Genomic and Virulence Profiling of Erysipelothrix rhusiopathiae Isolated from Widespread Muskox Mortalities in Arctic Archipelago ...
Muskoxen are an important food and economic resource for the indigenous people in the Canadian Arctic; however, in recent years this species has experienced substantial disease-related population declines. A single strain (‘Arctic clone’) of Erysipelothrix rhusiopathiae was associated with mass mort...
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Online Access: | https://dx.doi.org/10.11575/prism/dspace/40953 https://prism.ucalgary.ca/handle/1880/116107 |
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ftdatacite:10.11575/prism/dspace/40953 2023-11-05T03:37:56+01:00 Genomic and Virulence Profiling of Erysipelothrix rhusiopathiae Isolated from Widespread Muskox Mortalities in Arctic Archipelago ... Seru, Lakshmi Vineesha 2023 https://dx.doi.org/10.11575/prism/dspace/40953 https://prism.ucalgary.ca/handle/1880/116107 en eng Graduate Studies University of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission. Arctic muskoxen mortality Erysipelothrix rhusiopathiae virulence genes pathogenicity islands prophages pan-genome wide association studies Veterinary Science article master thesis CreativeWork Other 2023 ftdatacite https://doi.org/10.11575/prism/dspace/40953 2023-10-09T11:06:44Z Muskoxen are an important food and economic resource for the indigenous people in the Canadian Arctic; however, in recent years this species has experienced substantial disease-related population declines. A single strain (‘Arctic clone’) of Erysipelothrix rhusiopathiae was associated with mass mortalities of muskoxen on Banks and Victoria Islands in 2010-2013, and various wild species on Prince Patrick Island in 2017. In 2021, an outbreak of E. rhusiopathiae was reported for the first time in muskoxen on Ellesmere Island. The predominance of the Arctic clone in the Arctic raises the question of virulence of this lineage. Objectives of this study were to characterize E. rhusiopathiae isolates from Ellesmere Island and identify amino acid sequence variations among 17 virulence genes, pathogenicity islands and prophages among 28 Arctic clone and 31 other closely related E. rhusiopathiae genomes. In addition, unique genetic contents of the Arctic clone that may encode virulence traits were determined via ... Master Thesis Arctic Archipelago Arctic Ellesmere Island muskox Prince Patrick Island DataCite Metadata Store (German National Library of Science and Technology) |
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Open Polar |
collection |
DataCite Metadata Store (German National Library of Science and Technology) |
op_collection_id |
ftdatacite |
language |
English |
topic |
Arctic muskoxen mortality Erysipelothrix rhusiopathiae virulence genes pathogenicity islands prophages pan-genome wide association studies Veterinary Science |
spellingShingle |
Arctic muskoxen mortality Erysipelothrix rhusiopathiae virulence genes pathogenicity islands prophages pan-genome wide association studies Veterinary Science Seru, Lakshmi Vineesha Genomic and Virulence Profiling of Erysipelothrix rhusiopathiae Isolated from Widespread Muskox Mortalities in Arctic Archipelago ... |
topic_facet |
Arctic muskoxen mortality Erysipelothrix rhusiopathiae virulence genes pathogenicity islands prophages pan-genome wide association studies Veterinary Science |
description |
Muskoxen are an important food and economic resource for the indigenous people in the Canadian Arctic; however, in recent years this species has experienced substantial disease-related population declines. A single strain (‘Arctic clone’) of Erysipelothrix rhusiopathiae was associated with mass mortalities of muskoxen on Banks and Victoria Islands in 2010-2013, and various wild species on Prince Patrick Island in 2017. In 2021, an outbreak of E. rhusiopathiae was reported for the first time in muskoxen on Ellesmere Island. The predominance of the Arctic clone in the Arctic raises the question of virulence of this lineage. Objectives of this study were to characterize E. rhusiopathiae isolates from Ellesmere Island and identify amino acid sequence variations among 17 virulence genes, pathogenicity islands and prophages among 28 Arctic clone and 31 other closely related E. rhusiopathiae genomes. In addition, unique genetic contents of the Arctic clone that may encode virulence traits were determined via ... |
format |
Master Thesis |
author |
Seru, Lakshmi Vineesha |
author_facet |
Seru, Lakshmi Vineesha |
author_sort |
Seru, Lakshmi Vineesha |
title |
Genomic and Virulence Profiling of Erysipelothrix rhusiopathiae Isolated from Widespread Muskox Mortalities in Arctic Archipelago ... |
title_short |
Genomic and Virulence Profiling of Erysipelothrix rhusiopathiae Isolated from Widespread Muskox Mortalities in Arctic Archipelago ... |
title_full |
Genomic and Virulence Profiling of Erysipelothrix rhusiopathiae Isolated from Widespread Muskox Mortalities in Arctic Archipelago ... |
title_fullStr |
Genomic and Virulence Profiling of Erysipelothrix rhusiopathiae Isolated from Widespread Muskox Mortalities in Arctic Archipelago ... |
title_full_unstemmed |
Genomic and Virulence Profiling of Erysipelothrix rhusiopathiae Isolated from Widespread Muskox Mortalities in Arctic Archipelago ... |
title_sort |
genomic and virulence profiling of erysipelothrix rhusiopathiae isolated from widespread muskox mortalities in arctic archipelago ... |
publisher |
Graduate Studies |
publishDate |
2023 |
url |
https://dx.doi.org/10.11575/prism/dspace/40953 https://prism.ucalgary.ca/handle/1880/116107 |
genre |
Arctic Archipelago Arctic Ellesmere Island muskox Prince Patrick Island |
genre_facet |
Arctic Archipelago Arctic Ellesmere Island muskox Prince Patrick Island |
op_rights |
University of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission. |
op_doi |
https://doi.org/10.11575/prism/dspace/40953 |
_version_ |
1781693641498034176 |