Cohort profile:Nordic Helicobacter Pylori eradication project (NordHePEP)
Purpose: This cohort description presents the Nordic Helicobacter Pylori Eradication Project (NordHePEP), a population-based cohort of patients having received eradication treatment for Helicobacter pylori (HP). The cohort is created with the main purpose of examining whether and to what extent HP e...
Published in: | Scandinavian Journal of Gastroenterology |
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Format: | Article in Journal/Newspaper |
Language: | English |
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2023
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Online Access: | https://curis.ku.dk/portal/da/publications/cohort-profile(54144afe-4d33-4624-afa8-0bfd8898f0b2).html https://doi.org/10.1080/00365521.2022.2144435 https://curis.ku.dk/ws/files/344710435/Fulltext.pdf |
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ftcopenhagenunip:oai:pure.atira.dk:publications/54144afe-4d33-4624-afa8-0bfd8898f0b2 2024-06-09T07:47:11+00:00 Cohort profile:Nordic Helicobacter Pylori eradication project (NordHePEP) Pettersson, Anna Klara Santoni, Giola Yan, Jacinth Radkiewicz, Cecilia Xie, Shaohua Birgisson, Helgi Ness-Jensen, Eivind von Euler-Chelpin, My Kauppila, Joonas H. Lagergren, Jesper 2023 application/pdf https://curis.ku.dk/portal/da/publications/cohort-profile(54144afe-4d33-4624-afa8-0bfd8898f0b2).html https://doi.org/10.1080/00365521.2022.2144435 https://curis.ku.dk/ws/files/344710435/Fulltext.pdf eng eng info:eu-repo/semantics/openAccess Pettersson , A K , Santoni , G , Yan , J , Radkiewicz , C , Xie , S , Birgisson , H , Ness-Jensen , E , von Euler-Chelpin , M , Kauppila , J H & Lagergren , J 2023 , ' Cohort profile : Nordic Helicobacter Pylori eradication project (NordHePEP) ' , Scandinavian Journal of Gastroenterology , vol. 58 , no. 5 , pp. 453-459 . https://doi.org/10.1080/00365521.2022.2144435 gastrointestinal cancer Helicobacter pylori helicobacter pylori eradication multi-national outcomes population-based Scandinavia article 2023 ftcopenhagenunip https://doi.org/10.1080/00365521.2022.2144435 2024-05-16T11:29:28Z Purpose: This cohort description presents the Nordic Helicobacter Pylori Eradication Project (NordHePEP), a population-based cohort of patients having received eradication treatment for Helicobacter pylori (HP). The cohort is created with the main purpose of examining whether and to what extent HP eradication treatment influences the risk of gastrointestinal cancer. Participants: NordHePEP includes all adults (aged ≥18 years) having been prescribed and dispensed HP eradication treatment according to the nationwide complete drug registries in any of the five Nordic countries (Denmark, Finland, Iceland, Norway, or Sweden) between 1994 and 2020 (start and end year varies between countries). We have retrieved and merged individual-level data from multiple national registries, including drug, patient, cancer, population, and death registries. Findings: The cohort includes 674,771 patients having received HP eradication treatment. During up to 23 years of follow-up, 59,292 (8.8%) participants were diagnosed with cancer (non-melanoma skin cancer excluded), whereof 15,496 (2.3%) in the gastrointestinal tract. Future plans: We will analyse HP eradication treatment in relation to gastrointestinal cancer risk. Standardised incidence ratios will be calculated as the observed cancer incidence in the cohort divided by the expected cancer incidence, derived from the background population of the corresponding age, sex, and calendar year. Article in Journal/Newspaper Iceland University of Copenhagen: Research Norway Scandinavian Journal of Gastroenterology 58 5 453 459 |
institution |
Open Polar |
collection |
University of Copenhagen: Research |
op_collection_id |
ftcopenhagenunip |
language |
English |
topic |
gastrointestinal cancer Helicobacter pylori helicobacter pylori eradication multi-national outcomes population-based Scandinavia |
