Algesthesia after epileptic seizure
The consequences of epileptic seizures related to postictal inhibition in early postictal period include postictal analgesia. We studied this phenomenon over 96 h following flurothyl-induced seizures in adult male Wistar rats. Nociception of control (no seizure) and seizured groups were tested using...
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ftczechacademysc:oai:kramerius.lib.cas.cz:uuid:f95c8263-fdc1-4c5a-8eed-c2bc7f5426fb 2024-03-17T09:00:00+00:00 Algesthesia after epileptic seizure Mareš, Jan , 1948- Rokyta, Richard , 1938- print https://kramerius.lib.cas.cz/view/uuid:f95c8263-fdc1-4c5a-8eed-c2bc7f5426fb unknown https://kramerius.lib.cas.cz/view/uuid:f95c8263-fdc1-4c5a-8eed-c2bc7f5426fb policy:public Patologie. Klinická medicína patologie epileptické záchvaty analgezie krysa obecná pathology epileptic seizures analgesia Rattus rattus nociception flurothyl postictal analgesia 14 616 article články model:article ftczechacademysc 2024-02-19T23:19:02Z The consequences of epileptic seizures related to postictal inhibition in early postictal period include postictal analgesia. We studied this phenomenon over 96 h following flurothyl-induced seizures in adult male Wistar rats. Nociception of control (no seizure) and seizured groups were tested using the plantar and von Frey hair tests. We determined latency of forepaw and hind paw reactions using plantar tests and the number of von Frey hairs reactions. Shortly after seizures, longer plantar test latencies were seen relative to the control group. Before the seizures the plantar test reaction times were significantly shorter in forepaws than in hind paws. The effect disappeared post-seizure and surprisingly, it also disappeared at the corresponding time in controls; it reappeared after 48 h in the seizure group and after 24 h in controls. Differences in the von Frey hairs test occurred at 5 and 60 min post-seizure, however, these differences could not be explained by limb anatomy; although, different thermal and mechanical nociception mechanisms could be significant. The unexpected reactions in controls could be related to brief social and physical interactions between the two groups. J. Mareš, R. Rokyta. Article in Journal/Newspaper Rattus rattus Czech Academy of Sciences: dKNAV |
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Czech Academy of Sciences: dKNAV |
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ftczechacademysc |
language |
unknown |
topic |
Patologie. Klinická medicína patologie epileptické záchvaty analgezie krysa obecná pathology epileptic seizures analgesia Rattus rattus nociception flurothyl postictal analgesia 14 616 |
spellingShingle |
Patologie. Klinická medicína patologie epileptické záchvaty analgezie krysa obecná pathology epileptic seizures analgesia Rattus rattus nociception flurothyl postictal analgesia 14 616 Mareš, Jan , 1948- Rokyta, Richard , 1938- Algesthesia after epileptic seizure |
topic_facet |
Patologie. Klinická medicína patologie epileptické záchvaty analgezie krysa obecná pathology epileptic seizures analgesia Rattus rattus nociception flurothyl postictal analgesia 14 616 |
description |
The consequences of epileptic seizures related to postictal inhibition in early postictal period include postictal analgesia. We studied this phenomenon over 96 h following flurothyl-induced seizures in adult male Wistar rats. Nociception of control (no seizure) and seizured groups were tested using the plantar and von Frey hair tests. We determined latency of forepaw and hind paw reactions using plantar tests and the number of von Frey hairs reactions. Shortly after seizures, longer plantar test latencies were seen relative to the control group. Before the seizures the plantar test reaction times were significantly shorter in forepaws than in hind paws. The effect disappeared post-seizure and surprisingly, it also disappeared at the corresponding time in controls; it reappeared after 48 h in the seizure group and after 24 h in controls. Differences in the von Frey hairs test occurred at 5 and 60 min post-seizure, however, these differences could not be explained by limb anatomy; although, different thermal and mechanical nociception mechanisms could be significant. The unexpected reactions in controls could be related to brief social and physical interactions between the two groups. J. Mareš, R. Rokyta. |
format |
Article in Journal/Newspaper |
author |
Mareš, Jan , 1948- Rokyta, Richard , 1938- |
author_facet |
Mareš, Jan , 1948- Rokyta, Richard , 1938- |
author_sort |
Mareš, Jan , 1948- |
title |
Algesthesia after epileptic seizure |
title_short |
Algesthesia after epileptic seizure |
title_full |
Algesthesia after epileptic seizure |
title_fullStr |
Algesthesia after epileptic seizure |
title_full_unstemmed |
Algesthesia after epileptic seizure |
title_sort |
algesthesia after epileptic seizure |
url |
https://kramerius.lib.cas.cz/view/uuid:f95c8263-fdc1-4c5a-8eed-c2bc7f5426fb |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_relation |
https://kramerius.lib.cas.cz/view/uuid:f95c8263-fdc1-4c5a-8eed-c2bc7f5426fb |
op_rights |
policy:public |
_version_ |
1793771039955615744 |