Tissue Distribution of Microcystins in Bighead Carp via Intraperitoneal Injection

• Main Authors: S. Li, Æ P. Xie, Æ J. Xu, Æ L. Li, Æ G. Liang, Æ L. Zheng
• Other Authors: The Pennsylvania State University CiteSeerX Archives
• Format: Text
• Language: English
• Subjects: Atlantic salmon
• Online Access: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.657.42; http://159.226.163.151/bitstream/152342/8458/1/Tissue+distribution+of+microcystins+in+bighead+carp+via+intraperitoneal+injection.pdf

Hepatotoxic microcystins (MCs) are natural toxins produced by freshwater cyanobacteria such as Microcystis, Anabaena, Oscillatoria and Nostoc (Carmichael 2001). It can cause illness and death in wild and domestic animals and humans (Jochimsen et al. 1998; Zimba et al. 2001). Fishes, as higher trophic consumers, are known to accumulate microcystins. Many toxic experimental studies in fish were focused on documenting the toxicity of microcystin exposure through gastrointestinal and blood circular systems. There were only a few studies considering the tissue distribution and depu-ration of microcystin in fish (Williams et al. 1995, 1997; Tencalia and Dietrich 1997; Bury et al. 1998; Xie et al. 2004). Acute or subchronic toxic experiments have been conducted to study tissue distribution of microcystin on cold-water carnivorous fishes such as Atlantic salmon (Williams