Sequential biocatalytic resolution of trans-cyclohexane-1,2-diamine. Chemoenzymatic Synthesis of an optically active polyamine

2 pages, 1 figure, 2 schemes, 1 table.-- PMID: 15278156 [PubMed].-- Available online Jun 28, 2004. A new enzymatic process is described. Different preparations of lipase B from Candida antarctica are able to catalyse Michael-type addition of secondary amines to acrylonitrile. This new reaction widen...

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Bibliographic Details
Published in:Chemical Communications
Main Authors: Torres, Oliver, Alfonso, Ignacio, Gotor, Vicente
Format: Article in Journal/Newspaper
Language:English
Published: Royal Society of Chemistry (UK) 2004
Subjects:
Online Access:http://hdl.handle.net/10261/26792
https://doi.org/10.1039/b402244k
Description
Summary:2 pages, 1 figure, 2 schemes, 1 table.-- PMID: 15278156 [PubMed].-- Available online Jun 28, 2004. A new enzymatic process is described. Different preparations of lipase B from Candida antarctica are able to catalyse Michael-type addition of secondary amines to acrylonitrile. This new reaction widens the applicability of these biocatalysts in organic synthesis. Peer reviewed