Carotid plaque area: a tool for targeting and evaluating vascular preventive therapy. Stroke 2002; 33:2916–2922. 24 Greenland S. The need for reorientation toward cost-effective prediction: comments on evaluating the added predictive ability of a new mark
Background and Purpose—Carotid plaque area measured by ultrasound (cross-sectional area of longitudinal views of all plaques seen) was studied as a way of identifying patients at increased risk of stroke, myocardial infarction, and vascular death. Methods—Patients from an atherosclerosis prevention...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.604.6385 2023-05-15T16:29:54+02:00 Carotid plaque area: a tool for targeting and evaluating vascular preventive therapy. Stroke 2002; 33:2916–2922. 24 Greenland S. The need for reorientation toward cost-effective prediction: comments on evaluating the added predictive ability of a new mark J. David Spence Md Michael Eliasziw Phd Maria Dicicco Rvt Daniel G. Hackam Ramzy Galil Tara Lohmann The Pennsylvania State University CiteSeerX Archives application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.604.6385 http://www.kardiolab.ch/Spence_CarotidPlaqueArea.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.604.6385 http://www.kardiolab.ch/Spence_CarotidPlaqueArea.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://www.kardiolab.ch/Spence_CarotidPlaqueArea.pdf text ftciteseerx 2016-01-08T14:11:43Z Background and Purpose—Carotid plaque area measured by ultrasound (cross-sectional area of longitudinal views of all plaques seen) was studied as a way of identifying patients at increased risk of stroke, myocardial infarction, and vascular death. Methods—Patients from an atherosclerosis prevention clinic were followed up annually for up to 5 years (mean, 2.51.3 years) with baseline and follow-up measurements recorded. Plaque area progression (or regression) was defined as an increase (or decrease) of 0.05 cm2 from baseline. Results—Carotid plaque areas from 1686 patients were categorized into 4 quartile ranges: 0.00 to 0.11 cm2 (n422), 0.12 to 0.45 cm2 (n424), 0.46 to 1.18 cm2 (n421), and 1.19 to 6.73 cm2 (n419). The combined 5-year risk of stroke, myocardial infarction, and vascular death increased by quartile of plaque area: 5.6%, 10.7%, 13.9%, and 19.5%, respectively (P0.001) after adjustment for all baseline patient characteristics. A total of 1085 patients had 1 annual carotid plaque area measurements: 685 (63.1%) had carotid plaque progression, 306 (28.2%) had plaque regression, and 176 (16.2%) had no change in carotid plaque area over the period of follow-up. The 5-year adjusted risk of combined outcome was 9.4%, 7.6%, and 15.7 % for patients with carotid plaque area regression, no change, and progression, respectively (P0.003). Conclusions—Carotid plaque area and progression of plaque identified high-risk patients. Plaque measurement may be Text Greenland Unknown Greenland |
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Background and Purpose—Carotid plaque area measured by ultrasound (cross-sectional area of longitudinal views of all plaques seen) was studied as a way of identifying patients at increased risk of stroke, myocardial infarction, and vascular death. Methods—Patients from an atherosclerosis prevention clinic were followed up annually for up to 5 years (mean, 2.51.3 years) with baseline and follow-up measurements recorded. Plaque area progression (or regression) was defined as an increase (or decrease) of 0.05 cm2 from baseline. Results—Carotid plaque areas from 1686 patients were categorized into 4 quartile ranges: 0.00 to 0.11 cm2 (n422), 0.12 to 0.45 cm2 (n424), 0.46 to 1.18 cm2 (n421), and 1.19 to 6.73 cm2 (n419). The combined 5-year risk of stroke, myocardial infarction, and vascular death increased by quartile of plaque area: 5.6%, 10.7%, 13.9%, and 19.5%, respectively (P0.001) after adjustment for all baseline patient characteristics. A total of 1085 patients had 1 annual carotid plaque area measurements: 685 (63.1%) had carotid plaque progression, 306 (28.2%) had plaque regression, and 176 (16.2%) had no change in carotid plaque area over the period of follow-up. The 5-year adjusted risk of combined outcome was 9.4%, 7.6%, and 15.7 % for patients with carotid plaque area regression, no change, and progression, respectively (P0.003). Conclusions—Carotid plaque area and progression of plaque identified high-risk patients. Plaque measurement may be |
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The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
J. David Spence Md Michael Eliasziw Phd Maria Dicicco Rvt Daniel G. Hackam Ramzy Galil Tara Lohmann |
spellingShingle |
J. David Spence Md Michael Eliasziw Phd Maria Dicicco Rvt Daniel G. Hackam Ramzy Galil Tara Lohmann Carotid plaque area: a tool for targeting and evaluating vascular preventive therapy. Stroke 2002; 33:2916–2922. 24 Greenland S. The need for reorientation toward cost-effective prediction: comments on evaluating the added predictive ability of a new mark |
author_facet |
J. David Spence Md Michael Eliasziw Phd Maria Dicicco Rvt Daniel G. Hackam Ramzy Galil Tara Lohmann |
author_sort |
J. David Spence |
title |
Carotid plaque area: a tool for targeting and evaluating vascular preventive therapy. Stroke 2002; 33:2916–2922. 24 Greenland S. The need for reorientation toward cost-effective prediction: comments on evaluating the added predictive ability of a new mark |
title_short |
Carotid plaque area: a tool for targeting and evaluating vascular preventive therapy. Stroke 2002; 33:2916–2922. 24 Greenland S. The need for reorientation toward cost-effective prediction: comments on evaluating the added predictive ability of a new mark |
title_full |
Carotid plaque area: a tool for targeting and evaluating vascular preventive therapy. Stroke 2002; 33:2916–2922. 24 Greenland S. The need for reorientation toward cost-effective prediction: comments on evaluating the added predictive ability of a new mark |
title_fullStr |
Carotid plaque area: a tool for targeting and evaluating vascular preventive therapy. Stroke 2002; 33:2916–2922. 24 Greenland S. The need for reorientation toward cost-effective prediction: comments on evaluating the added predictive ability of a new mark |
title_full_unstemmed |
Carotid plaque area: a tool for targeting and evaluating vascular preventive therapy. Stroke 2002; 33:2916–2922. 24 Greenland S. The need for reorientation toward cost-effective prediction: comments on evaluating the added predictive ability of a new mark |
title_sort |
carotid plaque area: a tool for targeting and evaluating vascular preventive therapy. stroke 2002; 33:2916–2922. 24 greenland s. the need for reorientation toward cost-effective prediction: comments on evaluating the added predictive ability of a new mark |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.604.6385 http://www.kardiolab.ch/Spence_CarotidPlaqueArea.pdf |
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Greenland |
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Greenland |
genre |
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genre_facet |
Greenland |
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http://www.kardiolab.ch/Spence_CarotidPlaqueArea.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.604.6385 http://www.kardiolab.ch/Spence_CarotidPlaqueArea.pdf |
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Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
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