pgm-2 genotypes in a variety of enzymic parameters, but these were largely confined to genotypes possessing the Pgm-2-92 allele, and heterozygotes displayed strict intermediacy for all functional and structural properties examined. The expression of marginal overdominance at the Pgm-2 locus was considered unlikely because of the limited scope of the observed ... Text Crassostrea gigas Pacific oyster DataCite Metadata Store (German National Library of Science and Technology) |
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DataCite Metadata Store (German National Library of Science and Technology) |
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English |
description |
Numerous studies have documented significant associations between multiple-locus heterozygosity and fitness-related traits in natural populations, but the explanations for these patterns remain unknown. The objective of the present study was to examine the merits of the overdominance hypothesis as the mechanism responsible for a positive correlation between adult body weight and heterozygosity involving the phosphoglucomutase-2 (Pgm-2) locus in the Pacific oyster, Crassostrea gigas. The kinetic and structural properties of seven Pgm-2 genotypes were examined over physiological ranges of temperature and pH. Significant differences were detected between Pgm-2 genotypes in a variety of enzymic parameters, but these were largely confined to genotypes possessing the Pgm-2-92 allele, and heterozygotes displayed strict intermediacy for all functional and structural properties examined. The expression of marginal overdominance at the Pgm-2 locus was considered unlikely because of the limited scope of the observed ... |
format |
Text |
author |
Pogson, Grant H. |
spellingShingle |
Pogson, Grant H. Biochemical studies on the expression of overdominance at the phosphoglucomutase-2 locus in the Pacific oyster, Crassostrea gigas (Thunberg) ... |
author_facet |
Pogson, Grant H. |
author_sort |
Pogson, Grant H. |
title |
Biochemical studies on the expression of overdominance at the phosphoglucomutase-2 locus in the Pacific oyster, Crassostrea gigas (Thunberg) ... |
title_short |
Biochemical studies on the expression of overdominance at the phosphoglucomutase-2 locus in the Pacific oyster, Crassostrea gigas (Thunberg) ... |
title_full |
Biochemical studies on the expression of overdominance at the phosphoglucomutase-2 locus in the Pacific oyster, Crassostrea gigas (Thunberg) ... |
title_fullStr |
Biochemical studies on the expression of overdominance at the phosphoglucomutase-2 locus in the Pacific oyster, Crassostrea gigas (Thunberg) ... |
title_full_unstemmed |
Biochemical studies on the expression of overdominance at the phosphoglucomutase-2 locus in the Pacific oyster, Crassostrea gigas (Thunberg) ... |
title_sort |
biochemical studies on the expression of overdominance at the phosphoglucomutase-2 locus in the pacific oyster, crassostrea gigas (thunberg) ... |
publisher |
University of British Columbia |
publishDate |
2010 |
url |
https://dx.doi.org/10.14288/1.0098360 https://doi.library.ubc.ca/10.14288/1.0098360 |
genre |
Crassostrea gigas Pacific oyster |
genre_facet |
Crassostrea gigas Pacific oyster |
op_doi |
https://doi.org/10.14288/1.0098360 |
_version_ |
1797581551294218240 |