Salmon gut microbiota correlates with disease infection status:potential for monitoring health in farmed animals
Background Infectious diseases cause significant production losses in aquaculture every year. Since the gut microbiota plays an essential role in regulating the host immune system, health and physiology, altered gut microbiota compositions are often associated with a diseased status. However, few st...
Published in: | Animal Microbiome |
---|---|
Main Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
2021
|
Subjects: | |
Online Access: | https://curis.ku.dk/portal/da/publications/salmon-gut-microbiota-correlates-with-disease-infection-status(18fa85fb-dfd3-454f-ab8a-d9b6fac8d3c2).html https://doi.org/10.1186/s42523-021-00096-2 https://curis.ku.dk/ws/files/272071575/Salmon_gut_microbiota_correlates_with_disease_infection_status.pdf |
id |
ftcopenhagenunip:oai:pure.atira.dk:publications/18fa85fb-dfd3-454f-ab8a-d9b6fac8d3c2 |
---|---|
record_format |
openpolar |
spelling |
ftcopenhagenunip:oai:pure.atira.dk:publications/18fa85fb-dfd3-454f-ab8a-d9b6fac8d3c2 2024-06-09T07:44:48+00:00 Salmon gut microbiota correlates with disease infection status:potential for monitoring health in farmed animals Bozzi, Davide Rasmussen, Jacob Agerbo Carøe, Christian Sveier, Harald Nordøy, Kristian Gilbert, M Thomas P Limborg, Morten T. 2021 application/pdf https://curis.ku.dk/portal/da/publications/salmon-gut-microbiota-correlates-with-disease-infection-status(18fa85fb-dfd3-454f-ab8a-d9b6fac8d3c2).html https://doi.org/10.1186/s42523-021-00096-2 https://curis.ku.dk/ws/files/272071575/Salmon_gut_microbiota_correlates_with_disease_infection_status.pdf eng eng info:eu-repo/semantics/openAccess Bozzi , D , Rasmussen , J A , Carøe , C , Sveier , H , Nordøy , K , Gilbert , M T P & Limborg , M T 2021 , ' Salmon gut microbiota correlates with disease infection status : potential for monitoring health in farmed animals ' , BMC Animal Microbiome , vol. 3 , no. 1 , 30 . https://doi.org/10.1186/s42523-021-00096-2 Aliivibrio Atlantic salmon Biomarkers Dysbiosis Fish growth Infectious diseases Microbiota Mycoplasma Tenacibaculosis article 2021 ftcopenhagenunip https://doi.org/10.1186/s42523-021-00096-2 2024-05-16T11:29:20Z Background Infectious diseases cause significant production losses in aquaculture every year. Since the gut microbiota plays an essential role in regulating the host immune system, health and physiology, altered gut microbiota compositions are often associated with a diseased status. However, few studies have examined the association between disease severity and degree of gut dysbiosis, especially when the gut is not the site of the primary infection. Moreover, there is a lack of knowledge on whether bath treatment with formalin, a disinfectant commonly used in aquaculture to treat external infections, might affect the gut microbiome as a consequence of formalin ingestion. Here we investigate, through 16S rRNA gene metabarcoding, changes in the distal gut microbiota composition of a captive-reared cohort of 80 Atlantic salmon (Salmo salar L.), in consequence of an external bacterial skin infection due to a natural outbreak and subsequent formalin treatment. Results We identified Tenacibaculum dicentrarchi as the causative disease pathogen and we show that the distal gut of diseased salmon presented a different composition from that of healthy individuals. A new, yet undescribed, Mycoplasma genus characterized the gut of healthy salmon, while in the sick fish we observed an increase in terms of relative abundance of Aliivibrio sp., a strain regarded as opportunistic. We also noticed a positive correlation between fish weight and Mycoplasma sp. relative abundance, potentially indicating a beneficial effect for its host. Moreover, we observed that the gut microbiota of fish treated with formalin was more similar to those of sick fish than healthy ones. Conclusions We conclude that external Tenacibaculum infections have the potential of indirectly affecting the host gut microbiota. As such, treatment optimization procedures should account for that. Formalin treatment is not an optimal solution from a holistic perspective, since we observe an altered gut microbiota in the treated fish. We suggest its coupling with a ... Article in Journal/Newspaper Atlantic salmon Salmo salar University of Copenhagen: Research Animal Microbiome 3 1 |
institution |
Open Polar |
collection |
University of Copenhagen: Research |
op_collection_id |
ftcopenhagenunip |
language |
English |
topic |
Aliivibrio Atlantic salmon Biomarkers Dysbiosis Fish growth Infectious diseases Microbiota Mycoplasma Tenacibaculosis |
