Microbial hydrolysis of acetylated nucleosides
Enzymatic hydrolysis of acetylated nucleosides using microbial whole cells has been carried out for the first time. Unlike Candida antarctica B lipase-catalysed alcoholysis, none of the tested microorganisms displayed a common deacetylation profile. Depending on the substrate and the biocatalyst use...
| Published in: | Biotechnology Letters |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
Springer
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/11336/79655 |
| _version_ | 1821760742521569280 |
|---|---|
| author | Panero, Julieta Trelles, Jorge Abel Rodano, Valeria Montserrat, Javier Marcelo Iglesias, Luis Emilio Lewkowicz, Elizabeth Sandra Iribarren, Adolfo Marcelo |
| author_facet | Panero, Julieta Trelles, Jorge Abel Rodano, Valeria Montserrat, Javier Marcelo Iglesias, Luis Emilio Lewkowicz, Elizabeth Sandra Iribarren, Adolfo Marcelo |
| author_sort | Panero, Julieta |
| collection | CONICET Digital (Consejo Nacional de Investigaciones Científicas y Técnicas) |
| container_issue | 14 |
| container_start_page | 1077 |
| container_title | Biotechnology Letters |
| container_volume | 28 |
| description | Enzymatic hydrolysis of acetylated nucleosides using microbial whole cells has been carried out for the first time. Unlike Candida antarctica B lipase-catalysed alcoholysis, none of the tested microorganisms displayed a common deacetylation profile. Depending on the substrate and the biocatalyst used, 5′-selective deprotection or mixtures of mono O-acetylated products were obtained. Fil: Panero, Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes; Argentina Fil: Trelles, Jorge Abel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes; Argentina Fil: Rodano, Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina Fil: Montserrat, Javier Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina. Universidad Nacional de General Sarmiento. Instituto de Ciencias; Argentina Fil: Iglesias, Luis Emilio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes; Argentina Fil: Lewkowicz, Elizabeth Sandra. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes; Argentina Fil: Iribarren, Adolfo Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina |
| format | Article in Journal/Newspaper |
| genre | Antarc* Antarctica |
| genre_facet | Antarc* Antarctica |
| geographic | Argentina Sarmiento Julieta Quilmes |
| geographic_facet | Argentina Sarmiento Julieta Quilmes |
| id | ftconicet:oai:ri.conicet.gov.ar:11336/79655 |
| institution | Open Polar |
| language | English |
| long_lat | ENVELOPE(-68.000,-68.000,-72.000,-72.000) ENVELOPE(-61.358,-61.358,-64.397,-64.397) ENVELOPE(-55.617,-55.617,-63.233,-63.233) |
| op_collection_id | ftconicet |
| op_container_end_page | 1081 |
| op_doi | https://doi.org/10.1007/s10529-006-9053-3 |
| op_relation | info:eu-repo/semantics/altIdentifier/doi/10.1007/s10529-006-9053-3 info:eu-repo/semantics/altIdentifier/url/link.springer.com/article/10.1007/s10529-006-9053-3 http://hdl.handle.net/11336/79655 Panero, Julieta; Trelles, Jorge Abel; Rodano, Valeria; Montserrat, Javier Marcelo; Iglesias, Luis Emilio; et al.; Microbial hydrolysis of acetylated nucleosides; Springer; Biotechnology Letters; 28; 14; 7-2006; 1077-1081 0141-5492 CONICET Digital CONICET |
| op_rights | info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
| publisher | Springer |
| record_format | openpolar |
| spelling | ftconicet:oai:ri.conicet.gov.ar:11336/79655 2025-01-16T19:28:35+00:00 Microbial hydrolysis of acetylated nucleosides Panero, Julieta Trelles, Jorge Abel Rodano, Valeria Montserrat, Javier Marcelo Iglesias, Luis Emilio Lewkowicz, Elizabeth Sandra Iribarren, Adolfo Marcelo application/pdf http://hdl.handle.net/11336/79655 eng eng Springer info:eu-repo/semantics/altIdentifier/doi/10.1007/s10529-006-9053-3 info:eu-repo/semantics/altIdentifier/url/link.springer.com/article/10.1007/s10529-006-9053-3 http://hdl.handle.net/11336/79655 Panero, Julieta; Trelles, Jorge Abel; Rodano, Valeria; Montserrat, Javier Marcelo; Iglesias, Luis Emilio; et al.; Microbial hydrolysis of acetylated nucleosides; Springer; Biotechnology Letters; 28; 14; 7-2006; 1077-1081 0141-5492 CONICET Digital CONICET info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ Deacylation Hydrolases Nucleosides Whole Cells https://purl.org/becyt/ford/2.9 https://purl.org/becyt/ford/2 info:eu-repo/semantics/article info:ar-repo/semantics/artículo info:eu-repo/semantics/publishedVersion ftconicet https://doi.org/10.1007/s10529-006-9053-3 2023-09-24T19:38:30Z Enzymatic hydrolysis of acetylated nucleosides using microbial whole cells has been carried out for the first time. Unlike Candida antarctica B lipase-catalysed alcoholysis, none of the tested microorganisms displayed a common deacetylation profile. Depending on the substrate and the biocatalyst used, 5′-selective deprotection or mixtures of mono O-acetylated products were obtained. Fil: Panero, Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes; Argentina Fil: Trelles, Jorge Abel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes; Argentina Fil: Rodano, Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina Fil: Montserrat, Javier Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina. Universidad Nacional de General Sarmiento. Instituto de Ciencias; Argentina Fil: Iglesias, Luis Emilio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes; Argentina Fil: Lewkowicz, Elizabeth Sandra. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes; Argentina Fil: Iribarren, Adolfo Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina Article in Journal/Newspaper Antarc* Antarctica CONICET Digital (Consejo Nacional de Investigaciones Científicas y Técnicas) Argentina Sarmiento ENVELOPE(-68.000,-68.000,-72.000,-72.000) Julieta ENVELOPE(-61.358,-61.358,-64.397,-64.397) Quilmes ENVELOPE(-55.617,-55.617,-63.233,-63.233) Biotechnology Letters 28 14 1077 1081 |
| spellingShingle | Deacylation Hydrolases Nucleosides Whole Cells https://purl.org/becyt/ford/2.9 https://purl.org/becyt/ford/2 Panero, Julieta Trelles, Jorge Abel Rodano, Valeria Montserrat, Javier Marcelo Iglesias, Luis Emilio Lewkowicz, Elizabeth Sandra Iribarren, Adolfo Marcelo Microbial hydrolysis of acetylated nucleosides |
| title | Microbial hydrolysis of acetylated nucleosides |
| title_full | Microbial hydrolysis of acetylated nucleosides |
| title_fullStr | Microbial hydrolysis of acetylated nucleosides |
| title_full_unstemmed | Microbial hydrolysis of acetylated nucleosides |
| title_short | Microbial hydrolysis of acetylated nucleosides |
| title_sort | microbial hydrolysis of acetylated nucleosides |
| topic | Deacylation Hydrolases Nucleosides Whole Cells https://purl.org/becyt/ford/2.9 https://purl.org/becyt/ford/2 |
| topic_facet | Deacylation Hydrolases Nucleosides Whole Cells https://purl.org/becyt/ford/2.9 https://purl.org/becyt/ford/2 |
| url | http://hdl.handle.net/11336/79655 |