Enzymatic regioselective and complete deacetylation of two arabinonucleosides

• Published in: Journal of Molecular Catalysis B: Enzymatic
• Main Authors: Sabaini, María Belén, Zinni, María A., Mohorčič, Martina, Friedrich, Jožefa, Iribarren, Adolfo Marcelo, Iglesias, Luis Emilio
• Format: Article in Journal/Newspaper
• Language: English
• Published: Elsevier Science
• Subjects: KERATINASE; LIPASE; NUCLEOSIDES; PRODRUGS; REGIOSELECTIVITY; https://purl.org/becyt/ford/1.4; https://purl.org/becyt/ford/1; Argentina; Martina; Quilmes; Antarc*; Antarctica
• Online Access: http://hdl.handle.net/11336/190764

Candida antarctica lipase B (CAL-B)-catalysed regioselective deacetylation of 2′,3′,5′-tri- O-acetyl-1-β- d-arabinofuranosyluracil (1) and 2′,3′,5′-tri- O-acetyl-9-β- d-arabinofuranosyladenine (2) was studied. The choice of the reaction medium allowed the regioselective formation of products bearing...