spellingShingle |
Aliivibrio Atlantic salmon Biomarkers Dysbiosis Fish growth Infectious diseases Microbiota Mycoplasma Tenacibaculosis Bozzi, Davide Rasmussen, Jacob Agerbo Carøe, Christian Sveier, Harald Nordøy, Kristian Gilbert, M Thomas P Limborg, Morten T. Salmon gut microbiota correlates with disease infection status:potential for monitoring health in farmed animals |
topic_facet |
Aliivibrio Atlantic salmon Biomarkers Dysbiosis Fish growth Infectious diseases Microbiota Mycoplasma Tenacibaculosis |
description |
Background Infectious diseases cause significant production losses in aquaculture every year. Since the gut microbiota plays an essential role in regulating the host immune system, health and physiology, altered gut microbiota compositions are often associated with a diseased status. However, few studies have examined the association between disease severity and degree of gut dysbiosis, especially when the gut is not the site of the primary infection. Moreover, there is a lack of knowledge on whether bath treatment with formalin, a disinfectant commonly used in aquaculture to treat external infections, might affect the gut microbiome as a consequence of formalin ingestion. Here we investigate, through 16S rRNA gene metabarcoding, changes in the distal gut microbiota composition of a captive-reared cohort of 80 Atlantic salmon (Salmo salar L.), in consequence of an external bacterial skin infection due to a natural outbreak and subsequent formalin treatment. Results We identified Tenacibaculum dicentrarchi as the causative disease pathogen and we show that the distal gut of diseased salmon presented a different composition from that of healthy individuals. A new, yet undescribed, Mycoplasma genus characterized the gut of healthy salmon, while in the sick fish we observed an increase in terms of relative abundance of Aliivibrio sp., a strain regarded as opportunistic. We also noticed a positive correlation between fish weight and Mycoplasma sp. relative abundance, potentially indicating a beneficial effect for its host. Moreover, we observed that the gut microbiota of fish treated with formalin was more similar to those of sick fish than healthy ones. Conclusions We conclude that external Tenacibaculum infections have the potential of indirectly affecting the host gut microbiota. As such, treatment optimization procedures should account for that. Formalin treatment is not an optimal solution from a holistic perspective, since we observe an altered gut microbiota in the treated fish. We suggest its coupling with a ... |
format |
Article in Journal/Newspaper |
author |
Bozzi, Davide Rasmussen, Jacob Agerbo Carøe, Christian Sveier, Harald Nordøy, Kristian Gilbert, M Thomas P Limborg, Morten T. |
author_facet |
Bozzi, Davide Rasmussen, Jacob Agerbo Carøe, Christian Sveier, Harald Nordøy, Kristian Gilbert, M Thomas P Limborg, Morten T. |
author_sort |
Bozzi, Davide |
title |
Salmon gut microbiota correlates with disease infection status:potential for monitoring health in farmed animals |
title_short |
Salmon gut microbiota correlates with disease infection status:potential for monitoring health in farmed animals |
title_full |
Salmon gut microbiota correlates with disease infection status:potential for monitoring health in farmed animals |
title_fullStr |
Salmon gut microbiota correlates with disease infection status:potential for monitoring health in farmed animals |
title_full_unstemmed |
Salmon gut microbiota correlates with disease infection status:potential for monitoring health in farmed animals |
title_sort |
salmon gut microbiota correlates with disease infection status:potential for monitoring health in farmed animals |
publishDate |
2021 |
url |
https://curis.ku.dk/portal/da/publications/salmon-gut-microbiota-correlates-with-disease-infection-status(18fa85fb-dfd3-454f-ab8a-d9b6fac8d3c2).html https://doi.org/10.1186/s42523-021-00096-2 https://curis.ku.dk/ws/files/272071575/Salmon_gut_microbiota_correlates_with_disease_infection_status.pdf |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
Bozzi , D , Rasmussen , J A , Carøe , C , Sveier , H , Nordøy , K , Gilbert , M T P & Limborg , M T 2021 , ' Salmon gut microbiota correlates with disease infection status : potential for monitoring health in farmed animals ' , BMC Animal Microbiome , vol. 3 , no. 1 , 30 . https://doi.org/10.1186/s42523-021-00096-2 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1186/s42523-021-00096-2 |
container_title |
Animal Microbiome |
container_volume |
3 |
container_issue |
1 |
_version_ |
1801373621431566336 |