The city of Yakutsk: a case of study for human brown adipose tissue in extremely cold conditions ...
The discovery of the presence of functional brown adipose tissue (BAT) also in healthy humans [1-3] has focused the attention of the scientific community on the possibility to expand body BAT content as a therapeutic strategy for the treatment and prevention of obesity and the associated metabolic d...
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Italian Journal of Anatomy and Embryology
2015
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Online Access: | https://dx.doi.org/10.13128/ijae-16910 http://www.fupress.net/index.php/ijae/article/view/16910/15805 |
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ftdatacite:10.13128/ijae-16910 2023-08-27T04:12:30+02:00 The city of Yakutsk: a case of study for human brown adipose tissue in extremely cold conditions ... Severi, Ilenia Innokentevich, Tomskii Mikhail Gavrilievich, Tikhonov Dmitrii Savvichna, Loskutova Kiunniai Andreevich, Isakov Evgeny Giordano, Antonio Gesuita, Rosaria Cinti, Saverio 2015 application/pdf https://dx.doi.org/10.13128/ijae-16910 http://www.fupress.net/index.php/ijae/article/view/16910/15805 en eng Italian Journal of Anatomy and Embryology https://dx.doi.org/10.13128/ijae-16910 Brown adipose tissue; white adipose tissue; obesity; diabetes; low temperature Text article-journal Article ScholarlyArticle 2015 ftdatacite https://doi.org/10.13128/ijae-1691010.13128/ijae-16910 2023-08-07T14:24:23Z The discovery of the presence of functional brown adipose tissue (BAT) also in healthy humans [1-3] has focused the attention of the scientific community on the possibility to expand body BAT content as a therapeutic strategy for the treatment and prevention of obesity and the associated metabolic disorders. Indeed, white-to- brown adipocyte transdifferentiation, leading to “browning” of the adipose organ, has been shown to reduce body weight and improve metabolic parameters in obese and insulin-resistant animal models. BAT from subject exposed daily to extremely cold outdoor temperatures has never been studied through morphological techniques. In this context, an exciting case of study are the citizens of Yakutsk, an East- ern Siberian population exposed to the annual average temperature of -10 °C, that peaks up to -50°C during winter. In autoptic fat biopsies from a 54-year-old patient living in Yakutsk BAT is present in the perirenal and para-aortic fat specimens. Importantly, the mean adipocyte area of ... : Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015 ... Article in Journal/Newspaper Yakutsk DataCite Metadata Store (German National Library of Science and Technology) Yakutsk Browning ENVELOPE(164.050,164.050,-74.617,-74.617) |
institution |
Open Polar |
collection |
DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
ftdatacite |
language |
English |
topic |
Brown adipose tissue; white adipose tissue; obesity; diabetes; low temperature |
spellingShingle |
Brown adipose tissue; white adipose tissue; obesity; diabetes; low temperature Severi, Ilenia Innokentevich, Tomskii Mikhail Gavrilievich, Tikhonov Dmitrii Savvichna, Loskutova Kiunniai Andreevich, Isakov Evgeny Giordano, Antonio Gesuita, Rosaria Cinti, Saverio The city of Yakutsk: a case of study for human brown adipose tissue in extremely cold conditions ... |
topic_facet |
Brown adipose tissue; white adipose tissue; obesity; diabetes; low temperature |
description |
The discovery of the presence of functional brown adipose tissue (BAT) also in healthy humans [1-3] has focused the attention of the scientific community on the possibility to expand body BAT content as a therapeutic strategy for the treatment and prevention of obesity and the associated metabolic disorders. Indeed, white-to- brown adipocyte transdifferentiation, leading to “browning” of the adipose organ, has been shown to reduce body weight and improve metabolic parameters in obese and insulin-resistant animal models. BAT from subject exposed daily to extremely cold outdoor temperatures has never been studied through morphological techniques. In this context, an exciting case of study are the citizens of Yakutsk, an East- ern Siberian population exposed to the annual average temperature of -10 °C, that peaks up to -50°C during winter. In autoptic fat biopsies from a 54-year-old patient living in Yakutsk BAT is present in the perirenal and para-aortic fat specimens. Importantly, the mean adipocyte area of ... : Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015 ... |
format |
Article in Journal/Newspaper |
author |
Severi, Ilenia Innokentevich, Tomskii Mikhail Gavrilievich, Tikhonov Dmitrii Savvichna, Loskutova Kiunniai Andreevich, Isakov Evgeny Giordano, Antonio Gesuita, Rosaria Cinti, Saverio |
author_facet |
Severi, Ilenia Innokentevich, Tomskii Mikhail Gavrilievich, Tikhonov Dmitrii Savvichna, Loskutova Kiunniai Andreevich, Isakov Evgeny Giordano, Antonio Gesuita, Rosaria Cinti, Saverio |
author_sort |
Severi, Ilenia |
title |
The city of Yakutsk: a case of study for human brown adipose tissue in extremely cold conditions ... |
title_short |
The city of Yakutsk: a case of study for human brown adipose tissue in extremely cold conditions ... |
title_full |
The city of Yakutsk: a case of study for human brown adipose tissue in extremely cold conditions ... |
title_fullStr |
The city of Yakutsk: a case of study for human brown adipose tissue in extremely cold conditions ... |
title_full_unstemmed |
The city of Yakutsk: a case of study for human brown adipose tissue in extremely cold conditions ... |
title_sort |
city of yakutsk: a case of study for human brown adipose tissue in extremely cold conditions ... |
publisher |
Italian Journal of Anatomy and Embryology |
publishDate |
2015 |
url |
https://dx.doi.org/10.13128/ijae-16910 http://www.fupress.net/index.php/ijae/article/view/16910/15805 |
long_lat |
ENVELOPE(164.050,164.050,-74.617,-74.617) |
geographic |
Yakutsk Browning |
geographic_facet |
Yakutsk Browning |
genre |
Yakutsk |
genre_facet |
Yakutsk |
op_relation |
https://dx.doi.org/10.13128/ijae-16910 |
op_doi |
https://doi.org/10.13128/ijae-1691010.13128/ijae-16910 |
_version_ |
1775356726575366144 |