Occupational exposure to solvents and bladder cancer:A population-based case control study in Nordic countries
The objective of the study was to assess the relationship between exposure to selected solvents and the risk of bladder cancer. This study is based on the Nordic Occupational Cancer (NOCCA) database and comprises 113,343 cases of bladder cancer diagnosed in Finland, Iceland, Norway and Sweden betwee...
Published in: | International Journal of Cancer |
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Format: | Article in Journal/Newspaper |
Language: | English |
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2017
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Online Access: | https://curis.ku.dk/portal/da/publications/occupational-exposure-to-solvents-and-bladder-cancer(afa95cfc-0351-4cd1-a11c-30f38644ab3f).html https://doi.org/10.1002/ijc.30593 |
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ftcopenhagenunip:oai:pure.atira.dk:publications/afa95cfc-0351-4cd1-a11c-30f38644ab3f 2023-12-17T10:32:09+01:00 Occupational exposure to solvents and bladder cancer:A population-based case control study in Nordic countries Hadkhale, Kishor Martinsen, Jan Ivar Weiderpass, Elisabete Kjaerheim, Kristina Sparen, Pär Tryggvadottir, Laufey Lynge, Elsebeth Pukkala, Eero 2017-04-15 https://curis.ku.dk/portal/da/publications/occupational-exposure-to-solvents-and-bladder-cancer(afa95cfc-0351-4cd1-a11c-30f38644ab3f).html https://doi.org/10.1002/ijc.30593 eng eng info:eu-repo/semantics/closedAccess Hadkhale , K , Martinsen , J I , Weiderpass , E , Kjaerheim , K , Sparen , P , Tryggvadottir , L , Lynge , E & Pukkala , E 2017 , ' Occupational exposure to solvents and bladder cancer : A population-based case control study in Nordic countries ' , International Journal of Cancer , vol. 140 , no. 8 , pp. 1736–1746 . https://doi.org/10.1002/ijc.30593 article 2017 ftcopenhagenunip https://doi.org/10.1002/ijc.30593 2023-11-23T00:01:11Z The objective of the study was to assess the relationship between exposure to selected solvents and the risk of bladder cancer. This study is based on the Nordic Occupational Cancer (NOCCA) database and comprises 113,343 cases of bladder cancer diagnosed in Finland, Iceland, Norway and Sweden between 1961 and 2005 and 566,715 population controls matched according to country, sex and birth year. Census-based occupational titles of the cases and controls were linked with the job exposure matrix created by the NOCCA project to estimate quantitative cumulative occupational exposures. A conditional logistic regression model was used to estimate hazard ratios (HR) and their 95% confidence intervals (95% CI). Increased risks were observed for trichloroethylene (HR 1.23, 95% 95% CI 1.12-1.40), toluene (HR 1.20, 95% CI 1.00-1.38), benzene (HR 1.16, 95% CI 1.04-1.31), aromatic hydrocarbon solvents (HR 1.10, 95% CI 0.94-1.30) and aliphatic & alicyclic hydrocarbon solvents (HR 1.08, 95% CI 1.00-1.23) at high exposure level versus no exposure. The highest excess for perchloroethylene was observed at medium exposure level (HR 1.12, 95% CI 1.02-1.23). The study provides evidence of an association of occupational exposure to trichloroethylene, perchloroethylene, aromatic hydrocarbon solvents, benzene and toluene and the risk of bladder cancer. The objective of the study was to assess the relationship between exposure to selected solvents and the risk of bladder cancer. This study is based on the Nordic Occupational Cancer (NOCCA) database and comprises 113,343 cases of bladder cancer diagnosed in Finland, Iceland, Norway and Sweden between 1961 and 2005 and 566,715 population controls matched according to country, sex and birth year. Census-based occupational titles of the cases and controls were linked with the job exposure matrix created by the NOCCA project to estimate quantitative cumulative occupational exposures. A conditional logistic regression model was used to estimate hazard ratios (HR) and their 95% confidence ... Article in Journal/Newspaper Iceland University of Copenhagen: Research Norway International Journal of Cancer 140 8 1736 1746 |
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Open Polar |
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University of Copenhagen: Research |
op_collection_id |
ftcopenhagenunip |
language |
English |
description |
