Canine distemper virus in wildlife in south-western Europe
Multi-host pathogens emerging and re-emerging at the wildlife–domestic animal interface affect wildlife management and conservation. This is the case of canine distemper virus (CDV), a paramyxovirus closely related to human measles virus and rinderpest virus of cattle. With an area of 10,603 km2, As...
Published in: | Transboundary and Emerging Diseases |
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Online Access: | http://hdl.handle.net/10261/278796 https://doi.org/10.1111/tbed.14323 https://doi.org/10.13039/501100011033 https://doi.org/10.13039/501100002322 https://doi.org/10.13039/501100000780 |
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ftcsic:oai:digital.csic.es:10261/278796 2024-02-11T10:02:49+01:00 Canine distemper virus in wildlife in south-western Europe Oleaga, Álvaro Blanco Vázquez, Cristina Royo, Luis J. Barral, Thiago Doria Bonnaire, Debby Armenteros, José A. Rabanal, Benjamín Gortázar, Christian Balseiro, Ana Ministerio de Ciencia, Innovación y Universidades (España) Agencia Estatal de Investigación (España) European Commission CSIC - Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brasil) 2022 http://hdl.handle.net/10261/278796 https://doi.org/10.1111/tbed.14323 https://doi.org/10.13039/501100011033 https://doi.org/10.13039/501100002322 https://doi.org/10.13039/501100000780 en eng Wiley-VCH #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-096010-B-C21/ES/EL TEJON (MELES MELES) Y LA TUBERCULOSIS ANIMAL EN ESPAÑA: INTERACCION TEJON-BOVINO EN HOTSPOT AREAS Y MEDIDAS DE CONTROL DE LA ENFERMEDAD EN LA INTERFASE/ Publisher's version https://doi.org/10.1111/tbed.14323 Sí Transboundary and Emerging Diseases 69(4): e473-e485 (2022) http://hdl.handle.net/10261/278796 doi:10.1111/tbed.14323 1865-1674 http://dx.doi.org/10.13039/501100011033 http://dx.doi.org/10.13039/501100002322 http://dx.doi.org/10.13039/501100000780 open Canine distemper virus (CDV) Epidemiology Pathology Serology South-western Europe Wildlife artículo 2022 ftcsic https://doi.org/10.1111/tbed.1432310.13039/50110001103310.13039/50110000232210.13039/501100000780 2024-01-16T11:28:43Z Multi-host pathogens emerging and re-emerging at the wildlife–domestic animal interface affect wildlife management and conservation. This is the case of canine distemper virus (CDV), a paramyxovirus closely related to human measles virus and rinderpest virus of cattle. With an area of 10,603 km2, Asturias region in Atlantic Spain is a hotspot of carnivore diversity, which includes the largest Eurasian brown bear (Ursus arctos arctos) population and one of the largest wolf (Canis lupus) populations in south-western Europe. In 2020–2021, we recorded mortality due to distemper in four carnivore species including three mustelids (Eurasian badger Meles meles, European marten Martes martes and European polecat Mustela putorius) and one canid (red fox, Vulpes vulpes). Clinical signs and pathology were similar across species and consistent with the emergence of a highly pathogenic viral strain, with CDV antigen mainly located in the central nervous system, lungs, spleen and lymph nodes. A molecular study in eight wild carnivore species, also including the Iberian wolf, Eurasian brown bear, American mink (Neovison vison) and stone marten (Martes foina), revealed 19.51% (16/82) of positivity. Phylogenetic analysis demonstrated that CDV belonged to the previously described European lineage. A retrospective serosurvey (2008–2020) showed a high seroprevalence of CDV antibodies (43.4%) in 684 analyzed badgers, indicating a long-term though not stable viral circulation in this multi-host community. The possible triggers of the 2020–2021 outbreak and the implications for carnivore management and conservation are discussed. This work has been funded by the Spanish Ministerio de Ciencia, Innovación y Universidades (MCIU) and the Agencia Estatal de Investigación (AEI) reference project RTI2018-096010-B-C21 (FEDER co-funded) and, by PCTI 2018−2020 (GRUPIN: IDI2018-000237) and FEDER. C.B.V. was supported by a grant from the Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Spain. T.D.B. was supported ... Article in Journal/Newspaper Canis lupus Ursus arctos Digital.CSIC (Spanish National Research Council) Transboundary and Emerging Diseases 69 4 |
institution |
Open Polar |
collection |
Digital.CSIC (Spanish National Research Council) |
op_collection_id |
ftcsic |
language |
English |
topic |
Canine distemper virus (CDV) Epidemiology Pathology Serology South-western Europe Wildlife |
spellingShingle |
