Cholinergic and adrenergic tones in the control of the heart rate in teleosts. How should they be calculated? Comp Biochem Physiol 118A
ABSTRACT. Cholinergic and adrenergic tones were calculated for three different teleost fish species: Gadus morhua, Labrus bergylta, and Sparus aurata using atropine as a muscarinic receptor antagonist and either sotalol or propranolol as β-adrenoceptor antagonists. Depending on the order of administ...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.603.3473 2023-05-15T16:19:13+02:00 Cholinergic and adrenergic tones in the control of the heart rate in teleosts. How should they be calculated? Comp Biochem Physiol 118A Jordi Altimiras Abbas Aissaoui Lluis Tort Michael Axelsson The Pennsylvania State University CiteSeerX Archives 1997 application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.603.3473 en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.603.3473 Metadata may be used without restrictions as long as the oai identifier remains attached to it. https://people.ifm.liu.se/jordi/PDFS/ARJ04 CBP 97.pdf olol text 1997 ftciteseerx 2016-01-08T14:08:19Z ABSTRACT. Cholinergic and adrenergic tones were calculated for three different teleost fish species: Gadus morhua, Labrus bergylta, and Sparus aurata using atropine as a muscarinic receptor antagonist and either sotalol or propranolol as β-adrenoceptor antagonists. Depending on the order of administration of atropine and the two β-adrenoceptor antagonists, it was observed that propranolol but not sotalol enhanced cholinergic tone. Thus, if propranolol is used to determine autonomic cardiac influences, it has to be injected after atropine and not before. Differences in intrinsic heart rate were observed between treatments in two of the three species studied, suggesting the activity of a non-cholinergic non-adrenergic mechanism in heart rate control in fish. Different models to calculate cholinergic and adrenergic tones are discussed. The additive model described by other authors is appropriate provided that no interaction exists between cholinergic and adrenergic influences. We demonstrate no interaction in the species studied in this experiment. Finally, a modification of the additive model that uses R-R interval instead of heart rate in the computation is proposed. This is justified with a computer simulation in terms of the linearity of the response given the reciprocal relationship between R-R interval and Text Gadus morhua Unknown |
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olol Jordi Altimiras Abbas Aissaoui Lluis Tort Michael Axelsson Cholinergic and adrenergic tones in the control of the heart rate in teleosts. How should they be calculated? Comp Biochem Physiol 118A |
topic_facet |
olol |
description |
ABSTRACT. Cholinergic and adrenergic tones were calculated for three different teleost fish species: Gadus morhua, Labrus bergylta, and Sparus aurata using atropine as a muscarinic receptor antagonist and either sotalol or propranolol as β-adrenoceptor antagonists. Depending on the order of administration of atropine and the two β-adrenoceptor antagonists, it was observed that propranolol but not sotalol enhanced cholinergic tone. Thus, if propranolol is used to determine autonomic cardiac influences, it has to be injected after atropine and not before. Differences in intrinsic heart rate were observed between treatments in two of the three species studied, suggesting the activity of a non-cholinergic non-adrenergic mechanism in heart rate control in fish. Different models to calculate cholinergic and adrenergic tones are discussed. The additive model described by other authors is appropriate provided that no interaction exists between cholinergic and adrenergic influences. We demonstrate no interaction in the species studied in this experiment. Finally, a modification of the additive model that uses R-R interval instead of heart rate in the computation is proposed. This is justified with a computer simulation in terms of the linearity of the response given the reciprocal relationship between R-R interval and |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Jordi Altimiras Abbas Aissaoui Lluis Tort Michael Axelsson |
author_facet |
Jordi Altimiras Abbas Aissaoui Lluis Tort Michael Axelsson |
author_sort |
Jordi Altimiras |
title |
Cholinergic and adrenergic tones in the control of the heart rate in teleosts. How should they be calculated? Comp Biochem Physiol 118A |
title_short |
Cholinergic and adrenergic tones in the control of the heart rate in teleosts. How should they be calculated? Comp Biochem Physiol 118A |
title_full |
Cholinergic and adrenergic tones in the control of the heart rate in teleosts. How should they be calculated? Comp Biochem Physiol 118A |
title_fullStr |
Cholinergic and adrenergic tones in the control of the heart rate in teleosts. How should they be calculated? Comp Biochem Physiol 118A |
title_full_unstemmed |
Cholinergic and adrenergic tones in the control of the heart rate in teleosts. How should they be calculated? Comp Biochem Physiol 118A |
title_sort |
cholinergic and adrenergic tones in the control of the heart rate in teleosts. how should they be calculated? comp biochem physiol 118a |
publishDate |
1997 |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.603.3473 |
genre |
Gadus morhua |
genre_facet |
Gadus morhua |
op_source |
https://people.ifm.liu.se/jordi/PDFS/ARJ04 CBP 97.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.603.3473 |
op_rights |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
_version_ |
1766005564812296192 |