Possible interaction between a rodenticide treatment and a pathogen in common vole (Microtus arvalis) during a population peak
A common vole (Microtus arvalis) population peak in Northern Spain in 2007 was treated with large scale application of chlorophacinone, an anticoagulant rodenticide of the indandione family. Voles found dead and trapped alive were collected in treated and untreated areas. Residues of chlorophacinone...
Published in: | Science of The Total Environment |
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Format: | Article in Journal/Newspaper |
Language: | English |
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Elsevier
2009
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Online Access: | http://hdl.handle.net/10261/283488 https://doi.org/10.1016/j.scitotenv.2009.10.001 https://doi.org/10.13039/501100014180 |
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ftcsic:oai:digital.csic.es:10261/283488 2024-02-11T10:02:58+01:00 Possible interaction between a rodenticide treatment and a pathogen in common vole (Microtus arvalis) during a population peak Vidal, Dolors Alzaga, Vanesa Luque-Larena, Juan José Mateo, Rafael Arroyo, Leticia Viñuela, Javier Junta de Castilla y León 2009 application/pdf http://hdl.handle.net/10261/283488 https://doi.org/10.1016/j.scitotenv.2009.10.001 https://doi.org/10.13039/501100014180 en eng Elsevier https://doi.org/10.1016/j.scitotenv.2009.10.001 Sí Science of The Total Environment 408(2): 267-271 (2009) 0048-9697 http://hdl.handle.net/10261/283488 doi:10.1016/j.scitotenv.2009.10.001 http://dx.doi.org/10.13039/501100014180 19863999 none artículo 2009 ftcsic https://doi.org/10.1016/j.scitotenv.2009.10.00110.13039/501100014180 2024-01-16T11:31:15Z A common vole (Microtus arvalis) population peak in Northern Spain in 2007 was treated with large scale application of chlorophacinone, an anticoagulant rodenticide of the indandione family. Voles found dead and trapped alive were collected in treated and untreated areas. Residues of chlorophacinone were analyzed in liver of voles by HPLC–UV. Also, the presence of the pathogen Francisella tularensis was analyzed by PCR in samples of vole spleen. Chlorophacinone (82–3800 ng/g; wet weight liver) was only detected in voles found dead in treated areas (55.5%). The prevalence of F. tularensis in voles found dead in treated areas was also particularly high (66.7%). Moreover, chlorophacinone levels were lower in voles that were PCR-positive for F. tularensis (geometric mean [95% CI], 418 [143–1219] ng/g) than in those that were PCR-negative (1084 [581–2121] ng/g). Interactions between pathogens and rodenticides might be considered to reduce the doses used in baits or to avoid the use of the more toxic 2nd generation anticoagulant rodenticides. Partial financial support was provided by the Junta de Castilla y León. Peer reviewed Article in Journal/Newspaper Common vole Microtus arvalis Digital.CSIC (Spanish National Research Council) Science of The Total Environment 408 2 267 271 |
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Open Polar |
collection |
Digital.CSIC (Spanish National Research Council) |
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ftcsic |
language |
English |
description |
A common vole (Microtus arvalis) population peak in Northern Spain in 2007 was treated with large scale application of chlorophacinone, an anticoagulant rodenticide of the indandione family. Voles found dead and trapped alive were collected in treated and untreated areas. Residues of chlorophacinone were analyzed in liver of voles by HPLC–UV. Also, the presence of the pathogen Francisella tularensis was analyzed by PCR in samples of vole spleen. Chlorophacinone (82–3800 ng/g; wet weight liver) was only detected in voles found dead in treated areas (55.5%). The prevalence of F. tularensis in voles found dead in treated areas was also particularly high (66.7%). Moreover, chlorophacinone levels were lower in voles that were PCR-positive for F. tularensis (geometric mean [95% CI], 418 [143–1219] ng/g) than in those that were PCR-negative (1084 [581–2121] ng/g). Interactions between pathogens and rodenticides might be considered to reduce the doses used in baits or to avoid the use of the more toxic 2nd generation anticoagulant rodenticides. Partial financial support was provided by the Junta de Castilla y León. Peer reviewed |
author2 |
Junta de Castilla y León |
format |
Article in Journal/Newspaper |
author |
Vidal, Dolors Alzaga, Vanesa Luque-Larena, Juan José Mateo, Rafael Arroyo, Leticia Viñuela, Javier |
spellingShingle |
Vidal, Dolors Alzaga, Vanesa Luque-Larena, Juan José Mateo, Rafael Arroyo, Leticia Viñuela, Javier Possible interaction between a rodenticide treatment and a pathogen in common vole (Microtus arvalis) during a population peak |
author_facet |
Vidal, Dolors Alzaga, Vanesa Luque-Larena, Juan José Mateo, Rafael Arroyo, Leticia Viñuela, Javier |
author_sort |
Vidal, Dolors |
title |
Possible interaction between a rodenticide treatment and a pathogen in common vole (Microtus arvalis) during a population peak |
title_short |
Possible interaction between a rodenticide treatment and a pathogen in common vole (Microtus arvalis) during a population peak |
title_full |
Possible interaction between a rodenticide treatment and a pathogen in common vole (Microtus arvalis) during a population peak |
title_fullStr |
Possible interaction between a rodenticide treatment and a pathogen in common vole (Microtus arvalis) during a population peak |
title_full_unstemmed |
Possible interaction between a rodenticide treatment and a pathogen in common vole (Microtus arvalis) during a population peak |
title_sort |
possible interaction between a rodenticide treatment and a pathogen in common vole (microtus arvalis) during a population peak |
publisher |
Elsevier |
publishDate |
2009 |
url |
http://hdl.handle.net/10261/283488 https://doi.org/10.1016/j.scitotenv.2009.10.001 https://doi.org/10.13039/501100014180 |
genre |
Common vole Microtus arvalis |
genre_facet |
Common vole Microtus arvalis |
op_relation |
https://doi.org/10.1016/j.scitotenv.2009.10.001 Sí Science of The Total Environment 408(2): 267-271 (2009) 0048-9697 http://hdl.handle.net/10261/283488 doi:10.1016/j.scitotenv.2009.10.001 http://dx.doi.org/10.13039/501100014180 19863999 |
op_rights |
none |
op_doi |
https://doi.org/10.1016/j.scitotenv.2009.10.00110.13039/501100014180 |
container_title |
Science of The Total Environment |
container_volume |
408 |
container_issue |
2 |
container_start_page |
267 |
op_container_end_page |
271 |
_version_ |
1790599071295078400 |