Heat Shock Protein Response to Chronic Cold Exposure in Antarctic Expedition Members

• Main Authors: Ib Udaya, Shripad Patil
• Other Authors: The Pennsylvania State University CiteSeerX Archives
• Format: Text
• Language: English
• Subjects: Antarctic; Indian; The Antarctic; Antarc*; Antarctica
• Online Access: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.642.3967; http://www.ijsrp.org/research-paper-0514/ijsrp-p2906.pdf

Abstract- The heat shock response is seen when cells are exposed to extremes of thermal environment, which may be acute or chronic. The heat shock response is featured by increased expression of heat shock proteins (HSPs). One such key stresses is extreme cold environment as seen in Antarctica. The Antarctic continent on the planet Earth is full of environmental challenges. It is considered as natural stress model. The objective of this study was to study the effect of chronic cold environment on HSP levels. Seventeen healthy men of XXVI Indian Antarctic expedition with mean age of 39.7±1.95 years and age ranged from 29 to 56 years participated in this study. Antibodies of IgG, IgA and IgM classes against HSP65 were investigated by indirect ELISA method. Samples were collected in 2 phases. In phase-1, pre-expedition samples were collected before leaving to Antarctica at National Center for