The role of adrenaline as a modulator of cardiac performance in two Antarctic fishes
Abstract: The present work was performed to test the hypothesis that Antarctic teleosts rely mostly on cholinergic inhibition for autonomic modulation of the heart. The effects of adrenaline on the inotropic properties on paced, isometrically contracting muscle strips were examined in two distinct A...
Published in: | Polar Biology |
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Format: | Article in Journal/Newspaper |
Language: | English |
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2009
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Online Access: | https://curis.ku.dk/portal/da/publications/the-role-of-adrenaline-as-a-modulator-of-cardiac-performance-in-two-antarctic-fishes(7c4fc980-b355-11df-825b-000ea68e967b).html https://doi.org/10.1007/s00300-008-0522-0 |
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ftcopenhagenunip:oai:pure.atira.dk:publications/7c4fc980-b355-11df-825b-000ea68e967b 2023-05-15T13:48:15+02:00 The role of adrenaline as a modulator of cardiac performance in two Antarctic fishes Skov, Peter Vilhelm Bushnell, Peter G. Tirsgaard, Bjørn Steffensen, John Fleng 2009 https://curis.ku.dk/portal/da/publications/the-role-of-adrenaline-as-a-modulator-of-cardiac-performance-in-two-antarctic-fishes(7c4fc980-b355-11df-825b-000ea68e967b).html https://doi.org/10.1007/s00300-008-0522-0 eng eng info:eu-repo/semantics/restrictedAccess Skov , P V , Bushnell , P G , Tirsgaard , B & Steffensen , J F 2009 , ' The role of adrenaline as a modulator of cardiac performance in two Antarctic fishes ' , Polar Biology , vol. 32 , no. 2 , pp. 215-223 . https://doi.org/10.1007/s00300-008-0522-0 article 2009 ftcopenhagenunip https://doi.org/10.1007/s00300-008-0522-0 2022-02-24T00:05:27Z Abstract: The present work was performed to test the hypothesis that Antarctic teleosts rely mostly on cholinergic inhibition for autonomic modulation of the heart. The effects of adrenaline on the inotropic properties on paced, isometrically contracting muscle strips were examined in two distinct Antarctic teleosts, the haemoglobinless icefish Chaenocephalus aceratus and the red-blooded Notothenia coriiceps. All tissues examined revealed a negative force-frequency relationship. Under baseline conditions C. aceratus contracted with a force twice as great as that of N. coriiceps. While the degree to which ventricular tissues responded to adrenaline varied between species, adrenergic stimulation significantly increases myocyte contraction force in this group of fishes. Contraction and relaxation times were not significantly affected by adrenaline concentration while absolute rates of contraction were. Adrenergic stimulation does not enable tissues to achieve higher contraction frequencies, but is shown to be a potent modulator of contraction force. Article in Journal/Newspaper Antarc* Antarctic Icefish Polar Biology University of Copenhagen: Research Antarctic Polar Biology 32 2 215 223 |
institution |
Open Polar |
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University of Copenhagen: Research |
op_collection_id |
ftcopenhagenunip |
language |
English |
description |
Abstract: The present work was performed to test the hypothesis that Antarctic teleosts rely mostly on cholinergic inhibition for autonomic modulation of the heart. The effects of adrenaline on the inotropic properties on paced, isometrically contracting muscle strips were examined in two distinct Antarctic teleosts, the haemoglobinless icefish Chaenocephalus aceratus and the red-blooded Notothenia coriiceps. All tissues examined revealed a negative force-frequency relationship. Under baseline conditions C. aceratus contracted with a force twice as great as that of N. coriiceps. While the degree to which ventricular tissues responded to adrenaline varied between species, adrenergic stimulation significantly increases myocyte contraction force in this group of fishes. Contraction and relaxation times were not significantly affected by adrenaline concentration while absolute rates of contraction were. Adrenergic stimulation does not enable tissues to achieve higher contraction frequencies, but is shown to be a potent modulator of contraction force. |
format |
Article in Journal/Newspaper |
author |
Skov, Peter Vilhelm Bushnell, Peter G. Tirsgaard, Bjørn Steffensen, John Fleng |
spellingShingle |
Skov, Peter Vilhelm Bushnell, Peter G. Tirsgaard, Bjørn Steffensen, John Fleng The role of adrenaline as a modulator of cardiac performance in two Antarctic fishes |
author_facet |
Skov, Peter Vilhelm Bushnell, Peter G. Tirsgaard, Bjørn Steffensen, John Fleng |
author_sort |
Skov, Peter Vilhelm |
title |
The role of adrenaline as a modulator of cardiac performance in two Antarctic fishes |
title_short |
The role of adrenaline as a modulator of cardiac performance in two Antarctic fishes |
title_full |
The role of adrenaline as a modulator of cardiac performance in two Antarctic fishes |
title_fullStr |
The role of adrenaline as a modulator of cardiac performance in two Antarctic fishes |
title_full_unstemmed |
The role of adrenaline as a modulator of cardiac performance in two Antarctic fishes |
title_sort |
role of adrenaline as a modulator of cardiac performance in two antarctic fishes |
publishDate |
2009 |
url |
https://curis.ku.dk/portal/da/publications/the-role-of-adrenaline-as-a-modulator-of-cardiac-performance-in-two-antarctic-fishes(7c4fc980-b355-11df-825b-000ea68e967b).html https://doi.org/10.1007/s00300-008-0522-0 |
geographic |
Antarctic |
geographic_facet |
Antarctic |
genre |
Antarc* Antarctic Icefish Polar Biology |
genre_facet |
Antarc* Antarctic Icefish Polar Biology |
op_source |
Skov , P V , Bushnell , P G , Tirsgaard , B & Steffensen , J F 2009 , ' The role of adrenaline as a modulator of cardiac performance in two Antarctic fishes ' , Polar Biology , vol. 32 , no. 2 , pp. 215-223 . https://doi.org/10.1007/s00300-008-0522-0 |
op_rights |
info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1007/s00300-008-0522-0 |
container_title |
Polar Biology |
container_volume |
32 |
container_issue |
2 |
container_start_page |
215 |
op_container_end_page |
223 |
_version_ |
1766249024556367872 |