Candida antarctica B lipase-catalysed alcoholysis of peracetylated alkyl D-ribofuranosides

• Published in: Biocatalysis and Biotransformation
• Main Authors: Gudiño, Esteban Dario, Iribarren, Adolfo Marcelo, Iglesias, Luis Emilio
• Format: Article in Journal/Newspaper
• Language: English
• Published: Taylor & Francis Ltd
• Subjects: CANDIDA ANTARCTICA B LIPASE; ENZYMATIC ALCOHOLYSIS; REGIOSELECTIVITY; RIBOFURANOSIDES; https://purl.org/becyt/ford/1.4; https://purl.org/becyt/ford/1; Argentina; Quilmes; Antarc*; Antarctica
• Online Access: http://hdl.handle.net/11336/189580

Candida antarctica B lipase (CAL-B) catalysed alcoholysis of a series of peracetylated alkyl α, β-D-ribofuranosides was assayed. Methyl and ethyl 2,3-di-O-acetyl-α, β-D-ribofuranosides enriched in the α-anomer were regioselectively prepared through this enzymatic deacetylation in 33% and 43% yield,...