Canine distemper virus (CDV) Epidemiology Pathology Serology South-western Europe Wildlife Oleaga, Álvaro Blanco Vázquez, Cristina Royo, Luis J. Barral, Thiago Doria Bonnaire, Debby Armenteros, José A. Rabanal, Benjamín Gortázar, Christian Balseiro, Ana Canine distemper virus in wildlife in south-western Europe |
topic_facet |
Canine distemper virus (CDV) Epidemiology Pathology Serology South-western Europe Wildlife |
description |
Multi-host pathogens emerging and re-emerging at the wildlife–domestic animal interface affect wildlife management and conservation. This is the case of canine distemper virus (CDV), a paramyxovirus closely related to human measles virus and rinderpest virus of cattle. With an area of 10,603 km2, Asturias region in Atlantic Spain is a hotspot of carnivore diversity, which includes the largest Eurasian brown bear (Ursus arctos arctos) population and one of the largest wolf (Canis lupus) populations in south-western Europe. In 2020–2021, we recorded mortality due to distemper in four carnivore species including three mustelids (Eurasian badger Meles meles, European marten Martes martes and European polecat Mustela putorius) and one canid (red fox, Vulpes vulpes). Clinical signs and pathology were similar across species and consistent with the emergence of a highly pathogenic viral strain, with CDV antigen mainly located in the central nervous system, lungs, spleen and lymph nodes. A molecular study in eight wild carnivore species, also including the Iberian wolf, Eurasian brown bear, American mink (Neovison vison) and stone marten (Martes foina), revealed 19.51% (16/82) of positivity. Phylogenetic analysis demonstrated that CDV belonged to the previously described European lineage. A retrospective serosurvey (2008–2020) showed a high seroprevalence of CDV antibodies (43.4%) in 684 analyzed badgers, indicating a long-term though not stable viral circulation in this multi-host community. The possible triggers of the 2020–2021 outbreak and the implications for carnivore management and conservation are discussed. This work has been funded by the Spanish Ministerio de Ciencia, Innovación y Universidades (MCIU) and the Agencia Estatal de Investigación (AEI) reference project RTI2018-096010-B-C21 (FEDER co-funded) and, by PCTI 2018−2020 (GRUPIN: IDI2018-000237) and FEDER. C.B.V. was supported by a grant from the Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Spain. T.D.B. was supported ... |
author2 |
Ministerio de Ciencia, Innovación y Universidades (España) Agencia Estatal de Investigación (España) European Commission CSIC - Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brasil) |
format |
Article in Journal/Newspaper |
author |
Oleaga, Álvaro Blanco Vázquez, Cristina Royo, Luis J. Barral, Thiago Doria Bonnaire, Debby Armenteros, José A. Rabanal, Benjamín Gortázar, Christian Balseiro, Ana |
author_facet |
Oleaga, Álvaro Blanco Vázquez, Cristina Royo, Luis J. Barral, Thiago Doria Bonnaire, Debby Armenteros, José A. Rabanal, Benjamín Gortázar, Christian Balseiro, Ana |
author_sort |
Oleaga, Álvaro |
title |
Canine distemper virus in wildlife in south-western Europe |
title_short |
Canine distemper virus in wildlife in south-western Europe |
title_full |
Canine distemper virus in wildlife in south-western Europe |
title_fullStr |
Canine distemper virus in wildlife in south-western Europe |
title_full_unstemmed |
Canine distemper virus in wildlife in south-western Europe |
title_sort |
canine distemper virus in wildlife in south-western europe |
publisher |
Wiley-VCH |
publishDate |
2022 |
url |
http://hdl.handle.net/10261/278796 https://doi.org/10.1111/tbed.14323 https://doi.org/10.13039/501100011033 https://doi.org/10.13039/501100002322 https://doi.org/10.13039/501100000780 |
genre |
Canis lupus Ursus arctos |
genre_facet |
Canis lupus Ursus arctos |
op_relation |
#PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-096010-B-C21/ES/EL TEJON (MELES MELES) Y LA TUBERCULOSIS ANIMAL EN ESPAÑA: INTERACCION TEJON-BOVINO EN HOTSPOT AREAS Y MEDIDAS DE CONTROL DE LA ENFERMEDAD EN LA INTERFASE/ Publisher's version https://doi.org/10.1111/tbed.14323 Sí Transboundary and Emerging Diseases 69(4): e473-e485 (2022) http://hdl.handle.net/10261/278796 doi:10.1111/tbed.14323 1865-1674 http://dx.doi.org/10.13039/501100011033 http://dx.doi.org/10.13039/501100002322 http://dx.doi.org/10.13039/501100000780 |
op_rights |
open |
op_doi |
https://doi.org/10.1111/tbed.1432310.13039/50110001103310.13039/50110000232210.13039/501100000780 |
container_title |
Transboundary and Emerging Diseases |
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69 |
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4 |
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