Positional Specificity of Gastric Hydrolysis of Long-Chain n-3 Polyunsaturated Fatty Acids of Seal Milk Triglycerides 1

• Main Authors: Sara J. Iversona, Joseph Sampugna B, Olav T. Oftedal A
• Other Authors: The Pennsylvania State University CiteSeerX Archives
• Format: Text
• Language: English
• Subjects: Harp Seal; hooded seal
• Online Access: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.654.1579; http://fatlab.biology.dal.ca/wp-content/uploads/2013/06/Iverson_etal.PosSpec.Lipids_1992.pdf

Long-chain n-3 polyunsaturated fatty acids (n-3 PUFA) of marine oils are important dietary components for both infants and adults, and are incorporated into mlUo ~ follow-ing maternal dietary intake. However, little is known about the hydrolysis of these PUFA from milk triglycer-ides (TG) by lipases in suckling young. Seals, like human~, possess gastric lipase; however, the milk lipids of seals and sea lions are almost devoid of the readily hydrolyzable medium,chain fatty acids, and are characterized by a large percentage (10-30%) of n-3 PUFA. Gastric hydrolysis of milk lipids was studied in vivo in suckling pups of three species (the California sea lion, the harp seal and the hooded seal) in order to elucidate the actions and specifit~ ity of gastric lipases on milk TG in relation to fatty acid composition and TG structure. Regardless of milk fat con-