Testosterone and persistent organic pollutants in East Greenland male polar bears ( Ursus maritimus )
Legacy persistent organic pollutants (POPs) such as polychlorinated biphenyls (PCBs) are chemicals that undergo long-range transport to the Arctic. These chemicals possess endocrine disruptive properties raising concerns for development and reproduction. Here, we report the relationship between conc...
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Language: | English |
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2023
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Online Access: | https://curis.ku.dk/portal/da/publications/testosterone-and-persistent-organic-pollutants-in-east-greenland-male-polar-bears-ursus-maritimus(e3a099b7-235c-4f4b-ab46-8520a6544d9d).html https://doi.org/10.1016/j.heliyon.2023.e13263 https://curis.ku.dk/ws/files/346244306/1_s2.0_S240584402300470X_main.pdf |
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ftcopenhagenunip:oai:pure.atira.dk:publications/e3a099b7-235c-4f4b-ab46-8520a6544d9d 2024-06-09T07:43:56+00:00 Testosterone and persistent organic pollutants in East Greenland male polar bears ( Ursus maritimus ) Ciesielski, Tomasz M. Sonne, Christian Smette, Eli I. Villanger, Gro Dehli Styrishave, Bjarne Letcher, Robert J. Hitchcock, Daniel J. Dietz, Rune Jenssen, Bjørn M. 2023 application/pdf https://curis.ku.dk/portal/da/publications/testosterone-and-persistent-organic-pollutants-in-east-greenland-male-polar-bears-ursus-maritimus(e3a099b7-235c-4f4b-ab46-8520a6544d9d).html https://doi.org/10.1016/j.heliyon.2023.e13263 https://curis.ku.dk/ws/files/346244306/1_s2.0_S240584402300470X_main.pdf eng eng info:eu-repo/semantics/openAccess Ciesielski , T M , Sonne , C , Smette , E I , Villanger , G D , Styrishave , B , Letcher , R J , Hitchcock , D J , Dietz , R & Jenssen , B M 2023 , ' Testosterone and persistent organic pollutants in East Greenland male polar bears ( Ursus maritimus ) ' , Heliyon , vol. 9 , no. 3 , e13263 . https://doi.org/10.1016/j.heliyon.2023.e13263 Arctic Endocrine disruption PCBs POPs Reproductive organs Seasonal hormone levels article 2023 ftcopenhagenunip https://doi.org/10.1016/j.heliyon.2023.e13263 2024-05-16T11:29:29Z Legacy persistent organic pollutants (POPs) such as polychlorinated biphenyls (PCBs) are chemicals that undergo long-range transport to the Arctic. These chemicals possess endocrine disruptive properties raising concerns for development and reproduction. Here, we report the relationship between concentrations of testosterone (T) and persistent organic pollutant (POPs) in 40 East Greenland male polar bears (Ursus maritimus) sampled during January to September 1999–2001. The mean ± standard concentrations of blood T were 0.31 ± 0.49 (mean ± SD) ng/mL in juveniles/subadults (n = 22) and 3.58 ± 7.45 ng/mL in adults (n = 18). The ∑POP concentrations (mean ± SD) in adipose tissue were 8139 ± 2990 ng/g lipid weight (lw) in juveniles/subadults and 11,037 ± 3950 ng/g lw in adult males, respectively, of which Σpolychlorinated biphenyls (ΣPCBs) were found in highest concentrations. The variation in T concentrations explained by sampling date (season), biometrics and adipose tissue POP concentrations was explored using redundancy analysis (RDA). The results showed that age, body length, and adipose lipid content in adult males contributed (p = 0.02) to the variation in POP concentrations. However, although some significant relationships between individual organochlorine contaminants and T concentrations in both juveniles/subadults and adult polar bears were identified, no significant relationships (p = 0.32) between T and POP concentrations were identified by the RDAs. Our results suggest that confounders such as biometrics and reproductive status may mask the endocrine disruptive effects that POPs have on blood T levels in male polar bears, demonstrating why it can be difficult to detect effects on wildlife populations. Article in Journal/Newspaper Arctic East Greenland Greenland Ursus maritimus University of Copenhagen: Research Arctic Greenland Heliyon 9 3 e13263 |
institution |
Open Polar |
collection |
University of Copenhagen: Research |
op_collection_id |
ftcopenhagenunip |
language |
English |
topic |
Arctic Endocrine disruption PCBs POPs Reproductive organs Seasonal hormone levels |
spellingShingle |
