Forensic and population genetic analyses of Danes, Greenlanders and Somalis typed with the Yfiler® Plus PCR amplification kit
Recently, the Yfiler(®) Plus PCR Amplification Kit (Yfiler(®) Plus, Thermo Fisher Scientific, Waltham, MA, USA) was introduced. Yfiler(®) Plus amplifies 27 Y-chromosomal short tandem repeat loci (Y-STRs) and adds ten new Y-STRs to those analysed with the commonly used AmpFlSTR(®) Yfiler(®) PCR Ampli...
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Online Access: | https://curis.ku.dk/portal/da/publications/forensic-and-population-genetic-analyses-of-danes-greenlanders-and-somalis-typed-with-the-yfiler-plus-pcr-amplification-kit(b6110a05-209f-49be-8dac-d5c6a0cfee9e).html https://doi.org/10.1016/j.fsigen.2015.02.006 |
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ftcopenhagenunip:oai:pure.atira.dk:publications/b6110a05-209f-49be-8dac-d5c6a0cfee9e 2024-02-27T08:41:11+00:00 Forensic and population genetic analyses of Danes, Greenlanders and Somalis typed with the Yfiler® Plus PCR amplification kit Olofsson, Jill Katharina Mogensen, Helle Smidt Buchard, Anders Børsting, Claus Morling, Niels 2015-05 https://curis.ku.dk/portal/da/publications/forensic-and-population-genetic-analyses-of-danes-greenlanders-and-somalis-typed-with-the-yfiler-plus-pcr-amplification-kit(b6110a05-209f-49be-8dac-d5c6a0cfee9e).html https://doi.org/10.1016/j.fsigen.2015.02.006 eng eng info:eu-repo/semantics/closedAccess Olofsson , J K , Mogensen , H S , Buchard , A , Børsting , C & Morling , N 2015 , ' Forensic and population genetic analyses of Danes, Greenlanders and Somalis typed with the Yfiler® Plus PCR amplification kit ' , Forensic Science International: Genetics , vol. 16 , pp. 232-236 . https://doi.org/10.1016/j.fsigen.2015.02.006 article 2015 ftcopenhagenunip https://doi.org/10.1016/j.fsigen.2015.02.006 2024-02-01T00:03:28Z Recently, the Yfiler(®) Plus PCR Amplification Kit (Yfiler(®) Plus, Thermo Fisher Scientific, Waltham, MA, USA) was introduced. Yfiler(®) Plus amplifies 27 Y-chromosomal short tandem repeat loci (Y-STRs) and adds ten new Y-STRs to those analysed with the commonly used AmpFlSTR(®) Yfiler(®) PCR Amplification Kit (Yfiler(®), Thermo Fisher Scientific, Waltham, MA, USA). Seven of the new Y-STRs are rapidly mutating Y-STRs (RM Y-STRs). In this study, 551 male individuals from Denmark, Greenland and Somalia were typed with Yfiler(®) Plus. The results were compared to those obtained with Yfiler(®) in the same individuals. Forensic and population genetic parameters were estimated for Yfiler(®) Plus. Yfiler(®) Plus had a higher power of discrimination than Yfiler(®) in all three populations. Compared to Yfiler(®), Yfiler(®) Plus offers increased power of discrimination, which is obviously an advantage in crime case investigations. However, the inclusion of seven RM Y-STRs in Yfiler(®) Plus makes it less attractive for relationship testing because of the relatively high combined mutation rate, approximately 15%. Article in Journal/Newspaper Greenland greenlander* University of Copenhagen: Research Greenland Forensic Science International: Genetics 16 232 236 |
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Open Polar |
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University of Copenhagen: Research |
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ftcopenhagenunip |
language |
English |
description |
Recently, the Yfiler(®) Plus PCR Amplification Kit (Yfiler(®) Plus, Thermo Fisher Scientific, Waltham, MA, USA) was introduced. Yfiler(®) Plus amplifies 27 Y-chromosomal short tandem repeat loci (Y-STRs) and adds ten new Y-STRs to those analysed with the commonly used AmpFlSTR(®) Yfiler(®) PCR Amplification Kit (Yfiler(®), Thermo Fisher Scientific, Waltham, MA, USA). Seven of the new Y-STRs are rapidly mutating Y-STRs (RM Y-STRs). In this study, 551 male individuals from Denmark, Greenland and Somalia were typed with Yfiler(®) Plus. The results were compared to those obtained with Yfiler(®) in the same individuals. Forensic and population genetic parameters were estimated for Yfiler(®) Plus. Yfiler(®) Plus had a higher power of discrimination than Yfiler(®) in all three populations. Compared to Yfiler(®), Yfiler(®) Plus offers increased power of discrimination, which is obviously an advantage in crime case investigations. However, the inclusion of seven RM Y-STRs in Yfiler(®) Plus makes it less attractive for relationship testing because of the relatively high combined mutation rate, approximately 15%. |
format |
Article in Journal/Newspaper |
author |
Olofsson, Jill Katharina Mogensen, Helle Smidt Buchard, Anders Børsting, Claus Morling, Niels |
spellingShingle |
Olofsson, Jill Katharina Mogensen, Helle Smidt Buchard, Anders Børsting, Claus Morling, Niels Forensic and population genetic analyses of Danes, Greenlanders and Somalis typed with the Yfiler® Plus PCR amplification kit |
author_facet |
Olofsson, Jill Katharina Mogensen, Helle Smidt Buchard, Anders Børsting, Claus Morling, Niels |
author_sort |
Olofsson, Jill Katharina |
title |
Forensic and population genetic analyses of Danes, Greenlanders and Somalis typed with the Yfiler® Plus PCR amplification kit |
title_short |
Forensic and population genetic analyses of Danes, Greenlanders and Somalis typed with the Yfiler® Plus PCR amplification kit |
title_full |
Forensic and population genetic analyses of Danes, Greenlanders and Somalis typed with the Yfiler® Plus PCR amplification kit |
title_fullStr |
Forensic and population genetic analyses of Danes, Greenlanders and Somalis typed with the Yfiler® Plus PCR amplification kit |
title_full_unstemmed |
Forensic and population genetic analyses of Danes, Greenlanders and Somalis typed with the Yfiler® Plus PCR amplification kit |
title_sort |
forensic and population genetic analyses of danes, greenlanders and somalis typed with the yfiler® plus pcr amplification kit |
publishDate |
2015 |
url |
https://curis.ku.dk/portal/da/publications/forensic-and-population-genetic-analyses-of-danes-greenlanders-and-somalis-typed-with-the-yfiler-plus-pcr-amplification-kit(b6110a05-209f-49be-8dac-d5c6a0cfee9e).html https://doi.org/10.1016/j.fsigen.2015.02.006 |
geographic |
Greenland |
geographic_facet |
Greenland |
genre |
Greenland greenlander* |
genre_facet |
Greenland greenlander* |
op_source |
Olofsson , J K , Mogensen , H S , Buchard , A , Børsting , C & Morling , N 2015 , ' Forensic and population genetic analyses of Danes, Greenlanders and Somalis typed with the Yfiler® Plus PCR amplification kit ' , Forensic Science International: Genetics , vol. 16 , pp. 232-236 . https://doi.org/10.1016/j.fsigen.2015.02.006 |
op_rights |
info:eu-repo/semantics/closedAccess |
op_doi |
https://doi.org/10.1016/j.fsigen.2015.02.006 |
container_title |
Forensic Science International: Genetics |
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16 |
container_start_page |
232 |
op_container_end_page |
236 |
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