Immune response of turbot, Psetta maxima (L.) (Pisces: Teleostei), to formalin-killed scuticociliates (Ciliophora) and adjuvanted formulations
The increasing frequency of scuticociliatosis in turbot culture has stressed the need of knowledge on the immune responses to these parasites, for further developing of prevention and control strategies. The immune response of turbot to killed parasites, alone (Ag) or in combination with Montanide I...
Published in: | Fish & Shellfish Immunology |
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Language: | English |
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Academic Press
2008
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Online Access: | http://hdl.handle.net/10261/71992 https://doi.org/10.1016/j.fsi.2007.06.007 |
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ftcsic:oai:digital.csic.es:10261/71992 2024-02-11T10:09:16+01:00 Immune response of turbot, Psetta maxima (L.) (Pisces: Teleostei), to formalin-killed scuticociliates (Ciliophora) and adjuvanted formulations Sitjà-Bobadilla, Ariadna Palenzuela, Oswaldo Álvarez-Pellitero, Mª del Pilar 2008 http://hdl.handle.net/10261/71992 https://doi.org/10.1016/j.fsi.2007.06.007 en eng Academic Press doi:10.1016/j.fsi.2007.06.007 issn: 1050-4648 Fish and Shellfish Immunology 24(1): 1-10 (2008) http://hdl.handle.net/10261/71992 none artículo http://purl.org/coar/resource_type/c_6501 2008 ftcsic https://doi.org/10.1016/j.fsi.2007.06.007 2024-01-16T09:47:31Z The increasing frequency of scuticociliatosis in turbot culture has stressed the need of knowledge on the immune responses to these parasites, for further developing of prevention and control strategies. The immune response of turbot to killed parasites, alone (Ag) or in combination with Montanide ISA 763A (MON), was studied in a laboratory-scale experiment. The variations of several innate immune factors and the antibody response were analysed in immunized vs. non-immunized fish at different times after immunization, and also after a challenge with live ciliates. Amongst innate immune factors, serum lysozyme increased progressively in all inoculated groups. Differences in innate immune factors in Ag and Ag-MON fish with respect to controls were mainly evidenced after challenge, especially for serum complement. Serum antibody levels increased in immunized fish after booster and particularly after challenge. In addition, certain protection was obtained for immunized groups compared to controls or to fish receiving MON alone, and the levels of specific antibodies were also the highest in immunized groups. The obtained information could be useful for further design of immunoprophylactic formulations against scuticociliatosis. © 2007 Elsevier Ltd. All rights reserved. Peer Reviewed Article in Journal/Newspaper Turbot Digital.CSIC (Spanish National Research Council) Fish & Shellfish Immunology 24 1 1 10 |
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Digital.CSIC (Spanish National Research Council) |
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ftcsic |
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English |
description |
The increasing frequency of scuticociliatosis in turbot culture has stressed the need of knowledge on the immune responses to these parasites, for further developing of prevention and control strategies. The immune response of turbot to killed parasites, alone (Ag) or in combination with Montanide ISA 763A (MON), was studied in a laboratory-scale experiment. The variations of several innate immune factors and the antibody response were analysed in immunized vs. non-immunized fish at different times after immunization, and also after a challenge with live ciliates. Amongst innate immune factors, serum lysozyme increased progressively in all inoculated groups. Differences in innate immune factors in Ag and Ag-MON fish with respect to controls were mainly evidenced after challenge, especially for serum complement. Serum antibody levels increased in immunized fish after booster and particularly after challenge. In addition, certain protection was obtained for immunized groups compared to controls or to fish receiving MON alone, and the levels of specific antibodies were also the highest in immunized groups. The obtained information could be useful for further design of immunoprophylactic formulations against scuticociliatosis. © 2007 Elsevier Ltd. All rights reserved. Peer Reviewed |
format |
Article in Journal/Newspaper |
author |
Sitjà-Bobadilla, Ariadna Palenzuela, Oswaldo Álvarez-Pellitero, Mª del Pilar |
spellingShingle |
Sitjà-Bobadilla, Ariadna Palenzuela, Oswaldo Álvarez-Pellitero, Mª del Pilar Immune response of turbot, Psetta maxima (L.) (Pisces: Teleostei), to formalin-killed scuticociliates (Ciliophora) and adjuvanted formulations |
author_facet |
Sitjà-Bobadilla, Ariadna Palenzuela, Oswaldo Álvarez-Pellitero, Mª del Pilar |
author_sort |
Sitjà-Bobadilla, Ariadna |
title |
Immune response of turbot, Psetta maxima (L.) (Pisces: Teleostei), to formalin-killed scuticociliates (Ciliophora) and adjuvanted formulations |
title_short |
Immune response of turbot, Psetta maxima (L.) (Pisces: Teleostei), to formalin-killed scuticociliates (Ciliophora) and adjuvanted formulations |
title_full |
Immune response of turbot, Psetta maxima (L.) (Pisces: Teleostei), to formalin-killed scuticociliates (Ciliophora) and adjuvanted formulations |
title_fullStr |
Immune response of turbot, Psetta maxima (L.) (Pisces: Teleostei), to formalin-killed scuticociliates (Ciliophora) and adjuvanted formulations |
title_full_unstemmed |
Immune response of turbot, Psetta maxima (L.) (Pisces: Teleostei), to formalin-killed scuticociliates (Ciliophora) and adjuvanted formulations |
title_sort |
immune response of turbot, psetta maxima (l.) (pisces: teleostei), to formalin-killed scuticociliates (ciliophora) and adjuvanted formulations |
publisher |
Academic Press |
publishDate |
2008 |
url |
http://hdl.handle.net/10261/71992 https://doi.org/10.1016/j.fsi.2007.06.007 |
genre |
Turbot |
genre_facet |
Turbot |
op_relation |
doi:10.1016/j.fsi.2007.06.007 issn: 1050-4648 Fish and Shellfish Immunology 24(1): 1-10 (2008) http://hdl.handle.net/10261/71992 |
op_rights |
none |
op_doi |
https://doi.org/10.1016/j.fsi.2007.06.007 |
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Fish & Shellfish Immunology |
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24 |
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1 |
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1 |
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10 |
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1790609076260962304 |