Prospecting biotechnologically-relevant monooxygenases from cold sediment metagenomes: An in silico approach

• Published in: Marine Drugs
• Main Authors: Lozada, Mariana, Rial, Daniela Veronica, Mac Cormack, Walter Patricio, Jansson, Janet K., Sjöling, Sara, Carroll, JoLynn, Dionisi, Hebe Monica
• Format: Article in Journal/Newspaper
• Language: English
• Published: Molecular Diversity Preservation International
• Subjects: BACTERIAL CYTOCHROME P450; BAEYER-VILLIGER MONOOXYGENASES; BIOPROSPECTING BIOCATALYSTS; MOLECULAR MODELING; PHYLOGENETIC ANALYSIS; Otras Ciencias Biológicas; Ciencias Biológicas; CIENCIAS NATURALES Y EXACTAS; Arctic; Argentina; Argentino; Carroll; Noruega; Norway; Pacific; Rosario; Suecia; Dirección Nacional del Antártico; Instituto Antártico Argentino; Arctic University of Norway; UiT The Arctic University of Norway
• Online Access: http://hdl.handle.net/11336/39169

The goal of this work was to identify sequences encoding monooxygenase biocatalysts with novel features by in silico mining an assembled metagenomic dataset of polar and subpolar marine sediments. The targeted enzyme sequences were Baeyer-Villiger and bacterial cytochrome P450 monooxygenases (CYP153...