The Dual Origin and Siberian Affinities of Native American
The Y chromosomes of 549 individuals from Siberia and the Americas were analyzed for 12 biallelic markers, which defined 15 haplogroups. The addition of four microsatellite markers increased the number of haplotypes to 111. The major Native American founding lineage, haplogroup M3, accounted for 66...
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ftciteseerx:oai:CiteSeerX.psu:10.1.1.589.4811 2023-05-15T15:54:52+02:00 The Dual Origin and Siberian Affinities of Native American Y Chromosomes Theodore G. Schurr Peter A. Underhill Douglas C. Wallace The Pennsylvania State University CiteSeerX Archives application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.589.4811 http://www.bionet.nsc.ru/labs/mtgenome/Publications/Lell_2002_DualOrigin.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.589.4811 http://www.bionet.nsc.ru/labs/mtgenome/Publications/Lell_2002_DualOrigin.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://www.bionet.nsc.ru/labs/mtgenome/Publications/Lell_2002_DualOrigin.pdf text ftciteseerx 2016-01-08T13:24:41Z The Y chromosomes of 549 individuals from Siberia and the Americas were analyzed for 12 biallelic markers, which defined 15 haplogroups. The addition of four microsatellite markers increased the number of haplotypes to 111. The major Native American founding lineage, haplogroup M3, accounted for 66 % of male Y chromosomes and was defined by the biallelic markers M89, M9, M45, and M3. The founder haplotype also harbored the microsatellite alleles DYS19 (10 repeats), DYS388 (11 repeats), DYS390 (11 repeats), and DYS391 (10 repeats). In Siberia, the M3 haplogroup was confined to the Chukotka peninsula, adjacent to Alaska. The second major group of Native American Y chromosomes, haplogroup M45, accounted for about one-quarter of male lineages. M45 was subdivided by the biallelic marker M173 and by the four microsatellite loci alleles into two major subdivisions: M45a, which is found throughout the Americas, and M45b, which incorporates the M173 variant and is concentrated in North and Central America. In Siberia, M45a haplotypes, including the direct ancestor of haplogroup M3, are concentrated in Middle Siberia, whereas M45b haplotypes are found in the Lower Amur River and Sea of Okhotsk regions of eastern Siberia. Among the remaining 5 % of Native American Y chromosomes is haplogroup RPS4Y-T, found in North America. In Siberia, this haplogroup, along with haplogroup M45b, is concentrated in the Lower Amur River/Sea of Okhotsk region. These data suggest that Native American male lineages were derived from two major Siberian migrations. The first migration originated in southern Middle Siberia Text Chukotka Chukotka Peninsula Alaska Siberia Unknown Okhotsk The ''Y'' ENVELOPE(-112.453,-112.453,57.591,57.591) |
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English |
description |
The Y chromosomes of 549 individuals from Siberia and the Americas were analyzed for 12 biallelic markers, which defined 15 haplogroups. The addition of four microsatellite markers increased the number of haplotypes to 111. The major Native American founding lineage, haplogroup M3, accounted for 66 % of male Y chromosomes and was defined by the biallelic markers M89, M9, M45, and M3. The founder haplotype also harbored the microsatellite alleles DYS19 (10 repeats), DYS388 (11 repeats), DYS390 (11 repeats), and DYS391 (10 repeats). In Siberia, the M3 haplogroup was confined to the Chukotka peninsula, adjacent to Alaska. The second major group of Native American Y chromosomes, haplogroup M45, accounted for about one-quarter of male lineages. M45 was subdivided by the biallelic marker M173 and by the four microsatellite loci alleles into two major subdivisions: M45a, which is found throughout the Americas, and M45b, which incorporates the M173 variant and is concentrated in North and Central America. In Siberia, M45a haplotypes, including the direct ancestor of haplogroup M3, are concentrated in Middle Siberia, whereas M45b haplotypes are found in the Lower Amur River and Sea of Okhotsk regions of eastern Siberia. Among the remaining 5 % of Native American Y chromosomes is haplogroup RPS4Y-T, found in North America. In Siberia, this haplogroup, along with haplogroup M45b, is concentrated in the Lower Amur River/Sea of Okhotsk region. These data suggest that Native American male lineages were derived from two major Siberian migrations. The first migration originated in southern Middle Siberia |
author2 |
The Pennsylvania State University CiteSeerX Archives |
format |
Text |
author |
Y Chromosomes Theodore G. Schurr Peter A. Underhill Douglas C. Wallace |
spellingShingle |
Y Chromosomes Theodore G. Schurr Peter A. Underhill Douglas C. Wallace The Dual Origin and Siberian Affinities of Native American |
author_facet |
Y Chromosomes Theodore G. Schurr Peter A. Underhill Douglas C. Wallace |
author_sort |
Y Chromosomes |
title |
The Dual Origin and Siberian Affinities of Native American |
title_short |
The Dual Origin and Siberian Affinities of Native American |
title_full |
The Dual Origin and Siberian Affinities of Native American |
title_fullStr |
The Dual Origin and Siberian Affinities of Native American |
title_full_unstemmed |
The Dual Origin and Siberian Affinities of Native American |
title_sort |
dual origin and siberian affinities of native american |
url |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.589.4811 http://www.bionet.nsc.ru/labs/mtgenome/Publications/Lell_2002_DualOrigin.pdf |
long_lat |
ENVELOPE(-112.453,-112.453,57.591,57.591) |
geographic |
Okhotsk The ''Y'' |
geographic_facet |
Okhotsk The ''Y'' |
genre |
Chukotka Chukotka Peninsula Alaska Siberia |
genre_facet |
Chukotka Chukotka Peninsula Alaska Siberia |
op_source |
http://www.bionet.nsc.ru/labs/mtgenome/Publications/Lell_2002_DualOrigin.pdf |
op_relation |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.589.4811 http://www.bionet.nsc.ru/labs/mtgenome/Publications/Lell_2002_DualOrigin.pdf |
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Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
_version_ |
1766390110306172928 |