Lipase-catalyzed regioselective preparation of fatty acid esters of hydrocortisone

• Published in: Steroids
• Main Authors: Quintana, Paula Gabriela, Baldessari, Alicia
• Format: Article in Journal/Newspaper
• Language: English
• Published: Elsevier Science Inc
• Subjects: Hydrocortisone Fatty Acid Esters; Lipase-Catalyzed Reactions; https://purl.org/becyt/ford/1.4; https://purl.org/becyt/ford/1; Argentina; Alicia; Antarc*; Antarctica
• Online Access: http://hdl.handle.net/11336/70793

A series of fatty acid derivatives of hydrocortisone has been prepared by an enzymatic methodology. Nine 21-monoacyl products and one 3,11,17-triacetyl derivative, nine of them novel compounds, were obtained in a highly regioselective way through lipase-catalyzed esterification, transesterification...