Genetic Variation among Major Human Geographic Groups Supports a Peculiar Evolutionary Trend in PAX9
A total of 172 persons from nine South Amerindian, three African and one Eskimo populations were studied in relation to the Paired box gene 9 (PAX9) exon 3 (138 base pairs) as well as its 59and 39flanking intronic segments (232 bp and 220 bp, respectively) and integrated with the information availab...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.648.705 2023-05-15T16:07:06+02:00 Genetic Variation among Major Human Geographic Groups Supports a Peculiar Evolutionary Trend in PAX9 Vanessa R. Paixão-côrtes Diogo Meyer Tiago V. Pereira Jacques Elion Rajagopal Krishnamoorthy Marco A. Zago Wilson A. Silva Francisco M. Salzano The Pennsylvania State University CiteSeerX Archives 2010 application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.648.705 http://halshs.archives-ouvertes.fr/docs/00/56/52/25/PDF/Paixao-Cortes_PO2011.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.648.705 http://halshs.archives-ouvertes.fr/docs/00/56/52/25/PDF/Paixao-Cortes_PO2011.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://halshs.archives-ouvertes.fr/docs/00/56/52/25/PDF/Paixao-Cortes_PO2011.pdf text 2010 ftciteseerx 2016-01-08T16:15:10Z A total of 172 persons from nine South Amerindian, three African and one Eskimo populations were studied in relation to the Paired box gene 9 (PAX9) exon 3 (138 base pairs) as well as its 59and 39flanking intronic segments (232 bp and 220 bp, respectively) and integrated with the information available for the same genetic region from individuals of different geographical origins. Nine mutations were scored in exon 3 and six in its flanking regions; four of them are new South American tribe-specific singletons. Exon3 nucleotide diversity is several orders of magnitude higher than its intronic regions. Additionally, a set of variants in the PAX9 and 101 other genes related with dentition can define at least some dental morphological differences between Sub-Saharan Africans and non-Africans, probably associated with adaptations after the Text eskimo* Unknown |
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ftciteseerx |
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English |
description |
A total of 172 persons from nine South Amerindian, three African and one Eskimo populations were studied in relation to the Paired box gene 9 (PAX9) exon 3 (138 base pairs) as well as its 59and 39flanking intronic segments (232 bp and 220 bp, respectively) and integrated with the information available for the same genetic region from individuals of different geographical origins. Nine mutations were scored in exon 3 and six in its flanking regions; four of them are new South American tribe-specific singletons. Exon3 nucleotide diversity is several orders of magnitude higher than its intronic regions. Additionally, a set of variants in the PAX9 and 101 other genes related with dentition can define at least some dental morphological differences between Sub-Saharan Africans and non-Africans, probably associated with adaptations after the |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Vanessa R. Paixão-côrtes Diogo Meyer Tiago V. Pereira Jacques Elion Rajagopal Krishnamoorthy Marco A. Zago Wilson A. Silva Francisco M. Salzano |
spellingShingle |
Vanessa R. Paixão-côrtes Diogo Meyer Tiago V. Pereira Jacques Elion Rajagopal Krishnamoorthy Marco A. Zago Wilson A. Silva Francisco M. Salzano Genetic Variation among Major Human Geographic Groups Supports a Peculiar Evolutionary Trend in PAX9 |
author_facet |
Vanessa R. Paixão-côrtes Diogo Meyer Tiago V. Pereira Jacques Elion Rajagopal Krishnamoorthy Marco A. Zago Wilson A. Silva Francisco M. Salzano |
author_sort |
Vanessa R. Paixão-côrtes |
title |
Genetic Variation among Major Human Geographic Groups Supports a Peculiar Evolutionary Trend in PAX9 |
title_short |
Genetic Variation among Major Human Geographic Groups Supports a Peculiar Evolutionary Trend in PAX9 |
title_full |
Genetic Variation among Major Human Geographic Groups Supports a Peculiar Evolutionary Trend in PAX9 |
title_fullStr |
Genetic Variation among Major Human Geographic Groups Supports a Peculiar Evolutionary Trend in PAX9 |
title_full_unstemmed |
Genetic Variation among Major Human Geographic Groups Supports a Peculiar Evolutionary Trend in PAX9 |
title_sort |
genetic variation among major human geographic groups supports a peculiar evolutionary trend in pax9 |
publishDate |
2010 |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.648.705 http://halshs.archives-ouvertes.fr/docs/00/56/52/25/PDF/Paixao-Cortes_PO2011.pdf |
genre |
eskimo* |
genre_facet |
eskimo* |
op_source |
http://halshs.archives-ouvertes.fr/docs/00/56/52/25/PDF/Paixao-Cortes_PO2011.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.648.705 http://halshs.archives-ouvertes.fr/docs/00/56/52/25/PDF/Paixao-Cortes_PO2011.pdf |
op_rights |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
_version_ |
1766403165102538752 |