Arctic Endocrine disruption PCBs POPs Reproductive organs Seasonal hormone levels Ciesielski, Tomasz M. Sonne, Christian Smette, Eli I. Villanger, Gro Dehli Styrishave, Bjarne Letcher, Robert J. Hitchcock, Daniel J. Dietz, Rune Jenssen, Bjørn M. Testosterone and persistent organic pollutants in East Greenland male polar bears ( Ursus maritimus ) |
topic_facet |
Arctic Endocrine disruption PCBs POPs Reproductive organs Seasonal hormone levels |
description |
Legacy persistent organic pollutants (POPs) such as polychlorinated biphenyls (PCBs) are chemicals that undergo long-range transport to the Arctic. These chemicals possess endocrine disruptive properties raising concerns for development and reproduction. Here, we report the relationship between concentrations of testosterone (T) and persistent organic pollutant (POPs) in 40 East Greenland male polar bears (Ursus maritimus) sampled during January to September 1999–2001. The mean ± standard concentrations of blood T were 0.31 ± 0.49 (mean ± SD) ng/mL in juveniles/subadults (n = 22) and 3.58 ± 7.45 ng/mL in adults (n = 18). The ∑POP concentrations (mean ± SD) in adipose tissue were 8139 ± 2990 ng/g lipid weight (lw) in juveniles/subadults and 11,037 ± 3950 ng/g lw in adult males, respectively, of which Σpolychlorinated biphenyls (ΣPCBs) were found in highest concentrations. The variation in T concentrations explained by sampling date (season), biometrics and adipose tissue POP concentrations was explored using redundancy analysis (RDA). The results showed that age, body length, and adipose lipid content in adult males contributed (p = 0.02) to the variation in POP concentrations. However, although some significant relationships between individual organochlorine contaminants and T concentrations in both juveniles/subadults and adult polar bears were identified, no significant relationships (p = 0.32) between T and POP concentrations were identified by the RDAs. Our results suggest that confounders such as biometrics and reproductive status may mask the endocrine disruptive effects that POPs have on blood T levels in male polar bears, demonstrating why it can be difficult to detect effects on wildlife populations. |
format |
Article in Journal/Newspaper |
author |
Ciesielski, Tomasz M. Sonne, Christian Smette, Eli I. Villanger, Gro Dehli Styrishave, Bjarne Letcher, Robert J. Hitchcock, Daniel J. Dietz, Rune Jenssen, Bjørn M. |
author_facet |
Ciesielski, Tomasz M. Sonne, Christian Smette, Eli I. Villanger, Gro Dehli Styrishave, Bjarne Letcher, Robert J. Hitchcock, Daniel J. Dietz, Rune Jenssen, Bjørn M. |
author_sort |
Ciesielski, Tomasz M. |
title |
Testosterone and persistent organic pollutants in East Greenland male polar bears ( Ursus maritimus ) |
title_short |
Testosterone and persistent organic pollutants in East Greenland male polar bears ( Ursus maritimus ) |
title_full |
Testosterone and persistent organic pollutants in East Greenland male polar bears ( Ursus maritimus ) |
title_fullStr |
Testosterone and persistent organic pollutants in East Greenland male polar bears ( Ursus maritimus ) |
title_full_unstemmed |
Testosterone and persistent organic pollutants in East Greenland male polar bears ( Ursus maritimus ) |
title_sort |
testosterone and persistent organic pollutants in east greenland male polar bears ( ursus maritimus ) |
publishDate |
2023 |
url |
https://curis.ku.dk/portal/da/publications/testosterone-and-persistent-organic-pollutants-in-east-greenland-male-polar-bears-ursus-maritimus(e3a099b7-235c-4f4b-ab46-8520a6544d9d).html https://doi.org/10.1016/j.heliyon.2023.e13263 https://curis.ku.dk/ws/files/346244306/1_s2.0_S240584402300470X_main.pdf |
geographic |
Arctic Greenland |
geographic_facet |
Arctic Greenland |
genre |
Arctic East Greenland Greenland Ursus maritimus |
genre_facet |
Arctic East Greenland Greenland Ursus maritimus |
op_source |
Ciesielski , T M , Sonne , C , Smette , E I , Villanger , G D , Styrishave , B , Letcher , R J , Hitchcock , D J , Dietz , R & Jenssen , B M 2023 , ' Testosterone and persistent organic pollutants in East Greenland male polar bears ( Ursus maritimus ) ' , Heliyon , vol. 9 , no. 3 , e13263 . https://doi.org/10.1016/j.heliyon.2023.e13263 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1016/j.heliyon.2023.e13263 |
container_title |
Heliyon |
container_volume |
9 |
container_issue |
3 |
container_start_page |
e13263 |
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1801372756156088320 |