spellingShingle |
gastrointestinal cancer Helicobacter pylori helicobacter pylori eradication multi-national outcomes population-based Scandinavia Pettersson, Anna Klara Santoni, Giola Yan, Jacinth Radkiewicz, Cecilia Xie, Shaohua Birgisson, Helgi Ness-Jensen, Eivind von Euler-Chelpin, My Kauppila, Joonas H. Lagergren, Jesper Cohort profile:Nordic Helicobacter Pylori eradication project (NordHePEP) |
topic_facet |
gastrointestinal cancer Helicobacter pylori helicobacter pylori eradication multi-national outcomes population-based Scandinavia |
description |
Purpose: This cohort description presents the Nordic Helicobacter Pylori Eradication Project (NordHePEP), a population-based cohort of patients having received eradication treatment for Helicobacter pylori (HP). The cohort is created with the main purpose of examining whether and to what extent HP eradication treatment influences the risk of gastrointestinal cancer. Participants: NordHePEP includes all adults (aged ≥18 years) having been prescribed and dispensed HP eradication treatment according to the nationwide complete drug registries in any of the five Nordic countries (Denmark, Finland, Iceland, Norway, or Sweden) between 1994 and 2020 (start and end year varies between countries). We have retrieved and merged individual-level data from multiple national registries, including drug, patient, cancer, population, and death registries. Findings: The cohort includes 674,771 patients having received HP eradication treatment. During up to 23 years of follow-up, 59,292 (8.8%) participants were diagnosed with cancer (non-melanoma skin cancer excluded), whereof 15,496 (2.3%) in the gastrointestinal tract. Future plans: We will analyse HP eradication treatment in relation to gastrointestinal cancer risk. Standardised incidence ratios will be calculated as the observed cancer incidence in the cohort divided by the expected cancer incidence, derived from the background population of the corresponding age, sex, and calendar year. |
format |
Article in Journal/Newspaper |
author |
Pettersson, Anna Klara Santoni, Giola Yan, Jacinth Radkiewicz, Cecilia Xie, Shaohua Birgisson, Helgi Ness-Jensen, Eivind von Euler-Chelpin, My Kauppila, Joonas H. Lagergren, Jesper |
author_facet |
Pettersson, Anna Klara Santoni, Giola Yan, Jacinth Radkiewicz, Cecilia Xie, Shaohua Birgisson, Helgi Ness-Jensen, Eivind von Euler-Chelpin, My Kauppila, Joonas H. Lagergren, Jesper |
author_sort |
Pettersson, Anna Klara |
title |
Cohort profile:Nordic Helicobacter Pylori eradication project (NordHePEP) |
title_short |
Cohort profile:Nordic Helicobacter Pylori eradication project (NordHePEP) |
title_full |
Cohort profile:Nordic Helicobacter Pylori eradication project (NordHePEP) |
title_fullStr |
Cohort profile:Nordic Helicobacter Pylori eradication project (NordHePEP) |
title_full_unstemmed |
Cohort profile:Nordic Helicobacter Pylori eradication project (NordHePEP) |
title_sort |
cohort profile:nordic helicobacter pylori eradication project (nordhepep) |
publishDate |
2023 |
url |
https://curis.ku.dk/portal/da/publications/cohort-profile(54144afe-4d33-4624-afa8-0bfd8898f0b2).html https://doi.org/10.1080/00365521.2022.2144435 https://curis.ku.dk/ws/files/344710435/Fulltext.pdf |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Pettersson , A K , Santoni , G , Yan , J , Radkiewicz , C , Xie , S , Birgisson , H , Ness-Jensen , E , von Euler-Chelpin , M , Kauppila , J H & Lagergren , J 2023 , ' Cohort profile : Nordic Helicobacter Pylori eradication project (NordHePEP) ' , Scandinavian Journal of Gastroenterology , vol. 58 , no. 5 , pp. 453-459 . https://doi.org/10.1080/00365521.2022.2144435 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1080/00365521.2022.2144435 |
container_title |
Scandinavian Journal of Gastroenterology |
container_volume |
58 |
container_issue |
5 |
container_start_page |
453 |
op_container_end_page |
459 |
_version_ |
1801378126698119168 |