Arctic char ( Salvelinus alpinus ) metallothionein: cDNA sequence, expression, and tissue-specific inhibition of cadmium-mediated metallothionein induction by 17β-estradiol, 4-OH-PCB 30, and PCB 104

• Published in: Environmental Toxicology and Chemistry
• Main Authors: Gerpe, Marcela Silvia, Kling, Peter, Berg, Axel Håkan, Olsson, Per Erik
• Format: Article in Journal/Newspaper
• Language: English
• Published: Society of Environmental Toxicology and Chemistry
• Subjects: Metallothionein; Arcticchar; Estrogen; Polychlorinated Biphenyls; Toxicology; https://purl.org/becyt/ford/1.5; https://purl.org/becyt/ford/1; Arctic; Argentina; Lambda; Suecia; Silvia; Salvelinus alpinus
• Online Access: http://hdl.handle.net/11336/69163

In this study, we haveexamined the basallevel expression and tissue‐specificexpressionpatternsof metallothionein (MT) in Arctic char following metal and E2 (17β‐estradiol) treatment. To study the gene regulation in Arctic char, the two MT isoforms were isolated from a lambda‐ZAP hepatic cDNA library...