Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus) A comparison between bacterium, parasite and virus diseases
One of the main objectives of genetic breeding programs in turbot industry is to reduce disease-related mortality. In the present study, a genome scan to detect quantitative trait loci (QTL) affecting resistance and survival to viral haemorrhagic septicaemia (VHS) was carried out. Three full-sib fam...
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ftcsic:oai:digital.csic.es:10261/293242 2024-02-11T10:08:27+01:00 Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus) A comparison between bacterium, parasite and virus diseases Rodríguez-Ramilo, S. T. De La Herrán, R. Ruiz-Rejón, C. Hermida, M. Fernández, C. Pereiro, P. Figueras, A. Bouza, C. Toro, M. A. Martínez, P. Fernández, J. 2014 https://hdl.handle.net/20.500.12792/3846 http://hdl.handle.net/10261/293242 https://doi.org/10.1007/s10126-013-9544-x en eng Springer Marine Biotechnology 16: 265-276 (2014) 1436-2228 http://hdl.handle.net/20.500.12792/3846 http://hdl.handle.net/10261/293242 doi:10.1007/s10126-013-9544-x 1436-2236 none QTL Turbot Viral haemorrhagic septicaemia Linear regression Maximum likelihood journal article 2014 ftcsic https://doi.org/20.500.12792/384610.1007/s10126-013-9544-x 2024-01-16T11:36:37Z One of the main objectives of genetic breeding programs in turbot industry is to reduce disease-related mortality. In the present study, a genome scan to detect quantitative trait loci (QTL) affecting resistance and survival to viral haemorrhagic septicaemia (VHS) was carried out. Three full-sib families with approximately 90 individuals each were genotyped and evaluated by linear regression and maximum likelihood approaches. In addition, a comparison between QTL detected for resistance and survival time to other important bacterial and parasite diseases affecting turbot (furunculosis and scuticociliatosis) was also carried out. Finally, the relationship between QTL affecting resistance/survival time to the virus and growth-related QTL was also evaluated. Several genomic regions controlling resistance and survival time to VHS were detected. Also significant associations between the evaluated traits and genotypes at particular markers were identified, explaining up to 14 % of the phenotypic variance. Several genomic regions controlling general and specific resistance to different diseases in turbot were detected. A preliminary gene mining approach identified candidate genes related to general or specific immunity. This information will be valuable to develop marker-assisted selection programs and to discover candidate genes related to disease resistance to improve turbot production. © 2013 Springer Science+Business Media New York. Article in Journal/Newspaper Scophthalmus maximus Turbot Digital.CSIC (Spanish National Research Council) Marine Biotechnology 16 3 265 276 |
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Open Polar |
collection |
Digital.CSIC (Spanish National Research Council) |
op_collection_id |
ftcsic |
language |
English |
topic |
QTL Turbot Viral haemorrhagic septicaemia Linear regression Maximum likelihood |
spellingShingle |
QTL Turbot Viral haemorrhagic septicaemia Linear regression Maximum likelihood Rodríguez-Ramilo, S. T. De La Herrán, R. Ruiz-Rejón, C. Hermida, M. Fernández, C. Pereiro, P. Figueras, A. Bouza, C. Toro, M. A. Martínez, P. Fernández, J. Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus) A comparison between bacterium, parasite and virus diseases |
topic_facet |
QTL Turbot Viral haemorrhagic septicaemia Linear regression Maximum likelihood |
description |
One of the main objectives of genetic breeding programs in turbot industry is to reduce disease-related mortality. In the present study, a genome scan to detect quantitative trait loci (QTL) affecting resistance and survival to viral haemorrhagic septicaemia (VHS) was carried out. Three full-sib families with approximately 90 individuals each were genotyped and evaluated by linear regression and maximum likelihood approaches. In addition, a comparison between QTL detected for resistance and survival time to other important bacterial and parasite diseases affecting turbot (furunculosis and scuticociliatosis) was also carried out. Finally, the relationship between QTL affecting resistance/survival time to the virus and growth-related QTL was also evaluated. Several genomic regions controlling resistance and survival time to VHS were detected. Also significant associations between the evaluated traits and genotypes at particular markers were identified, explaining up to 14 % of the phenotypic variance. Several genomic regions controlling general and specific resistance to different diseases in turbot were detected. A preliminary gene mining approach identified candidate genes related to general or specific immunity. This information will be valuable to develop marker-assisted selection programs and to discover candidate genes related to disease resistance to improve turbot production. © 2013 Springer Science+Business Media New York. |
format |
Article in Journal/Newspaper |
author |
Rodríguez-Ramilo, S. T. De La Herrán, R. Ruiz-Rejón, C. Hermida, M. Fernández, C. Pereiro, P. Figueras, A. Bouza, C. Toro, M. A. Martínez, P. Fernández, J. |
author_facet |
Rodríguez-Ramilo, S. T. De La Herrán, R. Ruiz-Rejón, C. Hermida, M. Fernández, C. Pereiro, P. Figueras, A. Bouza, C. Toro, M. A. Martínez, P. Fernández, J. |
author_sort |
Rodríguez-Ramilo, S. T. |
title |
Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus) A comparison between bacterium, parasite and virus diseases |
title_short |
Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus) A comparison between bacterium, parasite and virus diseases |
title_full |
Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus) A comparison between bacterium, parasite and virus diseases |
title_fullStr |
Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus) A comparison between bacterium, parasite and virus diseases |
title_full_unstemmed |
Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus) A comparison between bacterium, parasite and virus diseases |
title_sort |
identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (vhs) in turbot (scophthalmus maximus) a comparison between bacterium, parasite and virus diseases |
publisher |
Springer |
publishDate |
2014 |
url |
https://hdl.handle.net/20.500.12792/3846 http://hdl.handle.net/10261/293242 https://doi.org/10.1007/s10126-013-9544-x |
genre |
Scophthalmus maximus Turbot |
genre_facet |
Scophthalmus maximus Turbot |
op_relation |
Marine Biotechnology 16: 265-276 (2014) 1436-2228 http://hdl.handle.net/20.500.12792/3846 http://hdl.handle.net/10261/293242 doi:10.1007/s10126-013-9544-x 1436-2236 |
op_rights |
none |
op_doi |
https://doi.org/20.500.12792/384610.1007/s10126-013-9544-x |
container_title |
Marine Biotechnology |
container_volume |
16 |
container_issue |
3 |
container_start_page |
265 |
op_container_end_page |
276 |
_version_ |
1790607789620461568 |