Expression of a duplicate Na,K-ATPase b1 isoform in the European eel (Anguilla anguilla
Integrative Comp Physiol 279: R222–R229, 2000.—Recent studies on teleost fish have suggested that their genomes have undergone ancient polyploidization events resulting in the duplication of the genome. A duplicate copy of the Na,K-ATPase b1-isoform (called b233) has been identified in the European...
Main Authors: | , , , , , , , |
---|---|
Other Authors: | |
Format: | Text |
Language: | English |
Published: |
2000
|
Subjects: | |
Online Access: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.597.8407 http://www.bio.georgiasouthern.edu/Bio-home/Cutler/EelNa,K-ATPaseb233.pdf |
Summary: | Integrative Comp Physiol 279: R222–R229, 2000.—Recent studies on teleost fish have suggested that their genomes have undergone ancient polyploidization events resulting in the duplication of the genome. A duplicate copy of the Na,K-ATPase b1-isoform (called b233) has been identified in the European eel (Anguilla anguilla). The b233-isoform shares high levels of nucleotide (74.8%) and amino acid (69.9%) homology with the eel b1-subunit as well as other vertebrate b1-sequences. Compared with the widely expressed b1-iso-form, expression of b233-mRNA is mainly restricted to epi-thelial tissues. Seawater acclimation induced increases in b233-mRNA levels in kidney, gill, and intestine of migratory “silver ” but not the nonmigratory “yellow ” adult eels, sug-gesting that the factors responsible for this upregulation are themselves developmentally regulated. Expression of a vari- |
---|