Rodents as Sentinels for the Prevalence of Tick-Borne Encephalitis Virus
Tick-borne encephalitis virus (TBEV) causes one of the most important flavivirus infections of the central nervous system, affecting humans in Europe and Asia. To test the suitability of rodents as a surrogate marker for virus spread, laboratory-bred Microtus arvalis voles were experimentally infect...
Published in: | Vector-Borne and Zoonotic Diseases |
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Online Access: | https://doi.org/10.1089/vbz.2010.0236 http://hdl.handle.net/11104/0198738 |
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ftczacademyscien:oai:asep.lib.cas.cz:CavUnEpca/0361426 2024-09-15T18:18:44+00:00 Rodents as Sentinels for the Prevalence of Tick-Borne Encephalitis Virus Achazi, K. Růžek, D. (Daniel) Donoso-Mantke, O. Schlegel, M. Ali, H. S. Wenk, M. Schmidt-Chanasit, J. Ohlmeyer, L. Ruhe, F. Vor, T. Kiffner, Ch. Kallies, R. Ulrich, R. G. Niedrig, M. 2011 https://doi.org/10.1089/vbz.2010.0236 http://hdl.handle.net/11104/0198738 eng eng doi:10.1089/vbz.2010.0236 urn:pissn: 1530-3667 urn:eissn: 1557-7759 http://hdl.handle.net/11104/0198738 Distribution Monitoring Rodents Tick-borne encephalitis Zoonosis info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2011 ftczacademyscien https://doi.org/10.1089/vbz.2010.0236 2024-08-19T05:32:57Z Tick-borne encephalitis virus (TBEV) causes one of the most important flavivirus infections of the central nervous system, affecting humans in Europe and Asia. To test the suitability of rodents as a surrogate marker for virus spread, laboratory-bred Microtus arvalis voles were experimentally infected with TBEV and analyzed over a period of 100 days by real-time (RT)-quantitative PCR. Further, the prevalence of TBEV in rodents trapped in Brandenburg (Germany) was determined. In experimentally infected M. arvalis voles, TBEV was detectable in different organs for at least 3 months and in blood for 1 month. 10% of all rodents investigated were positive for TBEV. TBEV was detected in 6 rodent species: Apodemus agrarius, Apodemus flavicollis, Apodemus sylvaticus, Microtus agrestis, Microtus arvalis, and Myodes glareolus. M. glareolus showed a high infection rate in all areas investigated. These voles developed a persistent TBE infection without clinical symptoms. Article in Journal/Newspaper Microtus arvalis The Czech Academy of Sciences: Publication Activity (ASEP) Vector-Borne and Zoonotic Diseases 11 6 641 647 |
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Open Polar |
collection |
The Czech Academy of Sciences: Publication Activity (ASEP) |
op_collection_id |
ftczacademyscien |
language |
English |
topic |
Distribution Monitoring Rodents Tick-borne encephalitis Zoonosis |
spellingShingle |
Distribution Monitoring Rodents Tick-borne encephalitis Zoonosis Achazi, K. Růžek, D. (Daniel) Donoso-Mantke, O. Schlegel, M. Ali, H. S. Wenk, M. Schmidt-Chanasit, J. Ohlmeyer, L. Ruhe, F. Vor, T. Kiffner, Ch. Kallies, R. Ulrich, R. G. Niedrig, M. Rodents as Sentinels for the Prevalence of Tick-Borne Encephalitis Virus |
topic_facet |
Distribution Monitoring Rodents Tick-borne encephalitis Zoonosis |
description |
Tick-borne encephalitis virus (TBEV) causes one of the most important flavivirus infections of the central nervous system, affecting humans in Europe and Asia. To test the suitability of rodents as a surrogate marker for virus spread, laboratory-bred Microtus arvalis voles were experimentally infected with TBEV and analyzed over a period of 100 days by real-time (RT)-quantitative PCR. Further, the prevalence of TBEV in rodents trapped in Brandenburg (Germany) was determined. In experimentally infected M. arvalis voles, TBEV was detectable in different organs for at least 3 months and in blood for 1 month. 10% of all rodents investigated were positive for TBEV. TBEV was detected in 6 rodent species: Apodemus agrarius, Apodemus flavicollis, Apodemus sylvaticus, Microtus agrestis, Microtus arvalis, and Myodes glareolus. M. glareolus showed a high infection rate in all areas investigated. These voles developed a persistent TBE infection without clinical symptoms. |
format |
Article in Journal/Newspaper |
author |
Achazi, K. Růžek, D. (Daniel) Donoso-Mantke, O. Schlegel, M. Ali, H. S. Wenk, M. Schmidt-Chanasit, J. Ohlmeyer, L. Ruhe, F. Vor, T. Kiffner, Ch. Kallies, R. Ulrich, R. G. Niedrig, M. |
author_facet |
Achazi, K. Růžek, D. (Daniel) Donoso-Mantke, O. Schlegel, M. Ali, H. S. Wenk, M. Schmidt-Chanasit, J. Ohlmeyer, L. Ruhe, F. Vor, T. Kiffner, Ch. Kallies, R. Ulrich, R. G. Niedrig, M. |
author_sort |
Achazi, K. |
title |
Rodents as Sentinels for the Prevalence of Tick-Borne Encephalitis Virus |
title_short |
Rodents as Sentinels for the Prevalence of Tick-Borne Encephalitis Virus |
title_full |
Rodents as Sentinels for the Prevalence of Tick-Borne Encephalitis Virus |
title_fullStr |
Rodents as Sentinels for the Prevalence of Tick-Borne Encephalitis Virus |
title_full_unstemmed |
Rodents as Sentinels for the Prevalence of Tick-Borne Encephalitis Virus |
title_sort |
rodents as sentinels for the prevalence of tick-borne encephalitis virus |
publishDate |
2011 |
url |
https://doi.org/10.1089/vbz.2010.0236 http://hdl.handle.net/11104/0198738 |
genre |
Microtus arvalis |
genre_facet |
Microtus arvalis |
op_relation |
doi:10.1089/vbz.2010.0236 urn:pissn: 1530-3667 urn:eissn: 1557-7759 http://hdl.handle.net/11104/0198738 |
op_doi |
https://doi.org/10.1089/vbz.2010.0236 |
container_title |
Vector-Borne and Zoonotic Diseases |
container_volume |
11 |
container_issue |
6 |
container_start_page |
641 |
op_container_end_page |
647 |
_version_ |
1810456816572694528 |