Uptake and depuration of the antibiotics, oxytetracycline and Romet-30 in the Pacific oyster, Crassostrea gigas (Thunberg) ...

• Main Author: Jones, Trevor O.
• Format: Text
• Language: English
• Published: University of British Columbia 2010
• Subjects: Crassostrea gigas; Pacific oyster
• Online Access: https://dx.doi.org/10.14288/1.0098133; https://doi.library.ubc.ca/10.14288/1.0098133

Use of antibiotics in the aquaculture industry for the control of bacterial infections in salmon has led to public concern regarding antibiotic residues in salmon tissue and the potential health risk this poses to humans. Oxytetracycline and Romet-30 are two common antibacterial agents utilized to control disease in the local finfish aquaculture industry of British Columbia, Canada. Many fish farms in British Columbia are located within close proximity to existing shellfish stocks. The potential for antibiotic bioconcentration and the production of bacterial resistance to the drugs in bivalves is a concern. The development of a solid phase extraction technique for these two drugs from Pacific oysters, Crassostrea gigas was accomplished. Analysis of whole oysters via HPLC revealed detectable levels of oxytetracycline and Romet-30 up to 4 weeks after antibiotic treatment at the salmon farm site. Oysters suspended in the salmon net pens and surrounding waters were sampled over a 5 month period. Concentration of ...