Biocatalytic synthesis of chiral N-(2-hydroxyalkyl)-acrylamides
The preparation of a series of novel chiral N-(2-hydroxylalkyl)-acrylamides through a lipase-catalyzed resolution of racemic alkanolamines is described. The absolute stereochemistry and enantiomeric excess of the products were determined by a modified Mosher's method. The method was validated f...
| Published in: | Biocatalysis and Biotransformation |
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| Main Authors: | , , |
| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
Taylor & Francis Ltd
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| Subjects: | |
| Online Access: | http://hdl.handle.net/11336/84703 |