The objective of the study was to assess the relationship between exposure to selected solvents and the risk of bladder cancer. This study is based on the Nordic Occupational Cancer (NOCCA) database and comprises 113,343 cases of bladder cancer diagnosed in Finland, Iceland, Norway and Sweden between 1961 and 2005 and 566,715 population controls matched according to country, sex and birth year. Census-based occupational titles of the cases and controls were linked with the job exposure matrix created by the NOCCA project to estimate quantitative cumulative occupational exposures. A conditional logistic regression model was used to estimate hazard ratios (HR) and their 95% confidence intervals (95% CI). Increased risks were observed for trichloroethylene (HR 1.23, 95% 95% CI 1.12-1.40), toluene (HR 1.20, 95% CI 1.00-1.38), benzene (HR 1.16, 95% CI 1.04-1.31), aromatic hydrocarbon solvents (HR 1.10, 95% CI 0.94-1.30) and aliphatic & alicyclic hydrocarbon solvents (HR 1.08, 95% CI 1.00-1.23) at high exposure level versus no exposure. The highest excess for perchloroethylene was observed at medium exposure level (HR 1.12, 95% CI 1.02-1.23). The study provides evidence of an association of occupational exposure to trichloroethylene, perchloroethylene, aromatic hydrocarbon solvents, benzene and toluene and the risk of bladder cancer. The objective of the study was to assess the relationship between exposure to selected solvents and the risk of bladder cancer. This study is based on the Nordic Occupational Cancer (NOCCA) database and comprises 113,343 cases of bladder cancer diagnosed in Finland, Iceland, Norway and Sweden between 1961 and 2005 and 566,715 population controls matched according to country, sex and birth year. Census-based occupational titles of the cases and controls were linked with the job exposure matrix created by the NOCCA project to estimate quantitative cumulative occupational exposures. A conditional logistic regression model was used to estimate hazard ratios (HR) and their 95% confidence ... |
format |
Article in Journal/Newspaper |
author |
Hadkhale, Kishor Martinsen, Jan Ivar Weiderpass, Elisabete Kjaerheim, Kristina Sparen, Pär Tryggvadottir, Laufey Lynge, Elsebeth Pukkala, Eero |
spellingShingle |
Hadkhale, Kishor Martinsen, Jan Ivar Weiderpass, Elisabete Kjaerheim, Kristina Sparen, Pär Tryggvadottir, Laufey Lynge, Elsebeth Pukkala, Eero Occupational exposure to solvents and bladder cancer:A population-based case control study in Nordic countries |
author_facet |
Hadkhale, Kishor Martinsen, Jan Ivar Weiderpass, Elisabete Kjaerheim, Kristina Sparen, Pär Tryggvadottir, Laufey Lynge, Elsebeth Pukkala, Eero |
author_sort |
Hadkhale, Kishor |
title |
Occupational exposure to solvents and bladder cancer:A population-based case control study in Nordic countries |
title_short |
Occupational exposure to solvents and bladder cancer:A population-based case control study in Nordic countries |
title_full |
Occupational exposure to solvents and bladder cancer:A population-based case control study in Nordic countries |
title_fullStr |
Occupational exposure to solvents and bladder cancer:A population-based case control study in Nordic countries |
title_full_unstemmed |
Occupational exposure to solvents and bladder cancer:A population-based case control study in Nordic countries |
title_sort |
occupational exposure to solvents and bladder cancer:a population-based case control study in nordic countries |
publishDate |
2017 |
url |
https://curis.ku.dk/portal/da/publications/occupational-exposure-to-solvents-and-bladder-cancer(afa95cfc-0351-4cd1-a11c-30f38644ab3f).html https://doi.org/10.1002/ijc.30593 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Hadkhale , K , Martinsen , J I , Weiderpass , E , Kjaerheim , K , Sparen , P , Tryggvadottir , L , Lynge , E & Pukkala , E 2017 , ' Occupational exposure to solvents and bladder cancer : A population-based case control study in Nordic countries ' , International Journal of Cancer , vol. 140 , no. 8 , pp. 1736–1746 . https://doi.org/10.1002/ijc.30593 |
op_rights |
info:eu-repo/semantics/closedAccess |
op_doi |
https://doi.org/10.1002/ijc.30593 |
container_title |
International Journal of Cancer |
container_volume |
140 |
container_issue |
8 |
container_start_page |
1736 |
op_container_end_page |
1746 |
_version_ |
1785585666795503616 |