DNA methylation landscapes before and after Pacific Oyster Mortality Syndrome are different within and between resistant and susceptible Magallana gigas

• Published in: Science of The Total Environment
• Main Authors: Valdivieso, Alejandro, Morga, Benjamin, Degremont, Lionel, Mege, Mickaël, Courtay, Gaëlle, Dorant, Yann, Escoubas, Jean-Michel, Gawra, Janan, de Lorgeril, Julien, Mitta, Guillaume, Cosseau, Celine, Vidal-Dupiol, Jeremie
• Format: Article in Journal/Newspaper
• Language: English
• Published: Elsevier 2025
• Subjects: POMS; DNA methylation; Epibiomarkers; Immune response; OsHV-1 μVar; Oyster; Ensure healthy lives and promote well-being for all at all ages; Ensure availability and sustainable management of water and sanitation for all; Build resilient infrastructure; promote inclusive and sustainable industrialization and foster innovation; Pacific; Guillaume; Pacific oyster
• Online Access: http://hdl.handle.net/10261/376905; https://doi.org/10.1016/j.scitotenv.2025.178385; https://api.elsevier.com/content/abstract/scopus_id/85214530260

Pacific oysters face recurring outbreaks of Pacific Oyster Mortality Syndrome (POMS), a polymicrobial multifactorial disease. Although this interaction is increasingly understood, the role of epigenetics (e.g., DNA methylation) appears to be of fundamental importance because of its ability to shape...