Identification of the major sex-determining region of turbot (Scophthalmus maximus)
Sex determination in fish is a labile character in evolutionary terms. The sex-determining (SD) master gene can differ even between closely related fish species. This group is an interesting model for studying the evolution of the SD region and the gonadal differentiation pathway. The turbot (Scopht...
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Language: | English |
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Oxford University Press
2009
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Online Access: | https://hdl.handle.net/20.500.12792/2722 http://hdl.handle.net/10261/292081 https://doi.org/10.1534/genetics.109.107979 |
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ftcsic:oai:digital.csic.es:10261/292081 2024-02-11T10:08:26+01:00 Identification of the major sex-determining region of turbot (Scophthalmus maximus) Martínez, P. Bouza, C. Hermida, M. Fernández, J. Toro, M. A. Vera, M. Pardo, B. Millán, A. Fernández, C. Vilas, R. Viñas, A. Sánchez, L. Felip, A. Piferrer, F. Ferreiro, I. Cabaleiro, S. 2009 https://hdl.handle.net/20.500.12792/2722 http://hdl.handle.net/10261/292081 https://doi.org/10.1534/genetics.109.107979 en eng Oxford University Press Genetics 183: 1443-1452 (2009) 0016-6731 http://hdl.handle.net/20.500.12792/2722 http://hdl.handle.net/10261/292081 doi:10.1534/genetics.109.107979 1943-2631 none artículo 2009 ftcsic https://doi.org/20.500.12792/272210.1534/genetics.109.107979 2024-01-16T11:35:56Z Sex determination in fish is a labile character in evolutionary terms. The sex-determining (SD) master gene can differ even between closely related fish species. This group is an interesting model for studying the evolution of the SD region and the gonadal differentiation pathway. The turbot (Scophthalmus maximus) is a flatfish of great commercial value, where a strong sexual dimorphism exists for growth rate. Following a QTL and marker association approach in five families and a natural population, we identified the main SD region of turbot at the proximal end of linkage group (LG) 5, close to the SmaUSC-E30 marker. The refined map of this region suggested that this marker would be 2.6 cM and 1.4 Mb from the putative SD gene. This region appeared mostly undifferentiated between males and females, and no relevant recombination frequency differences were detected between sexes. Comparative genomics of LG5 marker sequences against five model species showed no similarity of this chromosome to the sex chromosomes of medaka, stickleback, and fugu, but suggested a similarity to a sex-associated QTL from Oreochromis spp. The segregation analysis of the closest markers to the SD region demonstrated a ZW/ZZ model of sex determination in turbot. A small proportion of families did not fit perfectly with this model, which suggests that other minor genetic and/or environmental factors are involved in sex determination in this species. Copyright © 2009 by the Genetics Society of America. Article in Journal/Newspaper Scophthalmus maximus Turbot Digital.CSIC (Spanish National Research Council) Genetics 183 4 1443 1452 |
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Open Polar |
collection |
Digital.CSIC (Spanish National Research Council) |
op_collection_id |
ftcsic |
language |
English |
description |
Sex determination in fish is a labile character in evolutionary terms. The sex-determining (SD) master gene can differ even between closely related fish species. This group is an interesting model for studying the evolution of the SD region and the gonadal differentiation pathway. The turbot (Scophthalmus maximus) is a flatfish of great commercial value, where a strong sexual dimorphism exists for growth rate. Following a QTL and marker association approach in five families and a natural population, we identified the main SD region of turbot at the proximal end of linkage group (LG) 5, close to the SmaUSC-E30 marker. The refined map of this region suggested that this marker would be 2.6 cM and 1.4 Mb from the putative SD gene. This region appeared mostly undifferentiated between males and females, and no relevant recombination frequency differences were detected between sexes. Comparative genomics of LG5 marker sequences against five model species showed no similarity of this chromosome to the sex chromosomes of medaka, stickleback, and fugu, but suggested a similarity to a sex-associated QTL from Oreochromis spp. The segregation analysis of the closest markers to the SD region demonstrated a ZW/ZZ model of sex determination in turbot. A small proportion of families did not fit perfectly with this model, which suggests that other minor genetic and/or environmental factors are involved in sex determination in this species. Copyright © 2009 by the Genetics Society of America. |
format |
Article in Journal/Newspaper |
author |
Martínez, P. Bouza, C. Hermida, M. Fernández, J. Toro, M. A. Vera, M. Pardo, B. Millán, A. Fernández, C. Vilas, R. Viñas, A. Sánchez, L. Felip, A. Piferrer, F. Ferreiro, I. Cabaleiro, S. |
spellingShingle |
Martínez, P. Bouza, C. Hermida, M. Fernández, J. Toro, M. A. Vera, M. Pardo, B. Millán, A. Fernández, C. Vilas, R. Viñas, A. Sánchez, L. Felip, A. Piferrer, F. Ferreiro, I. Cabaleiro, S. Identification of the major sex-determining region of turbot (Scophthalmus maximus) |
author_facet |
Martínez, P. Bouza, C. Hermida, M. Fernández, J. Toro, M. A. Vera, M. Pardo, B. Millán, A. Fernández, C. Vilas, R. Viñas, A. Sánchez, L. Felip, A. Piferrer, F. Ferreiro, I. Cabaleiro, S. |
author_sort |
Martínez, P. |
title |
Identification of the major sex-determining region of turbot (Scophthalmus maximus) |
title_short |
Identification of the major sex-determining region of turbot (Scophthalmus maximus) |
title_full |
Identification of the major sex-determining region of turbot (Scophthalmus maximus) |
title_fullStr |
Identification of the major sex-determining region of turbot (Scophthalmus maximus) |
title_full_unstemmed |
Identification of the major sex-determining region of turbot (Scophthalmus maximus) |
title_sort |
identification of the major sex-determining region of turbot (scophthalmus maximus) |
publisher |
Oxford University Press |
publishDate |
2009 |
url |
https://hdl.handle.net/20.500.12792/2722 http://hdl.handle.net/10261/292081 https://doi.org/10.1534/genetics.109.107979 |
genre |
Scophthalmus maximus Turbot |
genre_facet |
Scophthalmus maximus Turbot |
op_relation |
Genetics 183: 1443-1452 (2009) 0016-6731 http://hdl.handle.net/20.500.12792/2722 http://hdl.handle.net/10261/292081 doi:10.1534/genetics.109.107979 1943-2631 |
op_rights |
none |
op_doi |
https://doi.org/20.500.12792/272210.1534/genetics.109.107979 |
container_title |
Genetics |
container_volume |
183 |
container_issue |
4 |
container_start_page |
1443 |
op_container_end_page |
1452 |
_version_ |
1790607759653208064 |